Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia

Aki Okazaki; Matthew B. Avison

doi:10.1128/AAC.00795-06

Log in
My alerts
My Cart

Main menu

Home
Articles
For Authors
About the Journal
Subscribe
- Members
- Institutions

User menu

Log in
My alerts
My Cart

Search

Search for this keyword

Advanced search

Search for this keyword

Advanced Search

Home
Articles
For Authors
About the Journal
Subscribe
- Members
- Institutions

Mechanisms of Resistance

Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia

Aki Okazaki, Matthew B. Avison

Aki Okazaki

Bristol Centre for Antimicrobial Research and Evaluation, Department of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Matthew B. Avison

Bristol Centre for Antimicrobial Research and Evaluation, Department of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: matthewb.Avison@bris.ac.uk

DOI: 10.1128/AAC.00795-06

Article
Figures & Data
Info & Metrics
PDF

Article Figures & Data

Tables

TABLE 1.

MICs of various aminoglycosides against recombinant E. coli DH5α producing or not producing S. maltophilia APH(3′)-IIc and against S. maltophilia K279a and an aph^FS derivative

Strain or recombinant and condition	MIC (mg/liter) of^a:
Strain or recombinant and condition	AMI	BUT	GENT	KAN	LIV	NEO	PARO	SIS	TOB
DH5α::pBAD
No arabinose	0.5	0.125	1	0.25	4	0.5	0.25	0.125	0.5
With arabinose	0.5	0.125	1	0.25	4	0.5	0.25	0.125	0.5
DH5α::pBAD[aph(3′)-II]
No arabinose	0.5	0.125	1	0.25	4	0.5	0.25	0.125	0.5
With arabinose	4	4	1	>256	8	64	128	0.125	8
K279a	64	8	16	256	128	512	256	8	32
K279a (aph^FS)	64	1	16	8	128	64	64	8	32

↵ a MICs were determined using agar dilution on Muller-Hinton agar. Abbreviations: AMI, amikacin; BUT, butirosin; GENT, gentamicin; KAN, kanamycin; LIV, lividomycin; NEO, neomycin; PARO, paromomycin; SIS, sisomicin; TOB, tobramycin.

PreviousNext

Download PDF

Citation Tools

Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia

Aki Okazaki, Matthew B. Avison

Antimicrobial Agents and Chemotherapy Dec 2006, 51 (1) 359-360; DOI: 10.1128/AAC.00795-06

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Alerts

User Name *

Password *

Email *

Thank you for sharing this Antimicrobial Agents and Chemotherapy article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia

Message Subject (Your Name) has forwarded a page to you from Antimicrobial Agents and Chemotherapy

Message Body (Your Name) thought you would be interested in this article in Antimicrobial Agents and Chemotherapy.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia

Aki Okazaki, Matthew B. Avison

Antimicrobial Agents and Chemotherapy Dec 2006, 51 (1) 359-360; DOI: 10.1128/AAC.00795-06

Share This Article:

Top
Article
Figures & Data
Info & Metrics
PDF

KEYWORDS

aminoglycosides

Drug Resistance, Multiple, Bacterial

Kanamycin Kinase

Stenotrophomonas maltophilia

Cited By...

About

About AAC
Editor in Chief
Editorial Board
Policies
For Reviewers
For the Media
For Librarians
For Advertisers
Alerts
AAC Podcast
RSS
FAQ
Permissions
Journal Announcements

Authors

ASM Author Center
Submit a Manuscript
Article Types
Ethics
Contact Us

Follow #AACJournal

@ASMicrobiology

ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology.

About ASM | Contact Us | Press Room

ASM is a member of

American Society for Microbiology
1752 N St. NW
Washington, DC 20036
Phone: (202) 737-3600

Print ISSN: 0066-4804; Online ISSN: 1098-6596

Main menu

User menu

Search

Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia

Article Figures & Data

Tables

Citation Manager Formats

KEYWORDS

Related Articles

Cited By...