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Mechanisms of Resistance

Novel FKS Mutations Associated with Echinocandin Resistance in Candida Species

Guillermo Garcia-Effron, Daniel Joseph Chua, Jon Rupert Tomada, Joseph DiPersio, David S. Perlin, Mahmoud Ghannoum, Hector Bonilla
Guillermo Garcia-Effron
1Public Health Research Institute, Newark, New Jersey
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Daniel Joseph Chua
2Summa Health Systems, Akron, Ohio
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Jon Rupert Tomada
2Summa Health Systems, Akron, Ohio
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Joseph DiPersio
2Summa Health Systems, Akron, Ohio
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David S. Perlin
1Public Health Research Institute, Newark, New Jersey
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Mahmoud Ghannoum
3University Hospitals, Case Western Reserve, Cleveland, Ohio
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Hector Bonilla
2Summa Health Systems, Akron, Ohio
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  • For correspondence: Bonillah@summa-health.org
DOI: 10.1128/AAC.00998-09
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Article Information

DOI 
https://doi.org/10.1128/AAC.00998-09
PubMed 
20145084

Published By 
American Society for Microbiology Journals
History 
  • Received July 16, 2009
  • Returned for modification September 23, 2009
  • Accepted January 31, 2010
  • Published online April 19, 2010.

Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (February 09, 2010).
  • You are viewing the most recent version of this article.

Author Information

  1. Guillermo Garcia-Effron1,
  2. Daniel Joseph Chua2,
  3. Jon Rupert Tomada2,
  4. Joseph DiPersio2,
  5. David S. Perlin1,
  6. Mahmoud Ghannoum3 and
  7. Hector Bonilla2*
  1. 1Public Health Research Institute, Newark, New Jersey
  2. 2Summa Health Systems, Akron, Ohio
  3. 3University Hospitals, Case Western Reserve, Cleveland, Ohio
  • ↵* Corresponding author. Mailing address: Summa Health Systems, Akron, OH 44305. Phone: (330) 375-3894. Fax: (330) 375-6680. E-mail: Bonillah{at}summa-health.org
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Novel FKS Mutations Associated with Echinocandin Resistance in Candida Species
Guillermo Garcia-Effron, Daniel Joseph Chua, Jon Rupert Tomada, Joseph DiPersio, David S. Perlin, Mahmoud Ghannoum, Hector Bonilla
Antimicrobial Agents and Chemotherapy Apr 2010, 54 (5) 2225-2227; DOI: 10.1128/AAC.00998-09

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Novel FKS Mutations Associated with Echinocandin Resistance in Candida Species
Guillermo Garcia-Effron, Daniel Joseph Chua, Jon Rupert Tomada, Joseph DiPersio, David S. Perlin, Mahmoud Ghannoum, Hector Bonilla
Antimicrobial Agents and Chemotherapy Apr 2010, 54 (5) 2225-2227; DOI: 10.1128/AAC.00998-09
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  • Top
  • Article
    • ABSTRACT
    • Case 1 (C. tropicalis strain CT-C1).
    • Case 2 (C. glabrata strain CG-C2).
    • Case 3 (C. glabrata strain CG-C3).
    • Characterization of clinical isolates.
    • ACKNOWLEDGMENTS
    • FOOTNOTES
    • REFERENCES
  • Figures & Data
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  • PDF

KEYWORDS

antifungal agents
Candida glabrata
Candida tropicalis
candidiasis
echinocandins
Glucosyltransferases

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