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Mechanisms of Resistance

An O-Phosphotransferase Catalyzes Phosphorylation of Hygromycin A in the Antibiotic-Producing Organism Streptomyces hygroscopicus

Vidya Dhote, Shuchi Gupta, Kevin A. Reynolds
Vidya Dhote
Department of Chemistry, Portland State University, Portland, Oregon 97201
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Shuchi Gupta
Department of Chemistry, Portland State University, Portland, Oregon 97201
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Kevin A. Reynolds
Department of Chemistry, Portland State University, Portland, Oregon 97201
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  • For correspondence: reynoldsk@pdx.edu
DOI: 10.1128/AAC.00157-08
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Article Information

DOI 
https://doi.org/10.1128/AAC.00157-08
PubMed 
18644964

Published By 
American Society for Microbiology Journals
History 
  • Received February 4, 2008
  • Returned for modification April 21, 2008
  • Accepted June 20, 2008
  • Published online September 24, 2008.

Copyright & Usage 
Copyright © 2008 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (July 21, 2008).
  • You are viewing the most recent version of this article.

Author Information

  1. Vidya Dhote,
  2. Shuchi Gupta and
  3. Kevin A. Reynolds*
  1. Department of Chemistry, Portland State University, Portland, Oregon 97201
  • ↵* Corresponding author. Mailing address: Department of Chemistry, Portland State University, PO Box 751, Portland, OR 97207-0751. Phone: (503) 725-3886. Fax: (503) 725-9525. E-mail: reynoldsk{at}pdx.edu

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An O-Phosphotransferase Catalyzes Phosphorylation of Hygromycin A in the Antibiotic-Producing Organism Streptomyces hygroscopicus
Vidya Dhote, Shuchi Gupta, Kevin A. Reynolds
Antimicrobial Agents and Chemotherapy Sep 2008, 52 (10) 3580-3588; DOI: 10.1128/AAC.00157-08

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An O-Phosphotransferase Catalyzes Phosphorylation of Hygromycin A in the Antibiotic-Producing Organism Streptomyces hygroscopicus
Vidya Dhote, Shuchi Gupta, Kevin A. Reynolds
Antimicrobial Agents and Chemotherapy Sep 2008, 52 (10) 3580-3588; DOI: 10.1128/AAC.00157-08
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KEYWORDS

Anti-Bacterial Agents
Hygromycin B
phosphotransferases
Streptomyces

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