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Susceptibility

Strong In Vitro Activities of Two New Rifabutin Analogs against Multidrug-Resistant Mycobacterium tuberculosis

Ana-Belén García, Juan J. Palacios, María-Jesús Ruiz, José Barluenga, Fernando Aznar, María-Paz Cabal, José María García, Natalia Díaz
Ana-Belén García
1Instituto Universitario de Química Organometálica Enrique Moles, Unidad Asociada al C.S.I.C., Universidad de Oviedo, c/ Julián Clavería 8, 33006 Oviedo, Spain
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Juan J. Palacios
2Unidad de Referencia Regional de Micobacterias, Hospital Universitario Central de Asturias, c/ Doctor Bellmunt s/n, 33006 Oviedo, Spain
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María-Jesús Ruiz
3Servicio de Microbiología Clínica, Hospital General Universitario Gregorio Marañón, c/ Dr. Esquerdo 46, 28007 Madrid, Spain
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José Barluenga
1Instituto Universitario de Química Organometálica Enrique Moles, Unidad Asociada al C.S.I.C., Universidad de Oviedo, c/ Julián Clavería 8, 33006 Oviedo, Spain
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Fernando Aznar
1Instituto Universitario de Química Organometálica Enrique Moles, Unidad Asociada al C.S.I.C., Universidad de Oviedo, c/ Julián Clavería 8, 33006 Oviedo, Spain
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María-Paz Cabal
1Instituto Universitario de Química Organometálica Enrique Moles, Unidad Asociada al C.S.I.C., Universidad de Oviedo, c/ Julián Clavería 8, 33006 Oviedo, Spain
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  • For correspondence: pcabal@uniovi.es
José María García
4Servicio de Neumología, Hospital San Agustín, Camino de Heros 4, 33400 Avilés, Spain
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Natalia Díaz
5Departamento de Química Física y Analítica, Universidad de Oviedo, c/ Julián Clavería 8, 33006 Oviedo, Spain
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DOI: 10.1128/AAC.00149-10
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Article Information

DOI 
https://doi.org/10.1128/AAC.00149-10
PubMed 
20855731

Published By 
American Society for Microbiology Journals
History 
  • Received February 2, 2010
  • Returned for modification April 4, 2010
  • Accepted August 29, 2010
  • Published online November 12, 2010.

Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (September 20, 2010).
  • You are viewing the most recent version of this article.

Author Information

  1. Ana-Belén García1,
  2. Juan J. Palacios2,
  3. María-Jesús Ruiz3,
  4. José Barluenga1,
  5. Fernando Aznar1,
  6. María-Paz Cabal1*,
  7. José María García4 and
  8. Natalia Díaz5
  1. 1Instituto Universitario de Química Organometálica Enrique Moles, Unidad Asociada al C.S.I.C., Universidad de Oviedo, c/ Julián Clavería 8, 33006 Oviedo, Spain
  2. 2Unidad de Referencia Regional de Micobacterias, Hospital Universitario Central de Asturias, c/ Doctor Bellmunt s/n, 33006 Oviedo, Spain
  3. 3Servicio de Microbiología Clínica, Hospital General Universitario Gregorio Marañón, c/ Dr. Esquerdo 46, 28007 Madrid, Spain
  4. 4Servicio de Neumología, Hospital San Agustín, Camino de Heros 4, 33400 Avilés, Spain
  5. 5Departamento de Química Física y Analítica, Universidad de Oviedo, c/ Julián Clavería 8, 33006 Oviedo, Spain
  • ↵* Corresponding author. Mailing address: Instituto Universitario de Química Organometálica Enrique Moles, Unidad Asociada al C.S.I.C., Universidad de Oviedo, c/ Julián Clavería 8, 33006 Oviedo, Spain. Phone: 985102990. Fax: 985103446. E-mail: pcabal{at}uniovi.es
  • † Supplemental material for this article may be found at http://aac.asm.org/ .

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Strong In Vitro Activities of Two New Rifabutin Analogs against Multidrug-Resistant Mycobacterium tuberculosis
Ana-Belén García, Juan J. Palacios, María-Jesús Ruiz, José Barluenga, Fernando Aznar, María-Paz Cabal, José María García, Natalia Díaz
Antimicrobial Agents and Chemotherapy Nov 2010, 54 (12) 5363-5365; DOI: 10.1128/AAC.00149-10

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Strong In Vitro Activities of Two New Rifabutin Analogs against Multidrug-Resistant Mycobacterium tuberculosis
Ana-Belén García, Juan J. Palacios, María-Jesús Ruiz, José Barluenga, Fernando Aznar, María-Paz Cabal, José María García, Natalia Díaz
Antimicrobial Agents and Chemotherapy Nov 2010, 54 (12) 5363-5365; DOI: 10.1128/AAC.00149-10
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KEYWORDS

Antibiotics, Antitubercular
Drug Resistance, Multiple, Bacterial
Mycobacterium tuberculosis
rifabutin

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