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Experimental Therapeutics

Metronidazole Lacks Antibacterial Activity in Guinea Pigs Infected with Mycobacterium tuberculosis

Donald R. Hoff, Megan L. Caraway, Elizabeth J. Brooks, Emily R. Driver, Gavin J. Ryan, Charles A. Peloquin, Ian M. Orme, Randall J. Basaraba, Anne J. Lenaerts
Donald R. Hoff
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
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Megan L. Caraway
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
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Elizabeth J. Brooks
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
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Emily R. Driver
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
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Gavin J. Ryan
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
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Charles A. Peloquin
2Infectious Diseases Pharmacokinetics Laboratory, National Jewish Medical and Research Center, Denver, Colorado
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Ian M. Orme
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
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Randall J. Basaraba
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
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Anne J. Lenaerts
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
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  • For correspondence: lenaerts@colostate.edu
DOI: 10.1128/AAC.00196-08
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Article Information

DOI 
https://doi.org/10.1128/AAC.00196-08
PubMed 
18694944

Published By 
American Society for Microbiology Journals
History 
  • Received February 11, 2008
  • Returned for modification March 13, 2008
  • Accepted August 4, 2008
  • Published online October 23, 2008.

Copyright & Usage 
Copyright © 2008 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (August 11, 2008).
  • You are viewing the most recent version of this article.

Author Information

  1. Donald R. Hoff1,
  2. Megan L. Caraway1,
  3. Elizabeth J. Brooks1,
  4. Emily R. Driver1,
  5. Gavin J. Ryan1,
  6. Charles A. Peloquin2,
  7. Ian M. Orme1,
  8. Randall J. Basaraba1 and
  9. Anne J. Lenaerts1*
  1. 1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523
  2. 2Infectious Diseases Pharmacokinetics Laboratory, National Jewish Medical and Research Center, Denver, Colorado
  • ↵* Corresponding author. Mailing address: Department of Microbiology, Immunology and Pathology, Colorado State University, 200 West Lake Street, Fort Collins, CO 80523. Phone: (970) 491-3079. Fax: (970) 491-5125. E-mail: lenaerts{at}colostate.edu
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Metronidazole Lacks Antibacterial Activity in Guinea Pigs Infected with Mycobacterium tuberculosis
Donald R. Hoff, Megan L. Caraway, Elizabeth J. Brooks, Emily R. Driver, Gavin J. Ryan, Charles A. Peloquin, Ian M. Orme, Randall J. Basaraba, Anne J. Lenaerts
Antimicrobial Agents and Chemotherapy Oct 2008, 52 (11) 4137-4140; DOI: 10.1128/AAC.00196-08

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Metronidazole Lacks Antibacterial Activity in Guinea Pigs Infected with Mycobacterium tuberculosis
Donald R. Hoff, Megan L. Caraway, Elizabeth J. Brooks, Emily R. Driver, Gavin J. Ryan, Charles A. Peloquin, Ian M. Orme, Randall J. Basaraba, Anne J. Lenaerts
Antimicrobial Agents and Chemotherapy Oct 2008, 52 (11) 4137-4140; DOI: 10.1128/AAC.00196-08
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KEYWORDS

antitubercular agents
metronidazole
Tuberculosis, Pulmonary

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