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Mechanisms of Resistance

Screening and Characterization of Mutations in Isoniazid-Resistant Mycobacterium tuberculosis Isolates Obtained in Brazil

Rosilene Fressatti Cardoso, Robert C. Cooksey, Glenn P. Morlock, Patricia Barco, Leticia Cecon, Francisco Forestiero, Clarice Q. F. Leite, Daisy N. Sato, Maria de Lourdes Shikama, Elsa M. Mamizuka, Rosario D. C. Hirata, Mario H. Hirata
Rosilene Fressatti Cardoso
1Department of Clinical Analysis, State University of Maringá, Paraná
2University of São Paulo, São Paulo, Brazil
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Robert C. Cooksey
3Division of AIDS, STD, and TB Laboratory Research, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
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Glenn P. Morlock
3Division of AIDS, STD, and TB Laboratory Research, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
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  • For correspondence: gmorlock@cdc.gov
Patricia Barco
2University of São Paulo, São Paulo, Brazil
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Leticia Cecon
2University of São Paulo, São Paulo, Brazil
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Francisco Forestiero
2University of São Paulo, São Paulo, Brazil
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Clarice Q. F. Leite
4Department of Biologic Sciences, Paulista State University, Paulista
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Daisy N. Sato
5Institute Adolfo Lutz, Ribeirão Preto
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Maria de Lourdes Shikama
6Institute Adolfo Lutz, Sorocaba
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Elsa M. Mamizuka
2University of São Paulo, São Paulo, Brazil
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Rosario D. C. Hirata
2University of São Paulo, São Paulo, Brazil
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Mario H. Hirata
2University of São Paulo, São Paulo, Brazil
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DOI: 10.1128/AAC.48.9.3373-3381.2004
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Article Information

DOI 
https://doi.org/10.1128/AAC.48.9.3373-3381.2004
PubMed 
15328099

Published By 
American Society for Microbiology Journals
History 
  • Received April 12, 2004
  • Returned for modification May 20, 2004
  • Accepted May 24, 2004
  • Published online August 24, 2004.

Copyright & Usage 
Copyright © 2004 American Society for Microbiology

Author Information

  1. Rosilene Fressatti Cardoso1,2,
  2. Robert C. Cooksey3,
  3. Glenn P. Morlock3*,
  4. Patricia Barco2,
  5. Leticia Cecon2,
  6. Francisco Forestiero2,
  7. Clarice Q. F. Leite4,
  8. Daisy N. Sato5,
  9. Maria de Lourdes Shikama6,
  10. Elsa M. Mamizuka2,
  11. Rosario D. C. Hirata2 and
  12. Mario H. Hirata2
  1. 1Department of Clinical Analysis, State University of Maringá, Paraná
  2. 4Department of Biologic Sciences, Paulista State University, Paulista
  3. 5Institute Adolfo Lutz, Ribeirão Preto
  4. 6Institute Adolfo Lutz, Sorocaba
  5. 2University of São Paulo, São Paulo, Brazil
  6. 3Division of AIDS, STD, and TB Laboratory Research, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
  • ↵* Corresponding author. Mailing address: Centers for Disease Control and Prevention, 1600 Clifton Rd., Mailstop F08, Atlanta, GA 30333. Phone: (404) 639-0147. Fax: (404) 639-1287. E-mail: gmorlock{at}cdc.gov .

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Screening and Characterization of Mutations in Isoniazid-Resistant Mycobacterium tuberculosis Isolates Obtained in Brazil
Rosilene Fressatti Cardoso, Robert C. Cooksey, Glenn P. Morlock, Patricia Barco, Leticia Cecon, Francisco Forestiero, Clarice Q. F. Leite, Daisy N. Sato, Maria de Lourdes Shikama, Elsa M. Mamizuka, Rosario D. C. Hirata, Mario H. Hirata
Antimicrobial Agents and Chemotherapy Aug 2004, 48 (9) 3373-3381; DOI: 10.1128/AAC.48.9.3373-3381.2004

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Screening and Characterization of Mutations in Isoniazid-Resistant Mycobacterium tuberculosis Isolates Obtained in Brazil
Rosilene Fressatti Cardoso, Robert C. Cooksey, Glenn P. Morlock, Patricia Barco, Leticia Cecon, Francisco Forestiero, Clarice Q. F. Leite, Daisy N. Sato, Maria de Lourdes Shikama, Elsa M. Mamizuka, Rosario D. C. Hirata, Mario H. Hirata
Antimicrobial Agents and Chemotherapy Aug 2004, 48 (9) 3373-3381; DOI: 10.1128/AAC.48.9.3373-3381.2004
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KEYWORDS

antitubercular agents
isoniazid
mutation
Mycobacterium tuberculosis
tuberculosis

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