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Experimental Therapeutics

Immunotherapy Markedly Increases the Effectiveness of Antimicrobial Therapy for Treatment of Burkholderia pseudomallei Infection

Katie L. Propst, Ryan M. Troyer, Lisa M. Kellihan, Herbert P. Schweizer, Steven W. Dow
Katie L. Propst
Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Disease Research, Colorado State University, Ft. Collins, Colorado 80523
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Ryan M. Troyer
Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Disease Research, Colorado State University, Ft. Collins, Colorado 80523
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Lisa M. Kellihan
Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Disease Research, Colorado State University, Ft. Collins, Colorado 80523
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Herbert P. Schweizer
Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Disease Research, Colorado State University, Ft. Collins, Colorado 80523
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Steven W. Dow
Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Disease Research, Colorado State University, Ft. Collins, Colorado 80523
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  • For correspondence: sdow@colostate.edu
DOI: 10.1128/AAC.01513-09
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Article Information

DOI 
https://doi.org/10.1128/AAC.01513-09
PubMed 
20176901

Published By 
American Society for Microbiology Journals
History 
  • Received October 22, 2009
  • Returned for modification December 7, 2009
  • Accepted February 11, 2010
  • Published online April 19, 2010.

Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (February 22, 2010).
  • You are viewing the most recent version of this article.

Author Information

  1. Katie L. Propst‡,
  2. Ryan M. Troyer‡,
  3. Lisa M. Kellihan,
  4. Herbert P. Schweizer and
  5. Steven W. Dow*
  1. Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Disease Research, Colorado State University, Ft. Collins, Colorado 80523
  • ↵‡ Both of these authors contributed equally to this work.

  • ↵* Corresponding author. Mailing address: Department of Microbiology, Immunology, and Pathology, Colorado State University, 1619 Campus Delivery, Ft. Collins, CO 80523. Phone: (970) 491-6144. Fax: (970) 491-0603. E-mail: sdow{at}colostate.edu
  • † Supplemental material for this article may be found at http://aac.asm.org/ .

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Immunotherapy Markedly Increases the Effectiveness of Antimicrobial Therapy for Treatment of Burkholderia pseudomallei Infection
Katie L. Propst, Ryan M. Troyer, Lisa M. Kellihan, Herbert P. Schweizer, Steven W. Dow
Antimicrobial Agents and Chemotherapy Apr 2010, 54 (5) 1785-1792; DOI: 10.1128/AAC.01513-09

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Immunotherapy Markedly Increases the Effectiveness of Antimicrobial Therapy for Treatment of Burkholderia pseudomallei Infection
Katie L. Propst, Ryan M. Troyer, Lisa M. Kellihan, Herbert P. Schweizer, Steven W. Dow
Antimicrobial Agents and Chemotherapy Apr 2010, 54 (5) 1785-1792; DOI: 10.1128/AAC.01513-09
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KEYWORDS

Anti-Bacterial Agents
Burkholderia pseudomallei
ceftazidime
Interferon-gamma
melioidosis

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