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Susceptibility

Activity of Meropenem with and without Ciprofloxacin and Colistin against Pseudomonas aeruginosa and Acinetobacter baumannii

Glenn A. Pankuch, Gengrong Lin, Harald Seifert, Peter C. Appelbaum
Glenn A. Pankuch
1Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania 17033
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Gengrong Lin
1Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania 17033
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Harald Seifert
2University of Cologne, Cologne, Germany
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Peter C. Appelbaum
1Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania 17033
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  • For correspondence: pappelbaum@psu.edu
DOI: 10.1128/AAC.00689-07
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    FIG. 1.

    Time-kill synergy studies of meropenem combined with ciprofloxacin (A) and colistin (B) against 51 isolates of P. aeruginosa and of meropenem combined with ciprofloxacin (C) and colistin (D) against 41 and 51 strains of A. baumannii, respectively. In each pair of bars, the one on the left represents an additive effect and the one on the right represents synergy. **, Significantly higher percentage of organisms showing synergy (P < 0.001).

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Activity of Meropenem with and without Ciprofloxacin and Colistin against Pseudomonas aeruginosa and Acinetobacter baumannii
Glenn A. Pankuch, Gengrong Lin, Harald Seifert, Peter C. Appelbaum
Antimicrobial Agents and Chemotherapy Dec 2007, 52 (1) 333-336; DOI: 10.1128/AAC.00689-07

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Activity of Meropenem with and without Ciprofloxacin and Colistin against Pseudomonas aeruginosa and Acinetobacter baumannii
Glenn A. Pankuch, Gengrong Lin, Harald Seifert, Peter C. Appelbaum
Antimicrobial Agents and Chemotherapy Dec 2007, 52 (1) 333-336; DOI: 10.1128/AAC.00689-07
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KEYWORDS

Acinetobacter baumannii
Anti-Bacterial Agents
ciprofloxacin
colistin
Pseudomonas aeruginosa
Thienamycins

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