Pharmacokinetics and Safety of Intravenous Voriconazole in Children after Single- or Multiple-Dose Administration

Thomas J. Walsh; Mats O. Karlsson; Timothy Driscoll; Adriano G. Arguedas; Peter Adamson; Xavier Saez-Llorens; Ajay J. Vora; Antonio C. Arrieta; Jeffrey Blumer; Irja Lutsar; Peter Milligan; Nolan Wood

doi:10.1128/AAC.48.6.2166-2172.2004

DOI: 10.1128/AAC.48.6.2166-2172.2004

Article Information

DOI

https://doi.org/10.1128/AAC.48.6.2166-2172.2004

PubMed

15155217

Published By

American Society for Microbiology Journals

History

Received November 3, 2003
Returned for modification December 12, 2003
Accepted February 4, 2004
Published online May 21, 2004.

Author Information

Thomas J. Walsh¹ *,
Mats O. Karlsson²,
Timothy Driscoll³,
Adriano G. Arguedas⁴,
Peter Adamson⁵,⁶,
Xavier Saez-Llorens⁷,
Ajay J. Vora⁸,
Antonio C. Arrieta⁹,
Jeffrey Blumer⁶,¹⁰,
Irja Lutsar¹¹,
Peter Milligan¹¹ and
Nolan Wood¹¹

¹National Cancer Institute and
⁶Pediatric Pharmacology Unit, National Institute of Child Health and Human Development
²Bethesda, Maryland; Uppsala University, Uppsala, Sweden
³Duke University Medical Center, Durham, North Carolina
⁴Instituto Costarricense de Invetigaciones Clinicas and National Children's Hospital, San Jose, Costa Rica
⁵Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
⁷Hospital del Niños, Ciudad de Panama, Panama
⁸Sheffield Children's Hospital, Sheffield
¹¹Pfizer Global Research and Development, Sandwich, Kent, United Kingdom
⁹Children's Hospital of Orange County, Orange, California
¹⁰University Hospitals of Cleveland, Cleveland, Ohio

↵* Corresponding author. Mailing address: Pediatric Oncology Branch, National Cancer Institute, Bldg. 10, Rm. 13N240, Bethesda, MD 20892. Phone: (301) 496-7103. Fax: (301) 402-0575. E-mail: walsht{at}mail.nih.gov .

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