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Pharmacology

Oxazolidinones Inhibit Cellular Proliferation via Inhibition of Mitochondrial Protein Synthesis

Eva E. Nagiec, Luping Wu, Steve M. Swaney, John G. Chosay, Daniel E. Ross, Joan K. Brieland, Karen L. Leach
Eva E. Nagiec
2Department of Cardiovascular Cellular and Molecular Pharmacology, Pfizer, St. Louis, Missouri
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Luping Wu
1Department of Antibacterial Pharmacology, Pfizer, Ann Arbor, Michigan
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Steve M. Swaney
1Department of Antibacterial Pharmacology, Pfizer, Ann Arbor, Michigan
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John G. Chosay
1Department of Antibacterial Pharmacology, Pfizer, Ann Arbor, Michigan
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Daniel E. Ross
1Department of Antibacterial Pharmacology, Pfizer, Ann Arbor, Michigan
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Joan K. Brieland
1Department of Antibacterial Pharmacology, Pfizer, Ann Arbor, Michigan
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Karen L. Leach
1Department of Antibacterial Pharmacology, Pfizer, Ann Arbor, Michigan
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  • For correspondence: karen.l.leach@pfizer.com
DOI: 10.1128/AAC.49.9.3896-3902.2005
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Article Information

DOI 
https://doi.org/10.1128/AAC.49.9.3896-3902.2005
PubMed 
16127068

Published By 
American Society for Microbiology Journals
History 
  • Received March 1, 2005
  • Returned for modification April 3, 2005
  • Accepted May 27, 2005
  • Published online August 26, 2005.

Copyright & Usage 
Copyright © 2005 American Society for Microbiology

Author Information

  1. Eva E. Nagiec2,
  2. Luping Wu1,
  3. Steve M. Swaney1,
  4. John G. Chosay1,
  5. Daniel E. Ross1,
  6. Joan K. Brieland1 and
  7. Karen L. Leach1*
  1. 1Department of Antibacterial Pharmacology, Pfizer, Ann Arbor, Michigan
  2. 2Department of Cardiovascular Cellular and Molecular Pharmacology, Pfizer, St. Louis, Missouri
  • ↵* Corresponding author. Mailing address: 2800 Plymouth Rd., Ann Arbor, MI 48105. Phone: (734) 622-7343. Fax: (734) 622-7158. E-mail: karen.l.leach{at}pfizer.com .

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Oxazolidinones Inhibit Cellular Proliferation via Inhibition of Mitochondrial Protein Synthesis
Eva E. Nagiec, Luping Wu, Steve M. Swaney, John G. Chosay, Daniel E. Ross, Joan K. Brieland, Karen L. Leach
Antimicrobial Agents and Chemotherapy Aug 2005, 49 (9) 3896-3902; DOI: 10.1128/AAC.49.9.3896-3902.2005

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Oxazolidinones Inhibit Cellular Proliferation via Inhibition of Mitochondrial Protein Synthesis
Eva E. Nagiec, Luping Wu, Steve M. Swaney, John G. Chosay, Daniel E. Ross, Joan K. Brieland, Karen L. Leach
Antimicrobial Agents and Chemotherapy Aug 2005, 49 (9) 3896-3902; DOI: 10.1128/AAC.49.9.3896-3902.2005
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KEYWORDS

cell proliferation
Mitochondria, Heart
Oxazoles
Protein Synthesis Inhibitors

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