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Table of Contents

January 2010; Volume 54,Issue 1

Instructions To Authors

  • Free
    INSTRUCTIONS TO AUTHORS
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Minireviews

  • Minireview
    Diversity, Epidemiology, and Genetics of Class D β-Lactamases
    Laurent Poirel, Thierry Naas, Patrice Nordmann

Mechanisms of Resistance

  • Mechanisms of Resistance
    Patients with Long-Term Oral Carriage Harbor High-Persister Mutants of Candida albicans
    Michael D. LaFleur, Qingguo Qi, Kim Lewis
  • Mechanisms of Resistance
    Molecular and Biochemical Characterization of the Natural Chromosome-Encoded Class A β-Lactamase from Pseudomonas luteola
    Benoît Doublet, Frédéric Robin, Isabelle Casin, Laëtitia Fabre, Anne Le Fleche, Richard Bonnet, François-Xavier Weill
  • Mechanisms of Resistance
    Metronidazole Resistance in Prevotella spp. and Description of a New nim Gene in Prevotella baroniae
    C. Alauzet, F. Mory, C. Teyssier, H. Hallage, J. P. Carlier, G. Grollier, A. Lozniewski
  • Mechanisms of Resistance
    Antimicrobial Resistance in Haemophilus influenzae Respiratory Tract Isolates in Korea: Results of a Nationwide Acute Respiratory Infections Surveillance
    Songmee Bae, Jaehoon Lee, Jaehwa Lee, Eunah Kim, Sunhwa Lee, Jaeyon Yu, Yeonho Kang
  • Mechanisms of Resistance
    Allelic Exchange and Mutant Selection Demonstrate that Common Clinical embCAB Gene Mutations Only Modestly Increase Resistance to Ethambutol in Mycobacterium tuberculosis
    Hassan Safi, Robert D. Fleischmann, Scott N. Peterson, Marcus B. Jones, Behnam Jarrahi, David Alland
  • Mechanisms of Resistance
    Novel Approach for Comparing the Abilities of Quinolones To Restrict the Emergence of Resistant Mutants during Quinolone Exposure
    Muhammad Malik, Gerard Hoatam, Kalyan Chavda, Robert J. Kerns, Karl Drlica
  • Mechanisms of Resistance
    Transfer of Plasmid-Mediated CTX-M-9 from Salmonella enterica Serotype Virchow to Enterobacteriaceae in Human Flora-Associated Rats Treated with Cefixime
    S. Faure, A. Perrin-Guyomard, J. M. Delmas, P. Chatre, M. Laurentie
  • Mechanisms of Resistance
    Klebsiella pneumoniae AcrAB Efflux Pump Contributes to Antimicrobial Resistance and Virulence
    Emma Padilla, Enrique Llobet, Antonio Doménech-Sánchez, Luis Martínez-Martínez, José Antonio Bengoechea, Sebastián Albertí
  • Mechanisms of Resistance
    Φm46.1, the Main Streptococcus pyogenes Element Carrying mef(A) and tet(O) Genes
    Andrea Brenciani, Alessandro Bacciaglia, Carla Vignaroli, Armanda Pugnaloni, Pietro E. Varaldo, Eleonora Giovanetti
  • Mechanisms of Resistance
    A Single Mutation in Enzyme I of the Sugar Phosphotransferase System Confers Penicillin Tolerance to Streptococcus gordonii
    A. Bizzini, J. M. Entenza, O. Michielin, I. Arnold, B. Erni, P. Moreillon
  • Mechanisms of Resistance
    Dispersal of Carbapenemase blaVIM-1 Gene Associated with Different Tn402 Variants, Mercury Transposons, and Conjugative Plasmids in Enterobacteriaceae and Pseudomonas aeruginosa
    Marta Tato, Teresa M. Coque, Fernando Baquero, Rafael Cantón
  • Mechanisms of Resistance
    Novel Ambler Class A Carbapenem-Hydrolyzing β-Lactamase from a Pseudomonas fluorescens Isolate from the Seine River, Paris, France
    Delphine Girlich, Laurent Poirel, Patrice Nordmann
  • Mechanisms of Resistance
    Screening and Quantification of the Expression of Antibiotic Resistance Genes in Acinetobacter baumannii with a Microarray
    Sébastien Coyne, Ghislaine Guigon, Patrice Courvalin, Bruno Périchon
  • Mechanisms of Resistance
    Molecular Epidemiology of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa Isolates from Norway and Sweden Shows Import of International Clones and Local Clonal Expansion
    Ørjan Samuelsen, Mark A. Toleman, Arnfinn Sundsfjord, Johan Rydberg, Truls M. Leegaard, Mats Walder, Astrid Lia, Trond E. Ranheim, Yashas Rajendra, Nils O. Hermansen, Timothy R. Walsh, Christian G. Giske
  • Mechanisms of Resistance
    An A643T Mutation in the Transcription Factor Upc2p Causes Constitutive ERG11 Upregulation and Increased Fluconazole Resistance in Candida albicans
    Clemens J. Heilmann, Sabrina Schneider, Katherine S. Barker, P. David Rogers, Joachim Morschhäuser
  • Mechanisms of Resistance
    Fitness Costs and Stability of a High-Level Ciprofloxacin Resistance Phenotype in Salmonella enterica Serotype Enteritidis: Reduced Infectivity Associated with Decreased Expression of Salmonella Pathogenicity Island 1 Genes
    Edel O'Regan, Teresa Quinn, Jonathan G. Frye, Jean-Marie Pagès, Steffen Porwollik, Paula J. Fedorka-Cray, Michael McClelland, Séamus Fanning
  • Mechanisms of Resistance
    Novel VIM Metallo-β-Lactamase Variant from Clinical Isolates of Enterobacteriaceae from Algeria
    Frédéric Robin, Nadjet Aggoune-Khinache, Julien Delmas, Malek Naim, Richard Bonnet
  • Mechanisms of Resistance
    VIM-19, a Metallo-β-Lactamase with Increased Carbapenemase Activity from Escherichia coli and Klebsiella pneumoniae
    Jose-Manuel Rodriguez-Martinez, Patrice Nordmann, Nicolas Fortineau, Laurent Poirel
  • Mechanisms of Resistance
    Molecular Correlates of High-Level Antifolate Resistance in Rwandan Children with Plasmodium falciparum Malaria
    Corine Karema, Mallika Imwong, Caterina I. Fanello, Kasia Stepniewska, Aline Uwimana, Supatchara Nakeesathit, Arjen Dondorp, Nicholas P. Day, Nicholas J. White
  • Mechanisms of Resistance
    Biologic Activities of the TolC-Like Protein of Neisseria meningitidis as Assessed by Functional Complementation in Escherichia coli
    Nazia Kamal, William M. Shafer
  • Mechanisms of Resistance
    Unusual Class 1 Integron Configuration Found in Salmonella Genomic Island 2 from Salmonella enterica Serovar Emek
    Neil L. Wilson, Ruth M. Hall
  • Mechanisms of Resistance
    BEL-2, an Extended-Spectrum β-Lactamase with Increased Activity toward Expanded-Spectrum Cephalosporins in Pseudomonas aeruginosa
    Laurent Poirel, Jean-Denis Docquier, Filomena De Luca, Annemie Verlinde, Louis Ide, Gian Maria Rossolini, Patrice Nordmann
  • Mechanisms of Resistance
    First Report of Extended-Spectrum-β-Lactamase-Producing Salmonella enterica Serovar Kentucky Isolated from Poultry in Ireland
    F. Boyle, D. Morris, J. O'Connor, N. DeLappe, J. Ward, M. Cormican
  • Mechanisms of Resistance
    Characteristics and Population Dynamics of Mosaic penA Allele-Containing Neisseria gonorrhoeae Isolates Collected in Sydney, Australia, in 2007-2008
    John W. Tapsall, Sanghamitra Ray, Athena Limnios
  • Mechanisms of Resistance
    Nonclonal Emergence of Colistin-Resistant Klebsiella pneumoniae Isolates from Blood Samples in South Korea
    Ji-Yoeun Suh, Jun Seong Son, Doo Ryeon Chung, Kyong Ran Peck, Kwan Soo Ko, Jae-Hoon Song
  • Mechanisms of Resistance
    Hydrolysis and Inhibition Profiles of β-Lactamases from Molecular Classes A to D with Doripenem, Imipenem, and Meropenem
    Anne Marie Queenan, Wenchi Shang, Robert Flamm, Karen Bush
  • Mechanisms of Resistance
    Phenotypic and Genotypic Characterization of Enterobacteriaceae with Decreased Susceptibility to Carbapenems: Results from Large Hospital-Based Surveillance Studies in China
    Qiwen Yang, Hui Wang, Hongli Sun, Hongbin Chen, Yingchun Xu, Minjun Chen

Pharmacology

  • Pharmacology
    Pharmacokinetics of Artemether-Lumefantrine and Artesunate-Amodiaquine in Children in Kampala, Uganda
    Julia Mwesigwa, Sunil Parikh, Bryan McGee, Polina German, Troy Drysdale, Joan N. Kalyango, Tamara D. Clark, Grant Dorsey, Niklas Lindegardh, Anna Annerberg, Philip J. Rosenthal, Moses R. Kamya, Francesca Aweeka
  • Pharmacology
    Factors Influencing Pharmacokinetics of Prophylactic Posaconazole in Patients Undergoing Allogeneic Stem Cell Transplantation
    V. Kohl, C. Müller, O. A. Cornely, K. Abduljalil, U. Fuhr, J. J. Vehreschild, C. Scheid, M. Hallek, M. J. G. T. Rüping
  • Pharmacology
    Safety and Pharmacokinetics of Urtoxazumab, a Humanized Monoclonal Antibody, against Shiga-Like Toxin 2 in Healthy Adults and in Pediatric Patients Infected with Shiga-Like Toxin-Producing Escherichia coli
    Eduardo L. López, Maria M. Contrini, Eduardo Glatstein, Silvia González Ayala, Roberto Santoro, Daniel Allende, Gustavo Ezcurra, Eduardo Teplitz, Tamotsu Koyama, Yoichi Matsumoto, Hiroaki Sato, Kazuaki Sakai, Satoru Hoshide, Keiji Komoriya, Takuya Morita, Ronald Harning, Sheldon Brookman
  • Pharmacology
    Pharmacokinetics and Safety of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor, in Healthy Volunteers
    Sherene Min, Ivy Song, Julie Borland, Shuguang Chen, Yu Lou, Tamio Fujiwara, Stephen C. Piscitelli
  • Pharmacology
    Pharmacokinetic Properties of Azithromycin in Pregnancy
    Sam Salman, Stephen J. Rogerson, Kay Kose, Susan Griffin, Servina Gomorai, Francesca Baiwog, Josephine Winmai, Josin Kandai, Harin A. Karunajeewa, Sean J. O'Halloran, Peter Siba, Kenneth F. Ilett, Ivo Mueller, Timothy M. E. Davis
  • Pharmacology
    Pharmacometrics-Based Dose Selection of Levofloxacin as a Treatment for Postexposure Inhalational Anthrax in Children
    Fang Li, Partha Nandy, Shuchean Chien, Gary J. Noel, Christoffer W. Tornoe
  • Pharmacology
    Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Nemonoxacin (TG-873870), a Novel Potent Broad-Spectrum Nonfluorinated Quinolone, in Healthy Volunteers
    Luke Lin, Li-Wen Chang, Cheng-Yuan Tsai, Ching-Hung Hsu, David T. Chung, William S. Aronstein, Funmi Ajayi, Barbara Kuzmak, Robert A. Lyon
  • Pharmacology
    Multiple-Dose Safety, Tolerability, and Pharmacokinetics of Oral Nemonoxacin (TG-873870) in Healthy Volunteers
    David T. Chung, Cheng-Yuan Tsai, Shu-Jen Chen, Li-Wen Chang, Chi-Hsin R. King, Ching-Hung Hsu, Kit-Mui Chiu, Hao-Chen Tan, Yu-Ting Chang, Ming-Chu Hsu
  • Pharmacology
    Identification of Optimal Renal Dosage Adjustments for Traditional and Extended-Infusion Piperacillin-Tazobactam Dosing Regimens in Hospitalized Patients
    N. Patel, M. H. Scheetz, G. L. Drusano, T. P. Lodise
  • Pharmacology
    Absorption, Pharmacokinetics, and Safety of Triclosan after Dermal Administration
    Christian Queckenberg, Jürgen Meins, Bertil Wachall, Oxana Doroshyenko, Dorota Tomalik-Scharte, Bärbel Bastian, Mona Abdel-Tawab, Uwe Fuhr

Antiviral Agents

  • Antiviral Agents
    Factors Associated with Virological Response to Etravirine in Nonnucleoside Reverse Transcriptase Inhibitor-Experienced HIV-1-Infected Patients
    Anne-Genevieve Marcelin, Philippe Flandre, Diane Descamps, Laurence Morand-Joubert, Charlotte Charpentier, Jacques Izopet, Mary-Anne Trabaud, Henia Saoudin, Constance Delaugerre, Catherine Tamalet, Jacqueline Cottalorda, Magali Bouvier-Alias, Dominique Bettinger, Georges Dos Santos, Annick Ruffault, Chakib Alloui, Cecile Henquell, Sylvie Rogez, Francis Barin, Anne Signori-Schmuck, Sophie Vallet, Bernard Masquelier, Vincent Calvez
    and and the ANRS AC11 Resistance Study Group
  • Antiviral Agents
    Inducible APOBEC3G-Vif Double Stable Cell Line as a High-Throughput Screening Platform To Identify Antiviral Compounds
    Boris Nowotny, Thomas Schneider, Gabriele Pradel, Tanja Schirmeister, Axel Rethwilm, Marc Kirschner
  • Antiviral Agents
    Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice
    Donald F. Smee, Brett L. Hurst, Min-Hui Wong, Kevin W. Bailey, E. Bart Tarbet, John D. Morrey, Yousuke Furuta
  • Antiviral Agents
    Long-Lasting Enfuvirtide Carrier Pentasaccharide Conjugates with Potent Anti-Human Immunodeficiency Virus Type 1 Activity
    Thierry Huet, Olivier Kerbarh, Dominique Schols, Pascal Clayette, Cécile Gauchet, Guy Dubreucq, Loïc Vincent, Heidi Bompais, Romain Mazinghien, Olivier Querolle, Arnaud Salvador, Jérôme Lemoine, Bruno Lucidi, Jan Balzarini, Maurice Petitou
  • Antiviral Agents
    An Albumin-Conjugated Peptide Exhibits Potent Anti-HIV Activity and Long In Vivo Half-Life
    Dong Xie, Cheng Yao, Li Wang, Wenjie Min, Jiahong Xu, Jiahai Xiao, Mingxian Huang, Bo Chen, Bin Liu, Xiaolin Li, He Jiang
  • Antiviral Agents
    A Novel Class of meso-Tetrakis-Porphyrin Derivatives Exhibits Potent Activities against Hepatitis C Virus Genotype 1b Replicons In Vitro
    Yao Cheng, Lun K. Tsou, Jianfeng Cai, Toshihiro Aya, Ginger E. Dutschman, Elizabeth A. Gullen, Susan P. Grill, Annie Pei-Chun Chen, Brett D. Lindenbach, Andrew D. Hamilton, Yung-chi Cheng
  • Antiviral Agents
    Mitochondrial DNA Depletion and Respiratory Chain Activity in Primary Human Subcutaneous Adipocytes Treated with Nucleoside Analogue Reverse Transcriptase Inhibitors
    Metodi V. Stankov, Thomas Lücke, Anibh M. Das, Reinhold E. Schmidt, Georg M. N. Behrens
  • Antiviral Agents
    MK-7009, a Potent and Selective Inhibitor of Hepatitis C Virus NS3/4A Protease
    Nigel J. Liverton, Steven S. Carroll, Jillian DiMuzio, Christine Fandozzi, Donald J. Graham, Daria Hazuda, M. Katherine Holloway, Steven W. Ludmerer, John A. McCauley, Charles J. McIntyre, David B. Olsen, Michael T. Rudd, Mark Stahlhut, Joseph P. Vacca
  • Antiviral Agents
    Cellular Pharmacology of the Anti-Hepatitis B Virus Agent β-l-2′,3′-Didehydro-2′,3′-Dideoxy-N4-Hydroxycytidine: Relevance for Activation in HepG2 Cells
    E. Matthes, H. Bünger
  • Antiviral Agents
    Inhibition of B Virus (Macacine herpesvirus 1) by Conventional and Experimental Antiviral Compounds
    P. W. Krug, R. F. Schinazi, J. K. Hilliard
  • Antiviral Agents
    Impact of Y143 HIV-1 Integrase Mutations on Resistance to Raltegravir In Vitro and In Vivo
    Olivier Delelis, Sylvain Thierry, Frédéric Subra, Françoise Simon, Isabelle Malet, Chakib Alloui, Sophie Sayon, Vincent Calvez, Eric Deprez, Anne-Geneviève Marcelin, Luba Tchertanov, Jean-François Mouscadet

Clinical Therapeutics

  • Clinical Therapeutics
    Continuous Clindamycin Infusion, an Innovative Approach to Treating Bone and Joint Infections
    Valérie Zeller, Arnaud Dzeing-Ella, Marie-Dominique Kitzis, Jean-Marc Ziza, Patrick Mamoudy, Nicole Desplaces
  • Clinical Therapeutics
    Attributable Hospital Cost and Length of Stay Associated with Health Care-Associated Infections Caused by Antibiotic-Resistant Gram-Negative Bacteria
    Patrick D. Mauldin, Cassandra D. Salgado, Ida Solhøj Hansen, Darshana T. Durup, John A. Bosso
  • Clinical Therapeutics
    Effect of Antifungal Therapy Timing on Mortality in Cancer Patients with Candidemia
    Ying Taur, Nina Cohen, Sarah Dubnow, Alla Paskovaty, Susan K. Seo

Susceptibility

  • Susceptibility
    Prevalence and Clonal Characterization of Streptococcus pyogenes Clinical Isolates with Reduced Fluoroquinolone Susceptibility in Spain
    Milagrosa Montes, Esther Tamayo, Beatriz Orden, Julián Larruskain, Emilio Perez-Trallero
  • Susceptibility
    In Vitro Activity of Gallium Maltolate against Staphylococci in Logarithmic, Stationary, and Biofilm Growth Phases: Comparison of Conventional and Calorimetric Susceptibility Testing Methods
    Daniela Baldoni, Andrea Steinhuber, Werner Zimmerli, Andrej Trampuz
  • Susceptibility
    In Vitro Activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with Defined Macrolide Resistance Mechanisms
    Pamela McGhee, Catherine Clark, Klaudia M. Kosowska-Shick, Kensuke Nagai, Bonifacio Dewasse, Linda Beachel, Peter C. Appelbaum
  • Susceptibility
    Echinocandin Susceptibility Testing of Candida Species: Comparison of EUCAST EDef 7.1, CLSI M27-A3, Etest, Disk Diffusion, and Agar Dilution Methods with RPMI and IsoSensitest Media
    Maiken Cavling Arendrup, Guillermo Garcia-Effron, Cornelia Lass-Flörl, Alicia Gomez Lopez, Juan-Luis Rodriguez-Tudela, Manuel Cuenca-Estrella, David S. Perlin
  • Susceptibility
    Assessment of the In Vitro Kinetic Activity of Caspofungin against Candida glabrata
    V. Nagappan, D. Boikov, J. A. Vazquez
  • Susceptibility
    In Vitro Activity of Fosfomycin against blaKPC-Containing Klebsiella pneumoniae Isolates, Including Those Nonsusceptible to Tigecycline and/or Colistin
    Andrea Endimiani, Gopi Patel, Kristine M. Hujer, Mahesh Swaminathan, Federico Perez, Louis B. Rice, Michael R. Jacobs, Robert A. Bonomo
  • Susceptibility
    In Vitro Activity of Thimerosal against Ocular Pathogenic Fungi
    Yan Xu, Guangren Pang, Dongqing Zhao, Chuanwen Gao, Lutan Zhou, Shengtao Sun, Bingliang Wang
  • Susceptibility
    In Vitro Activity of Mirincamycin (U24729A) against Plasmodium falciparum Isolates from Gabon
    Jana Held, Richard Westerman, Peter G. Kremsner, Benjamin Mordmüller
  • Susceptibility
    Escherichia coli Sequence Type ST131 as an Emerging Fluoroquinolone-Resistant Uropathogen among Renal Transplant Recipients
    James R. Johnson, Brian Johnston, Connie Clabots, Michael A. Kuskowski, Swaroop Pendyala, Chitrita DebRoy, Bogdan Nowicki, James Rice
  • Susceptibility
    In Vitro Potency of CXA-101, a Novel Cephalosporin, against Pseudomonas aeruginosa Displaying Various Resistance Phenotypes, Including Multidrug Resistance
    Catharine C. Bulik, Henry Christensen, David P. Nicolau

Mechanisms of Action

  • Mechanisms of Action: Physiological Effects
    Clindamycin-Induced CovS-Mediated Regulation of the Production of Virulent Exoproteins Streptolysin O, NAD Glycohydrolase, and Streptokinase in Streptococcus pyogenes
    Masaaki Minami, Takuya Kamimura, Masanori Isaka, Ichiro Tatsuno, Michio Ohta, Tadao Hasegawa
  • Mechanisms of Action: Physiological Effects
    Mapping Simocyclinone D8 Interaction with DNA Gyrase: Evidence for a New Binding Site on GyrB
    C. Sissi, E. Vazquez, A. Chemello, L. A. Mitchenall, A. Maxwell, M. Palumbo
  • Mechanisms of Action: Physiological Effects
    Structure of the Heme Biosynthetic Pseudomonas aeruginosa Porphobilinogen Synthase in Complex with the Antibiotic Alaremycin
    Ilka U. Heinemann, Claudia Schulz, Wolf-Dieter Schubert, Dirk W. Heinz, Yang-G. Wang, Yuichi Kobayashi, Yuuki Awa, Masaaki Wachi, Dieter Jahn, Martina Jahn
  • Mechanisms of Action: Physiological Effects
    Isolation and Characterization of Two Members of the Siderophore-Microcin Family, Microcins M and H47
    Gaëlle Vassiliadis, Delphine Destoumieux-Garzón, Carine Lombard, Sylvie Rebuffat, Jean Peduzzi
  • Mechanisms of Action: Physiological Effects
    Influence of Tigecycline on Expression of Virulence Factors in Biofilm-Associated Cells of Methicillin-Resistant Staphylococcus aureus
    Karen Smith, Katherine A. Gould, Gordon Ramage, Curtis G. Gemmell, Jason Hinds, Sue Lang
  • Mechanisms of Action: Physiological Effects
    Pretreatment of Epithelial Cells with Rifaximin Alters Bacterial Attachment and Internalization Profiles
    Eric L. Brown, Qiong Xue, Zhi-Dong Jiang, Yi Xu, Herbert L. DuPont
  • Mechanisms of Action: Physiological Effects
    Structure-Microbicidal Activity Relationship of Synthetic Fragments Derived from the Antibacterial α-Helix of Human Lactoferrin
    L. Håversen, N. Kondori, L. Baltzer, L. Å. Hanson, G. T. Dolphin, K. Dunér, I. Mattsby-Baltzer
  • Mechanisms of Action: Physiological Effects
    Generic and Specific Adaptive Responses of Streptococcus pneumoniae to Challenge with Three Distinct Antimicrobial Peptides, Bacitracin, LL-37, and Nisin
    Joanna A. Majchrzykiewicz, Oscar P. Kuipers, Jetta J. E. Bijlsma
  • Mechanisms of Action: Physiological Effects
    Relative Contributions of Active Mediated Transport and Passive Diffusion of Fluoroquinolones with Various Lipophilicities in a Calu-3 Lung Epithelial Cell Model
    Julien Brillault, Whocely Victor De Castro, William Couet

Experimental Therapeutics

  • Experimental Therapeutics
    In Vivo Activity of Ceftobiprole in Murine Skin Infections Due to Staphylococcus aureus and Pseudomonas aeruginosa
    Jeffrey Fernandez, Jamese J. Hilliard, Darren Abbanat, Wenyan Zhang, John L. Melton, Colleen M. Santoro, Robert K. Flamm, Karen Bush
  • Experimental Therapeutics
    In Vitro Pharmacodynamics of Levofloxacin and Other Aerosolized Antibiotics under Multiple Conditions Relevant to Chronic Pulmonary Infection in Cystic Fibrosis
    Paula King, Olga Lomovskaya, David C. Griffith, Jane L. Burns, Michael N. Dudley
  • Experimental Therapeutics
    In Vitro and In Vivo Efficacies of Teicoplanin-Loaded Calcium Sulfate for Treatment of Chronic Methicillin-Resistant Staphylococcus aureus Osteomyelitis
    Wei-Tao Jia, Shi-Hua Luo, Chang-Qing Zhang, Jian-Qiang Wang
  • Experimental Therapeutics
    Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model
    Oyebode Olakanmi, John S. Gunn, Shengchang Su, Shilpa Soni, Daniel J. Hassett, Bradley E. Britigan
  • Experimental Therapeutics
    Slow Release of Nitric Oxide from Charged Catheters and Its Effect on Biofilm Formation by Escherichia coli
    Gilly Regev-Shoshani, Mary Ko, Chris Miller, Yossef Av-Gay
  • Experimental Therapeutics
    Prevention and Treatment of Staphylococcus aureus Pneumonia with a β-Cyclodextrin Derivative
    Brook E. Ragle, Vladimir A. Karginov, Juliane Bubeck Wardenburg
  • Experimental Therapeutics
    Chip Calorimetry for Fast and Reliable Evaluation of Bactericidal and Bacteriostatic Treatments of Biofilms
    F. Buchholz, A. Wolf, J. Lerchner, F. Mertens, H. Harms, T. Maskow
  • Experimental Therapeutics
    Bacteriophage Cocktail for the Prevention of Biofilm Formation by Pseudomonas aeruginosa on Catheters in an In Vitro Model System
    Weiling Fu, Terri Forster, Oren Mayer, John J. Curtin, Susan M. Lehman, Rodney M. Donlan
  • Experimental Therapeutics
    Antifungal Activity of Colistin against Mucorales Species In Vitro and in a Murine Model of Rhizopus oryzae Pulmonary Infection
    Ronen Ben-Ami, Russell E. Lewis, Jeffrey Tarrand, Konstantinos Leventakos, Dimitrios P. Kontoyiannis
  • Experimental Therapeutics
    Comparative Efficacies of Two Antimony Regimens To Treat Leishmania braziliensis-Induced Cutaneous Leishmaniasis in Rhesus Macaques (Macaca mulatta)
    G. Grimaldi, R. Porrozzi, K. Friedrich, A. Teva, R. S. Marchevsky, F. Vieira, N. Miekeley, F. J. R. Paumgartten
  • Experimental Therapeutics
    In Vitro and In Vivo Activities of 1-Hydroxy-2-Alkyl-4(1H)Quinolone Derivatives against Toxoplasma gondii
    Lara Liv Bajohr, Ling Ma, Christian Platte, Oliver Liesenfeld, Lutz F. Tietze, Uwe Groß, Wolfgang Bohne
  • Experimental Therapeutics
    Efficacy of Posaconazole in a Murine Disseminated Infection by Candida tropicalis
    Marçal Mariné, F. Javier Pastor, Josep Guarro
  • Experimental Therapeutics
    In Vivo Activities of Recombinant Divercin V41 and Its Structural Variants against Listeria monocytogenes
    Jitka Rihakova, Jean-Michel Cappelier, Isabelle Hue, Katerina Demnerova, Michel Fédérighi, Hervé Prévost, Djamel Drider

Analytical Procedures

  • Analytical Procedures
    Method for Screening Compounds That Influence Virulence Gene Expression in Staphylococcus aureus
    Anita Nielsen, Kristian F. Nielsen, Dorte Frees, Thomas O. Larsen, Hanne Ingmer

Letters

  • LETTERS TO THE EDITOR
    First Isolation of the blaOXA-23 Carbapenemase Gene from an Environmental Acinetobacter baumannii Isolate
    Delphine Girlich, Laurent Poirel, Patrice Nordmann
  • LETTERS TO THE EDITOR
    SmQnr Contributes to Intrinsic Resistance to Quinolones in Stenotrophomonas maltophilia
    María B. Sánchez, José L. Martínez
  • LETTERS TO THE EDITOR
    First Report of the Metallo-β-Lactamase SPM-1 in Europe
    Allaaeddin El Salabi, Mark A. Toleman, Janis Weeks, Thomas Bruderer, Reno Frei, Timothy R. Walsh
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Antimicrobial Agents and Chemotherapy: 54 (1)

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volume 54, issue 1
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  • Instructions To Authors
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  • Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity Against SARS-CoV-2
  • Mechanism-of-Action Classification of Antibiotics by Global Transcriptome Profiling
  • Fact versus Fiction: a Review of the Evidence behind Alcohol and Antibiotic Interactions
  • Povidone Iodine: Properties, Mechanisms of Action, and Role in Infection Control and Staphylococcus aureus Decolonization
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