Mechanisms of Resistance

In Vitro Activities of Quinine and Other Antimalarials and pfnhe Polymorphisms in Plasmodium Isolates from Kenya

John Okombo, Steven M. Kiara, Josea Rono, Leah Mwai, Lewa Pole, Eric Ohuma, Steffen Borrmann, Lynette Isabella Ochola, Alexis Nzila
DOI: 10.1128/AAC.00325-10

Article Information

DOI 
https://doi.org/10.1128/AAC.00325-10
PubMed 
20516285
Published By 
American Society for Microbiology Journals
History 
  • Received March 9, 2010
  • Returned for modification April 25, 2010
  • Accepted May 23, 2010
  • Published online July 15, 2010.
Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

Author Information

  1. John Okombo1,
  2. Steven M. Kiara1,
  3. Josea Rono1,
  4. Leah Mwai1,2,
  5. Lewa Pole1,
  6. Eric Ohuma1,
  7. Steffen Borrmann1,3,
  8. Lynette Isabella Ochola1 and
  9. Alexis Nzila1,2*
  1. 1Kenya Medical Research Institute (KEMRI)/Wellcome Trust Collaborative Research Program, P.O. Box 230, 80108 Kilifi, Kenya
  2. 2 University of Oxford, Nuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom
  3. 3Institute of Hygiene, University of Heidelberg School of Medicine, Heidelberg, Germany
  • ↵* Corresponding author. Mailing address: Kenya Medical Research Institute (KEMRI)/Wellcome Trust Collaborative Research Program, P.O. Box 230, 80108 Kilifi, Kenya. Phone: 254-41-522535. Fax: 254-41-522390. E-mail: anzila{at}kilifi.kemri-wellcome.org

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KEYWORDS

antimalarials
Plasmodium falciparum
Polymorphism, Genetic
Quinine
Sodium-Hydrogen Exchangers

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