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Mechanisms of Resistance

Daptomycin-Oxacillin Combinations in Treatment of Experimental Endocarditis Caused by Daptomycin-Nonsusceptible Strains of Methicillin-Resistant Staphylococcus aureus with Evolving Oxacillin Susceptibility (the “Seesaw Effect”)

Soo-Jin Yang, Yan Q. Xiong, Susan Boyle-Vavra, Robert Daum, Tiffanny Jones, Arnold S. Bayer
Soo-Jin Yang
1Los Angeles Biomedical Research Institute, Torrance, California
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  • For correspondence: sjyang@labiomed.org
Yan Q. Xiong
1Los Angeles Biomedical Research Institute, Torrance, California
2David Geffen School of Medicine, UCLA, Los Angeles, California
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Susan Boyle-Vavra
3Department of Pediatrics, University of Chicago, Chicago, Illinois
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Robert Daum
3Department of Pediatrics, University of Chicago, Chicago, Illinois
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Tiffanny Jones
1Los Angeles Biomedical Research Institute, Torrance, California
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Arnold S. Bayer
1Los Angeles Biomedical Research Institute, Torrance, California
2David Geffen School of Medicine, UCLA, Los Angeles, California
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DOI: 10.1128/AAC.00487-10
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Article Information

DOI 
https://doi.org/10.1128/AAC.00487-10
PubMed 
20547804

Published By 
American Society for Microbiology Journals
History 
  • Received April 9, 2010
  • Returned for modification May 18, 2010
  • Accepted June 2, 2010
  • Published online July 15, 2010.

Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (June 14, 2010).
  • You are viewing the most recent version of this article.

Author Information

  1. Soo-Jin Yang1*,
  2. Yan Q. Xiong1,2,
  3. Susan Boyle-Vavra3,
  4. Robert Daum3,
  5. Tiffanny Jones1 and
  6. Arnold S. Bayer1,2
  1. 1Los Angeles Biomedical Research Institute, Torrance, California
  2. 2David Geffen School of Medicine, UCLA, Los Angeles, California
  3. 3Department of Pediatrics, University of Chicago, Chicago, Illinois
  • ↵* Corresponding author. Mailing address: LA Biomedical Research Institute at Harbor—UCLA, 1124 West Carson Street, RB-2, Rm. 230, Torrance, CA 90502. Phone: (310) 222-6423. Fax: (310) 782-2016. E-mail: sjyang{at}labiomed.org
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Daptomycin-Oxacillin Combinations in Treatment of Experimental Endocarditis Caused by Daptomycin-Nonsusceptible Strains of Methicillin-Resistant Staphylococcus aureus with Evolving Oxacillin Susceptibility (the “Seesaw Effect”)
Soo-Jin Yang, Yan Q. Xiong, Susan Boyle-Vavra, Robert Daum, Tiffanny Jones, Arnold S. Bayer
Antimicrobial Agents and Chemotherapy Jul 2010, 54 (8) 3161-3169; DOI: 10.1128/AAC.00487-10

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Daptomycin-Oxacillin Combinations in Treatment of Experimental Endocarditis Caused by Daptomycin-Nonsusceptible Strains of Methicillin-Resistant Staphylococcus aureus with Evolving Oxacillin Susceptibility (the “Seesaw Effect”)
Soo-Jin Yang, Yan Q. Xiong, Susan Boyle-Vavra, Robert Daum, Tiffanny Jones, Arnold S. Bayer
Antimicrobial Agents and Chemotherapy Jul 2010, 54 (8) 3161-3169; DOI: 10.1128/AAC.00487-10
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KEYWORDS

Anti-Bacterial Agents
daptomycin
Disease Models, Animal
Drug Resistance, Bacterial
Endocarditis, Bacterial
methicillin-resistant Staphylococcus aureus
oxacillin

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