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Mechanisms of Resistance

The Chromosomal Toxin Gene yafQ Is a Determinant of Multidrug Tolerance for Escherichia coli Growing in a Biofilm

Joe J. Harrison, William D. Wade, Sarah Akierman, Caterina Vacchi-Suzzi, Carol A. Stremick, Raymond J. Turner, Howard Ceri
Joe J. Harrison
1Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
2Biofilm Research Group, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
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William D. Wade
1Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
2Biofilm Research Group, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
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Sarah Akierman
1Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
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Caterina Vacchi-Suzzi
1Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
2Biofilm Research Group, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
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Carol A. Stremick
1Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
2Biofilm Research Group, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
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Raymond J. Turner
1Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
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  • For correspondence: turnerr@ucalgary.ca ceri@ucalgary.ca
Howard Ceri
1Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
2Biofilm Research Group, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
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  • For correspondence: turnerr@ucalgary.ca ceri@ucalgary.ca
DOI: 10.1128/AAC.00043-09
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Article Information

DOI 
https://doi.org/10.1128/AAC.00043-09
PubMed 
19307375

Published By 
American Society for Microbiology Journals
History 
  • Received January 12, 2009
  • Returned for modification February 28, 2009
  • Accepted March 14, 2009
  • Published online May 20, 2009.

Copyright & Usage 
Copyright © 2009 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (March 23, 2009).
  • You are viewing the most recent version of this article.

Author Information

  1. Joe J. Harrison1,2†,
  2. William D. Wade1,2,
  3. Sarah Akierman1,
  4. Caterina Vacchi-Suzzi1,2,
  5. Carol A. Stremick1,2,
  6. Raymond J. Turner1* and
  7. Howard Ceri1,2*
  1. 1Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
  2. 2Biofilm Research Group, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4
  • ↵† Present address: Department of Microbiology, University of Washington, Box 357242, 1959 NE Pacific Street, Seattle, WA 98195-7242.

  • ↵* Corresponding author. Mailing address: Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4. Phone for Raymond J. Turner: (403) 220-4308. Fax: (403) 289-9311. E-mail: turnerr{at}ucalgary.ca . Phone for Howard Ceri: (403) 220-6960. Fax: (403) 289-9311. E-mail: ceri{at}ucalgary.ca
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The Chromosomal Toxin Gene yafQ Is a Determinant of Multidrug Tolerance for Escherichia coli Growing in a Biofilm
Joe J. Harrison, William D. Wade, Sarah Akierman, Caterina Vacchi-Suzzi, Carol A. Stremick, Raymond J. Turner, Howard Ceri
Antimicrobial Agents and Chemotherapy May 2009, 53 (6) 2253-2258; DOI: 10.1128/AAC.00043-09

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The Chromosomal Toxin Gene yafQ Is a Determinant of Multidrug Tolerance for Escherichia coli Growing in a Biofilm
Joe J. Harrison, William D. Wade, Sarah Akierman, Caterina Vacchi-Suzzi, Carol A. Stremick, Raymond J. Turner, Howard Ceri
Antimicrobial Agents and Chemotherapy May 2009, 53 (6) 2253-2258; DOI: 10.1128/AAC.00043-09
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KEYWORDS

Bacterial Toxins
biofilms
Escherichia coli
Escherichia coli Proteins

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