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Clinical Therapeutics

Efficacy of the Combination Rifampin-Streptomycin in Preventing Growth of Mycobacterium ulcerans in Early Lesions of Buruli Ulcer in Humans

S. Etuaful, B. Carbonnelle, J. Grosset, S. Lucas, C. Horsfield, R. Phillips, M. Evans, D. Ofori-Adjei, E. Klustse, J. Owusu-Boateng, G. K. Amedofu, P. Awuah, E. Ampadu, G. Amofah, K. Asiedu, M. Wansbrough-Jones
S. Etuaful
St. Martin's Catholic Hospital, Agroyesum, Ghana
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B. Carbonnelle
Laboratoire de Bactériologie, CHU (University Hospital) Angers, Angers, France
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J. Grosset
Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, Maryland
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S. Lucas
St. Thomas's Hospital Campus, UMDS, London, United Kingdom
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C. Horsfield
St. Thomas's Hospital Campus, UMDS, London, United Kingdom
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R. Phillips
St. George's Hospital Medical School, London, United Kingdom
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M. Evans
St. George's Hospital Medical School, London, United Kingdom
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D. Ofori-Adjei
Noguchi Memorial Institute for Medical Research, Accra, Ghana
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E. Klustse
Dunkwa Government Hospital, Dunkwa-on-Offin, Ghana
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J. Owusu-Boateng
Public Health Reference Laboratory, Kumasi, Ghana
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G. K. Amedofu
Department of Ear, Nose and Throat, Hearing Assessment Center, Komfo Anokye Teaching Hospital, Kumasi, Ghana
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P. Awuah
Department of Ear, Nose and Throat, Hearing Assessment Center, Komfo Anokye Teaching Hospital, Kumasi, Ghana
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E. Ampadu
Ghana Health Service, Public Health Division, Accra, Ghana
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G. Amofah
Ghana Health Service, Public Health Division, Accra, Ghana
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K. Asiedu
World Health Organization, Geneva, Switzerland
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M. Wansbrough-Jones
St. George's Hospital Medical School, London, United Kingdom
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  • For correspondence: wansbrou@sghms.ac.uk
DOI: 10.1128/AAC.49.8.3182-3186.2005
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Article Information

DOI 
https://doi.org/10.1128/AAC.49.8.3182-3186.2005
PubMed 
16048922

Published By 
American Society for Microbiology Journals
History 
  • Received March 4, 2005
  • Returned for modification April 11, 2005
  • Accepted April 29, 2005
  • Published online July 26, 2005.

Copyright & Usage 
American Society for Microbiology

Author Information

  1. S. Etuaful1,
  2. B. Carbonnelle2,
  3. J. Grosset3,
  4. S. Lucas4,
  5. C. Horsfield4,
  6. R. Phillips5,
  7. M. Evans5,
  8. D. Ofori-Adjei6,
  9. E. Klustse7,
  10. J. Owusu-Boateng8,
  11. G. K. Amedofu9,
  12. P. Awuah9,
  13. E. Ampadu10,
  14. G. Amofah10,
  15. K. Asiedu11 and
  16. M. Wansbrough-Jones5*
  1. 1St. Martin's Catholic Hospital, Agroyesum, Ghana
  2. 2Laboratoire de Bactériologie, CHU (University Hospital) Angers, Angers, France
  3. 3Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, Maryland
  4. 4St. Thomas's Hospital Campus, UMDS, London, United Kingdom
  5. 5St. George's Hospital Medical School, London, United Kingdom
  6. 6Noguchi Memorial Institute for Medical Research, Accra, Ghana
  7. 7Dunkwa Government Hospital, Dunkwa-on-Offin, Ghana
  8. 8Public Health Reference Laboratory, Kumasi, Ghana
  9. 9Department of Ear, Nose and Throat, Hearing Assessment Center, Komfo Anokye Teaching Hospital, Kumasi, Ghana
  10. 10Ghana Health Service, Public Health Division, Accra, Ghana
  11. 11World Health Organization, Geneva, Switzerland
  • ↵*Corresponding author. Mailing address: St. George's Hospital Medical School, Department of Cellular and Molecular Medicine, Cranmer Terrace, London SW17 0RE, United Kingdom. Phone: 44 2087255827. Fax: 44 2087253487. E-mail: wansbrou{at}sghms.ac.uk.
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Efficacy of the Combination Rifampin-Streptomycin in Preventing Growth of Mycobacterium ulcerans in Early Lesions of Buruli Ulcer in Humans
S. Etuaful, B. Carbonnelle, J. Grosset, S. Lucas, C. Horsfield, R. Phillips, M. Evans, D. Ofori-Adjei, E. Klustse, J. Owusu-Boateng, G. K. Amedofu, P. Awuah, E. Ampadu, G. Amofah, K. Asiedu, M. Wansbrough-Jones
Antimicrobial Agents and Chemotherapy Jul 2005, 49 (8) 3182-3186; DOI: 10.1128/AAC.49.8.3182-3186.2005

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Efficacy of the Combination Rifampin-Streptomycin in Preventing Growth of Mycobacterium ulcerans in Early Lesions of Buruli Ulcer in Humans
S. Etuaful, B. Carbonnelle, J. Grosset, S. Lucas, C. Horsfield, R. Phillips, M. Evans, D. Ofori-Adjei, E. Klustse, J. Owusu-Boateng, G. K. Amedofu, P. Awuah, E. Ampadu, G. Amofah, K. Asiedu, M. Wansbrough-Jones
Antimicrobial Agents and Chemotherapy Jul 2005, 49 (8) 3182-3186; DOI: 10.1128/AAC.49.8.3182-3186.2005
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