Mechanisms of Resistance

A Ser678Pro Substitution in Fks1p Confers Resistance to Echinocandin Drugs in Aspergillus fumigatus

Eleusa Maria F. Rocha, Guillermo Garcia-Effron, Steven Park, David S. Perlin
DOI: 10.1128/AAC.00917-07

Article Information

DOI 
https://doi.org/10.1128/AAC.00917-07
PubMed 
17724146
Published By 
American Society for Microbiology Journals
History 
  • Received July 13, 2007
  • Returned for modification July 21, 2007
  • Accepted August 20, 2007
  • Published online October 19, 2007.
Copyright & Usage 
Copyright © 2007 American Society for Microbiology

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Author Information

  1. Eleusa Maria F. Rocha,
  2. Guillermo Garcia-Effron,
  3. Steven Park and
  4. David S. Perlin*
  1. Public Health Research Institute and the Department of Microbiology and Molecular Genetics, UMDNJ-New Jersey Medical School, Newark, New Jersey 07103-3535
  • ↵* Corresponding author. Mailing address: PHRI, International Center for Public Health, 225 Warren St., Newark, NJ 07103. Phone: (973) 854-3200. Fax: (973) 854-3101. E-mail: perlinds{at}umdnj.edu
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KEYWORDS

Amino Acid Substitution
Aspergillus fumigatus
Drug Resistance, Fungal
echinocandins
Glucosyltransferases

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