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Mechanisms of Resistance

Heterogeneous Macrolide Resistance and Gene Conversion in the Pneumococcus

Nicole Wolter, Anthony M. Smith, David J. Farrell, Keith P. Klugman
Nicole Wolter
1Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases, Medical Research Council and University of the Witwatersrand, Johannesburg, South Africa
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  • For correspondence: nicolew@nicd.ac.za
Anthony M. Smith
1Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases, Medical Research Council and University of the Witwatersrand, Johannesburg, South Africa
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David J. Farrell
2GR Micro Ltd., London, United Kingdom
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Keith P. Klugman
1Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases, Medical Research Council and University of the Witwatersrand, Johannesburg, South Africa
3Department of Global Health, Rollins School of Public Health, and Division of Infectious Diseases, School of Medicine, Emory University, Atlanta, Georgia
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DOI: 10.1128/AAC.50.1.359-361.2006
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Article Information

DOI 
https://doi.org/10.1128/AAC.50.1.359-361.2006
PubMed 
16377711

Published By 
American Society for Microbiology Journals
History 
  • Received August 15, 2005
  • Returned for modification September 21, 2005
  • Accepted September 28, 2005
  • Published online December 23, 2005.

Copyright & Usage 
Copyright © 2006 American Society for Microbiology

Author Information

  1. Nicole Wolter1*,
  2. Anthony M. Smith1,
  3. David J. Farrell2 and
  4. Keith P. Klugman1,3
  1. 1Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases, Medical Research Council and University of the Witwatersrand, Johannesburg, South Africa
  2. 2GR Micro Ltd., London, United Kingdom
  3. 3Department of Global Health, Rollins School of Public Health, and Division of Infectious Diseases, School of Medicine, Emory University, Atlanta, Georgia
  • ↵* Corresponding author. Mailing address: Respiratory and Meningeal Pathogens Research Unit, National Institute for Communicable Diseases, Private Bag X4, Sandringham, 2131, South Africa. Phone: 27-11-555-0352. Fax: 27-11-555-0437. E-mail: nicolew{at}nicd.ac.za .
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Heterogeneous Macrolide Resistance and Gene Conversion in the Pneumococcus
Nicole Wolter, Anthony M. Smith, David J. Farrell, Keith P. Klugman
Antimicrobial Agents and Chemotherapy Dec 2005, 50 (1) 359-361; DOI: 10.1128/AAC.50.1.359-361.2006

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Heterogeneous Macrolide Resistance and Gene Conversion in the Pneumococcus
Nicole Wolter, Anthony M. Smith, David J. Farrell, Keith P. Klugman
Antimicrobial Agents and Chemotherapy Dec 2005, 50 (1) 359-361; DOI: 10.1128/AAC.50.1.359-361.2006
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KEYWORDS

Anti-Bacterial Agents
Drug Resistance, Bacterial
Gene Conversion
macrolides
RNA, Ribosomal, 23S
Streptococcus pneumoniae

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