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Pharmacology

Impaired Target Site Penetration of Vancomycin in Diabetic Patients following Cardiac Surgery

Keso Skhirtladze, Doris Hutschala, Tatjana Fleck, Florian Thalhammer, Marek Ehrlich, Thomas Vukovich, Markus Müller, Edda M. Tschernko
Keso Skhirtladze
1Department of Cardiothoracic and Vascular Anesthesia & CCM
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Doris Hutschala
1Department of Cardiothoracic and Vascular Anesthesia & CCM
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Tatjana Fleck
2Department of Cardiothoracic Surgery
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Florian Thalhammer
3Department of Infectious Diseases
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Marek Ehrlich
2Department of Cardiothoracic Surgery
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Thomas Vukovich
4Department of Laboratory Medicine
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Markus Müller
5Department of Clinical Pharmacology, University of Vienna, General Hospital, Vienna, Austria
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Edda M. Tschernko
1Department of Cardiothoracic and Vascular Anesthesia & CCM
5Department of Clinical Pharmacology, University of Vienna, General Hospital, Vienna, Austria
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  • For correspondence: edda.tschernko@meduniwien.ac.at
DOI: 10.1128/AAC.50.4.1372-1375.2006
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Article Information

DOI 
https://doi.org/10.1128/AAC.50.4.1372-1375.2006
PubMed 
16569854

Published By 
American Society for Microbiology Journals
History 
  • Received June 28, 2005
  • Returned for modification September 30, 2005
  • Accepted January 13, 2006
  • Published online March 28, 2006.

Copyright & Usage 
Copyright © 2006 American Society for Microbiology

Author Information

  1. Keso Skhirtladze1,
  2. Doris Hutschala1,
  3. Tatjana Fleck2,
  4. Florian Thalhammer3,
  5. Marek Ehrlich2,
  6. Thomas Vukovich4,
  7. Markus Müller5 and
  8. Edda M. Tschernko1,5*
  1. 1Department of Cardiothoracic and Vascular Anesthesia & CCM
  2. 2Department of Cardiothoracic Surgery
  3. 3Department of Infectious Diseases
  4. 4Department of Laboratory Medicine
  5. 5Department of Clinical Pharmacology, University of Vienna, General Hospital, Vienna, Austria
  • ↵* Corresponding author. Mailing address: Department of Cardiothoracic and Vascular Anesthesia & CCM, University of Vienna, General Hospital, Waeringer Guertel 18-20, A-1090 Vienna, Austria. Phone: 43-1-40400-4109. Fax: 43-1-40400-4110. E-mail: edda.tschernko{at}meduniwien.ac.at .
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Impaired Target Site Penetration of Vancomycin in Diabetic Patients following Cardiac Surgery
Keso Skhirtladze, Doris Hutschala, Tatjana Fleck, Florian Thalhammer, Marek Ehrlich, Thomas Vukovich, Markus Müller, Edda M. Tschernko
Antimicrobial Agents and Chemotherapy Mar 2006, 50 (4) 1372-1375; DOI: 10.1128/AAC.50.4.1372-1375.2006

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Impaired Target Site Penetration of Vancomycin in Diabetic Patients following Cardiac Surgery
Keso Skhirtladze, Doris Hutschala, Tatjana Fleck, Florian Thalhammer, Marek Ehrlich, Thomas Vukovich, Markus Müller, Edda M. Tschernko
Antimicrobial Agents and Chemotherapy Mar 2006, 50 (4) 1372-1375; DOI: 10.1128/AAC.50.4.1372-1375.2006
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KEYWORDS

diabetes mellitus
Postoperative Complications
Soft Tissue Infections
staphylococcal infections
vancomycin

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