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Pharmacology

P-Glycoprotein-Mediated Transport of Moxifloxacin in a Calu-3 Lung Epithelial Cell Model

Julien Brillault, Whocely Victor De Castro, Thomas Harnois, Alain Kitzis, Jean-Christophe Olivier, William Couet
Julien Brillault
1INSERM, ERI-23, 40 Avenue du Recteur Pineau, Poitiers, France
2Université de Poitiers, UFR Médecine-Pharmacie, 6 Rue de la Milétrie, Poitiers, France
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Whocely Victor De Castro
1INSERM, ERI-23, 40 Avenue du Recteur Pineau, Poitiers, France
2Université de Poitiers, UFR Médecine-Pharmacie, 6 Rue de la Milétrie, Poitiers, France
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Thomas Harnois
3Institut de Physiologie et de Biologie Cellulaire, CNRS UMR6187, Université de Poitiers, Poitiers, France
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Alain Kitzis
2Université de Poitiers, UFR Médecine-Pharmacie, 6 Rue de la Milétrie, Poitiers, France
3Institut de Physiologie et de Biologie Cellulaire, CNRS UMR6187, Université de Poitiers, Poitiers, France
4CHU Poitiers, 2 Rue de la Milétrie, Poitiers, France
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Jean-Christophe Olivier
1INSERM, ERI-23, 40 Avenue du Recteur Pineau, Poitiers, France
2Université de Poitiers, UFR Médecine-Pharmacie, 6 Rue de la Milétrie, Poitiers, France
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William Couet
1INSERM, ERI-23, 40 Avenue du Recteur Pineau, Poitiers, France
2Université de Poitiers, UFR Médecine-Pharmacie, 6 Rue de la Milétrie, Poitiers, France
4CHU Poitiers, 2 Rue de la Milétrie, Poitiers, France
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  • For correspondence: william.couet@univ-poitiers.fr
DOI: 10.1128/AAC.01253-08
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Article Information

DOI 
https://doi.org/10.1128/AAC.01253-08
PubMed 
19188390

Published By 
American Society for Microbiology Journals
History 
  • Received September 19, 2008
  • Returned for modification December 3, 2008
  • Accepted January 17, 2009
  • Published online March 19, 2009.

Copyright & Usage 
Copyright © 2009 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (February 02, 2009).
  • You are viewing the most recent version of this article.

Author Information

  1. Julien Brillault1,2,
  2. Whocely Victor De Castro1,2,
  3. Thomas Harnois3,
  4. Alain Kitzis2,3,4,
  5. Jean-Christophe Olivier1,2 and
  6. William Couet1,2,4*
  1. 1INSERM, ERI-23, 40 Avenue du Recteur Pineau, Poitiers, France
  2. 2Université de Poitiers, UFR Médecine-Pharmacie, 6 Rue de la Milétrie, Poitiers, France
  3. 3Institut de Physiologie et de Biologie Cellulaire, CNRS UMR6187, Université de Poitiers, Poitiers, France
  4. 4CHU Poitiers, 2 Rue de la Milétrie, Poitiers, France
  • ↵* Corresponding author. Mailing address: INSERM, ERI-23, Pôle Biologie Santé, 40 Avenue du Recteur Pineau, 86000 Poitiers, France. Phone: (33) 5 49 45 43 79. Fax: (33) 5 49 45 43 78. E-mail: william.couet{at}univ-poitiers.fr
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P-Glycoprotein-Mediated Transport of Moxifloxacin in a Calu-3 Lung Epithelial Cell Model
Julien Brillault, Whocely Victor De Castro, Thomas Harnois, Alain Kitzis, Jean-Christophe Olivier, William Couet
Antimicrobial Agents and Chemotherapy Mar 2009, 53 (4) 1457-1462; DOI: 10.1128/AAC.01253-08

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P-Glycoprotein-Mediated Transport of Moxifloxacin in a Calu-3 Lung Epithelial Cell Model
Julien Brillault, Whocely Victor De Castro, Thomas Harnois, Alain Kitzis, Jean-Christophe Olivier, William Couet
Antimicrobial Agents and Chemotherapy Mar 2009, 53 (4) 1457-1462; DOI: 10.1128/AAC.01253-08
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KEYWORDS

ATP Binding Cassette Transporter, Subfamily B, Member 1
anti-infective agents
Aza Compounds
lung
quinolines

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