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Table of Contents

November 1, 2011; Volume 55,Issue 11

Minireview

  • Minireview
    Carbapenems: Past, Present, and Future
    Krisztina M. Papp-Wallace, Andrea Endimiani, Magdalena A. Taracila, Robert A. Bonomo

Experimental Therapeutics

  • Experimental Therapeutics
    Efficacy of Single Intravenous Injection of Peramivir against Influenza B Virus Infection in Ferrets and Cynomolgus Macaques
    Mitsutaka Kitano, Yasushi Itoh, Makoto Kodama, Hirohito Ishigaki, Misako Nakayama, Hideaki Ishida, Kaoru Baba, Takahiro Noda, Kenji Sato, Yoichiro Nihashi, Takushi Kanazu, Ryu Yoshida, Ryuzo Torii, Akihiko Sato, Kazumasa Ogasawara
  • Experimental Therapeutics
    Anidulafungin in Treatment of Experimental Invasive Infection by Candida parapsilosis: In Vitro Activity, (1→3)-β-d-Glucan and Mannan Serum Levels, Histopathological Findings, and In Vivo Efficacy
    Valentina Salas, F. Javier Pastor, Enrique Calvo, Emilio Mayayo, Guillermo Quindós, Alfonso J. Carrillo, Josep Guarro
  • Experimental Therapeutics
    Cethromycin-Mediated Protection against the Plague Pathogen Yersinia pestis in a Rat Model of Infection and Comparison with Levofloxacin
    Jason A. Rosenzweig, Sheri M. Brackman, Michelle L. Kirtley, Jian Sha, Tatiana E. Erova, Linsey A. Yeager, Johnny W. Peterson, Ze-Qi Xu, Ashok K. Chopra
  • Experimental Therapeutics
    Clofazimine Analogs with Efficacy against Experimental Tuberculosis and Reduced Potential for Accumulation
    Yu Lu, Meiqin Zheng, Bin Wang, Lei Fu, Weijie Zhao, Peng Li, Jian Xu, Hui Zhu, Haixia Jin, Dali Yin, Haihong Huang, Anna M. Upton, Zhenkun Ma
  • Experimental Therapeutics
    In Vitro and In Vivo Activities of Novel, Semisynthetic Thiopeptide Inhibitors of Bacterial Elongation Factor Tu
    J. A. Leeds, M. J. LaMarche, J. T. Brewer, S. M. Bushell, G. Deng, J. M. Dewhurst, J. Dzink-Fox, E. Gangl, A. Jain, L. Lee, M. Lilly, K. Manni, S. Mullin, G. Neckermann, C. Osborne, D. Palestrant, M. A. Patane, A. Raimondi, S. Ranjitkar, E. M. Rann, M. Sachdeva, J. Shao, S. Tiamfook, L. Whitehead, D. Yu
  • Experimental Therapeutics
    Impact of Granulocytes on the Antimicrobial Effect of Tedizolid in a Mouse Thigh Infection Model
    G. L. Drusano, Weiguo Liu, Robert Kulawy, Arnold Louie
  • Experimental Therapeutics
    Enhancement of Vancomycin Activity against Biofilms by Using Ultrasound-Targeted Microbubble Destruction
    Nianan He, Jian Hu, Huayong Liu, Tao Zhu, Beijian Huang, Xueqin Wang, Yang Wu, Wenping Wang, Di Qu
  • Experimental Therapeutics
    Characterization of the Retrocyclin Analogue RC-101 as a Preventative of Staphylococcus aureus Nasal Colonization
    Ryan P. Lamers, Colleen R. Eade, Alan J. Waring, Amy L. Cole, Alexander M. Cole

Mechanisms of Resistance

  • Mechanisms of Resistance
    Recombination in IS26 and Tn2 in the Evolution of Multiresistance Regions Carrying blaCTX-M-15 on Conjugative IncF Plasmids from Escherichia coli
    Sally R. Partridge, Zhiyong Zong, Jonathan R. Iredell
  • Mechanisms of Resistance
    Citrobacter spp. as a Source of qnrB Alleles
    George A. Jacoby, Caitlin M. Griffin, David C. Hooper
  • Mechanisms of Resistance
    Bovine Intestinal Bacteria Inactivate and Degrade Ceftiofur and Ceftriaxone with Multiple β-Lactamases
    R. Doug Wagner, Shemedia J. Johnson, Carl E. Cerniglia, Bruce D. Erickson
  • Mechanisms of Resistance
    Interrogation of Related Clinical Pan-Azole-Resistant Aspergillus fumigatus Strains: G138C, Y431C, and G434C Single Nucleotide Polymorphisms in cyp51A, Upregulation of cyp51A, and Integration and Activation of Transposon Atf1 in the cyp51A Promoter
    Ahmed M. Albarrag, Michael J. Anderson, Susan J. Howard, Geoff D. Robson, Peter A. Warn, Dominique Sanglard, David W. Denning
  • Mechanisms of Resistance
    SMB-1, a Novel Subclass B3 Metallo-β-Lactamase, Associated with ISCR1 and a Class 1 Integron, from a Carbapenem-Resistant Serratia marcescens Clinical Isolate
    Jun-ichi Wachino, Hiroyuki Yoshida, Kunikazu Yamane, Satowa Suzuki, Mari Matsui, Takuya Yamagishi, Atsuko Tsutsui, Toshifumi Konda, Keigo Shibayama, Yoshichika Arakawa
  • Mechanisms of Resistance
    Clinical Carbapenem-Resistant Acinetobacter baylyi Strain Coharboring blaSIM-1 and blaOXA-23 from China
    Zhihui Zhou, Xiaoxing Du, Li Wang, Qing Yang, Yiqi Fu, Yunsong Yu
  • Mechanisms of Resistance
    Functional Characterization of Tn4401, a Tn3-Based Transposon Involved in blaKPC Gene Mobilization
    Gaelle Cuzon, Thierry Naas, Patrice Nordmann
  • Mechanisms of Resistance
    Biochemical Characterization of Sfh-I, a Subclass B2 Metallo-β-Lactamase from Serratia fonticola UTAD54
    Fátima Fonseca, Christopher J. Arthur, Elizabeth H. C. Bromley, Bart Samyn, Pablo Moerman, Maria José Saavedra, António Correia, James Spencer
  • Mechanisms of Resistance
    Increased pfmdr1 Copy Number and Sequence Polymorphisms in Plasmodium falciparum Isolates from Sudanese Malaria Patients Treated with Artemether-Lumefantrine
    Nahla B. Gadalla, Ishag Adam, Salah-Eldin Elzaki, Sahar Bashir, Izdihar Mukhtar, Mary Oguike, Amal Gadalla, Fathi Mansour, David Warhurst, Badria B. El-Sayed, Colin J. Sutherland

Pharmacology

  • Pharmacology
    Daptomycin, Fosfomycin, or Both for Treatment of Methicillin-Resistant Staphylococcus aureus Osteomyelitis in an Experimental Rat Model
    W. Poeppl, S. Tobudic, T. Lingscheid, R. Plasenzotti, N. Kozakowski, H. Lagler, A. Georgopoulos, H. Burgmann
  • Pharmacology
    Efficacy of Human-Simulated Exposures of Tomopenem (Formerly CS-023) in a Murine Model of Pseudomonas aeruginosa and Methicillin-Resistant Staphylococcus aureus Infection
    Kiyoshi Sugihara, Kazuhiro Tateda, Naotoshi Yamamura, Tetsufumi Koga, Chika Sugihara, Keizo Yamaguchi
  • Pharmacology
    Comparison of Azithromycin Pharmacokinetics following Single Oral Doses of Extended-Release and Immediate-Release Formulations in Children with Acute Otitis Media
    Ping Liu, Annie F. Fang, Robert R. LaBadie, Penelope H. Crownover, Adriano G. Arguedas
  • Pharmacology
    Meningeal Inflammation Increases Artemether Concentrations in Cerebrospinal Fluid in Papua New Guinean Children Treated with Intramuscular Artemether
    Laurens Manning, Moses Laman, Madhu Page-Sharp, Sam Salman, Ilomo Hwaiwhanje, Namar Morep, Peter Siba, Ivo Mueller, Harin A. Karunajeewa, Timothy M. E. Davis
  • Pharmacology
    Pharmacokinetic Mismatch Does Not Lead to Emergence of Isoniazid- or Rifampin-Resistant Mycobacterium tuberculosis but to Better Antimicrobial Effect: a New Paradigm for Antituberculosis Drug Scheduling
    Shashikant Srivastava, Carleton Sherman, Claudia Meek, Richard Leff, Tawanda Gumbo
  • Pharmacology
    Fractal Geometry and the Pharmacometrics of Micafungin in Overweight, Obese, and Extremely Obese People
    Ronald G. Hall, Mark A. Swancutt, Tawanda Gumbo
  • Pharmacology
    Nelfinavir and Its Active Metabolite, Hydroxy-t-Butylamidenelfinavir (M8), Are Transferred in Small Quantities to Breast Milk and Do Not Reach Biologically Significant Concentrations in Breast-Feeding Infants Whose Mothers Are Taking Nelfinavir
    Paul J. Weidle, Clement Zeh, Amy Martin, Richard Lando, Frank Angira, Joseph Osoga, Paul Ogindo, Sonali Girde, Timothy D. Minniear, Timothy K. Thomas
  • Pharmacology
    Pharmacokinetics of Voriconazole Administered Concomitantly with Fluconazole and Population-Based Simulation for Sequential Use
    Bharat Damle, Manthena V. Varma, Nolan Wood
  • Open Access
    Pharmacology
    Excretion of Moxidectin into Breast Milk and Pharmacokinetics in Healthy Lactating Women
    Joan M. Korth-Bradley, Virginia Parks, Stephan Chalon, Ian Gourley, Kyle Matschke, Sophie Gossart, Philip Bryson, Lawrence Fleckenstein
  • Pharmacology
    Plasma and Tissue Pharmacokinetics of Cefazolin in Patients Undergoing Elective and Semielective Abdominal Aortic Aneurysm Open Repair Surgery
    Alexandra Douglas, Andrew A. Udy, Steven C. Wallis, Paul Jarrett, Janine Stuart, Melissa Lassig-Smith, Renae Deans, Michael S. Roberts, Kersi Taraporewalla, Jason Jenkins, Gregory Medley, Jeffrey Lipman, Jason A. Roberts
  • Pharmacology
    Population Pharmacokinetics of Artemether, Lumefantrine, and Their Respective Metabolites in Papua New Guinean Children with Uncomplicated Malaria
    Sam Salman, Madhu Page-Sharp, Susan Griffin, Kaye Kose, Peter M. Siba, Kenneth F. Ilett, Ivo Mueller, Timothy M. E. Davis
  • Pharmacology
    Population Pharmacokinetic/Pharmacogenetic Model for Optimization of Efavirenz Therapy in Caucasian HIV-Infected Patients
    Almudena Sánchez, Salvador Cabrera, Dolores Santos, M. Paz Valverde, Aurelio Fuertes, Alfonso Domínguez-Gil, María J. García, the Tormes Group
  • Pharmacology
    Efficacy of NZ2114, a Novel Plectasin-Derived Cationic Antimicrobial Peptide Antibiotic, in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus
    Yan Q. Xiong, Wessam Abdel Hady, Antoine Deslandes, Astrid Rey, Laurent Fraisse, Hans-Henrik Kristensen, Michael R. Yeaman, Arnold S. Bayer

Mechanisms of Action: Physiological Effects

  • Mechanisms of Action: Physiological Effects
    Survival of Adhering Staphylococci during Exposure to a Quaternary Ammonium Compound Evaluated by Using Atomic Force Microscopy Imaging
    Mihaela Crismaru, Lia A. T. W. Asri, Ton J. A. Loontjens, Bastiaan P. Krom, Joop de Vries, Henny C. van der Mei, Henk J. Busscher
  • Mechanisms of Action: Physiological Effects
    Antibacterial Mechanism of Action of Arylamide Foldamers
    Bruk Mensa, Yong Ho Kim, Sungwook Choi, Richard Scott, Gregory A. Caputo, William F. DeGrado
  • Mechanisms of Action: Physiological Effects
    A Novel Target-Specific, Salt-Resistant Antimicrobial Peptide against the Cariogenic Pathogen Streptococcus mutans
    Junni Mai, Xiao-Lin Tian, Jeffrey W. Gallant, Nadine Merkley, Zakia Biswas, Raymond Syvitski, Susan E. Douglas, Junqi Ling, Yung-Hua Li
  • Mechanisms of Action: Physiological Effects
    Ctriporin, a New Anti-Methicillin-Resistant Staphylococcus aureus Peptide from the Venom of the Scorpion Chaerilus tricostatus
    Zheng Fan, Luyang Cao, Yawen He, Jun Hu, Zhiyong Di, Yingliang Wu, Wenxin Li, Zhijian Cao
  • Mechanisms of Action: Physiological Effects
    Dynamics of Mutator and Antibiotic-Resistant Populations in a Pharmacokinetic/Pharmacodynamic Model of Pseudomonas aeruginosa Biofilm Treatment
    María D. Macià, José L. Pérez, Soeren Molin, Antonio Oliver
  • Mechanisms of Action: Physiological Effects
    Role of Lipid II and Membrane Thickness in the Mechanism of Action of the Lantibiotic Bovicin HC5
    Aline Dias Paiva, Eefjan Breukink, Hilário Cuquetto Mantovani
  • Open Access
    Mechanisms of Action: Physiological Effects
    Pyrazinoic Acid Decreases the Proton Motive Force, Respiratory ATP Synthesis Activity, and Cellular ATP Levels
    Ping Lu, Anna C. Haagsma, Hoang Pham, Janneke J. Maaskant, Selena Mol, Holger Lill, Dirk Bald
  • Mechanisms of Action: Physiological Effects
    Spider Venom Peptides for Gene Therapy of Chlamydia Infection
    Vassili N. Lazarev, Nadezhda F. Polina, Marina M. Shkarupeta, Elena S. Kostrjukova, Alexander A. Vassilevski, Sergey A. Kozlov, Eugene V. Grishin, Vadim M. Govorun
  • Mechanisms of Action: Physiological Effects
    Selective Killing of Bacterial Persisters by a Single Chemical Compound without Affecting Normal Antibiotic-Sensitive Cells
    Jun-Seob Kim, Paul Heo, Tae-Jun Yang, Ki-Sing Lee, Da-Hyeong Cho, Bum Tae Kim, Ji-Hee Suh, Hee-Jong Lim, Dongwoo Shin, Sung-Koo Kim, Dae-Hyuk Kweon

Clinical Therapeutics

  • Clinical Therapeutics
    Mortality in Hematologic Malignancy and Hematopoietic Stem Cell Transplant Patients with Mucormycosis, 2001 to 2009
    Sarah P. Hammond, Lindsey R. Baden, Francisco M. Marty
  • Clinical Therapeutics
    Is Cefazolin Inferior to Nafcillin for Treatment of Methicillin-Susceptible Staphylococcus aureus Bacteremia?
    Shinwon Lee, Pyoeng Gyun Choe, Kyoung-Ho Song, Sang-Won Park, Hong Bin Kim, Nam Joong Kim, Eui-Chong Kim, Wan Beom Park, Myoung-don Oh
  • Clinical Therapeutics
    Prior Caspofungin Exposure in Patients with Hematological Malignancies Is a Risk Factor for Subsequent Fungemia Due to Decreased Susceptibility in Candida spp.: a Case-Control Study in Paris, France
    Elodie Blanchard, Olivier Lortholary, Karine Boukris-Sitbon, Marie Desnos-Ollivier, Françoise Dromer, Didier Guillemot, the French Mycosis Study Group

Antiviral Agents

  • Antiviral Agents
    Identification of Protein-Protein Interaction Inhibitors Targeting Vaccinia Virus Processivity Factor for Development of Antiviral Agents
    Norbert Schormann, Charnell Inglis Sommers, Mark N. Prichard, Kathy A. Keith, James W. Noah, Manunya Nuth, Robert P. Ricciardi, Debasish Chattopadhyay
  • Antiviral Agents
    Inhibition of HIV-1 by Octadecyloxyethyl Esters of (S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl] Nucleosides and Evaluation of Their Mechanism of Action
    Wendy C. Magee, Nadejda Valiaeva, James R. Beadle, Douglas D. Richman, Karl Y. Hostetler, David H. Evans
  • Antiviral Agents
    Impact of Mutations Outside the V3 Region on Coreceptor Tropism Phenotypically Assessed in Patients Infected with HIV-1 Subtype B
    Laura Monno, Annalisa Saracino, Luigia Scudeller, Grazia Punzi, Gaetano Brindicci, Maurantonio Altamura, Antonella Lagioia, Nicoletta Ladisa, Gioacchino Angarano
  • Antiviral Agents
    Efficient Identification of Human Immunodeficiency Virus Type 1 Mutants Resistant to a Protease Inhibitor by Using a Random Mutant Library
    Sanggu Kim, Yun-Cheol Kim, Hangfei Qi, Kunkai Su, Sherie L. Morrison, Samson A. Chow
  • Antiviral Agents
    MK-0536 Inhibits HIV-1 Integrases Resistant to Raltegravir
    Mathieu Métifiot, Barry Johnson, Steven Smith, Xue Zhi Zhao, Christophe Marchand, Terrence Burke, Stephen Hughes, Yves Pommier
  • Antiviral Agents
    Griffithsin Has Antiviral Activity against Hepatitis C Virus
    Philip Meuleman, Anna Albecka, Sandrine Belouzard, Koen Vercauteren, Lieven Verhoye, Czeslaw Wychowski, Geert Leroux-Roels, Kenneth E. Palmer, Jean Dubuisson
  • Antiviral Agents
    Zanamivir Pharmacokinetics and Pulmonary Penetration into Epithelial Lining Fluid following Intravenous or Oral Inhaled Administration to Healthy Adult Subjects
    Mark J. Shelton, Mark Lovern, Judith Ng-Cashin, Lori Jones, Elizabeth Gould, Jennifer Gauvin, Keith A. Rodvold
  • Antiviral Agents
    Development of Dual-Acting Pyrimidinediones as Novel and Highly Potent Topical Anti-HIV Microbicides
    Karen Watson Buckheit, Lu Yang, Robert W. Buckheit
  • Open Access
    Antiviral Agents
    Phase III Randomized, Double-Blind Study Comparing Single-Dose Intravenous Peramivir with Oral Oseltamivir in Patients with Seasonal Influenza Virus Infection
    Shigeru Kohno, Muh-Yong Yen, Hee-Jin Cheong, Nobuo Hirotsu, Tadashi Ishida, Jun-ichi Kadota, Masashi Mizuguchi, Hiroshi Kida, Jingoro Shimada
    and for the S-021812 Clinical Study Group
  • Antiviral Agents
    Plasma and Intracellular Population Pharmacokinetic Analysis of Tenofovir in HIV-1-Infected Patients
    Gautam Baheti, Jennifer J. Kiser, Peter L. Havens, Courtney V. Fletcher
  • Antiviral Agents
    Comparison of Drug Resistance Scores for Tipranavir in Protease Inhibitor-Naïve Patients Infected with HIV-1 B and Non-B Subtypes
    Martin Stürmer, Christoph Stephan, Peter Gute, Gaby Knecht, Markus Bickel, Hans-Reinhard Brodt, Hans W. Doerr, Lutz Gürtler, Pierre Lecocq, Margriet van Houtte

Susceptibility

  • Susceptibility
    In Vitro Activity of Antiretroviral Drugs against Plasmodium falciparum
    Christian Nsanzabana, Philip J. Rosenthal
  • Susceptibility
    Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors
    Scott S. Walker, Yiming Xu, Ilias Triantafyllou, Michelle F. Waldman, Cara Mendrick, Nathaniel Brown, Paul Mann, Andrew Chau, Reena Patel, Nicholas Bauman, Christine Norris, Barry Antonacci, Maya Gurnani, Anthony Cacciapuoti, Paul M. McNicholas, Samuel Wainhaus, R. Jason Herr, Rongze Kuang, Robert G. Aslanian, Pauline C. Ting, Todd A. Black
  • Susceptibility
    Clinically Relevant Plasma Concentrations of Colistin in Combination with Imipenem Enhance Pharmacodynamic Activity against Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula
    Phillip J. Bergen, Alan Forrest, Jürgen B. Bulitta, Brian T. Tsuji, Hanna E. Sidjabat, David L. Paterson, Jian Li, Roger L. Nation
  • Susceptibility
    In Vitro Activity of a Novel Broad-Spectrum Antifungal, E1210, Tested against Aspergillus spp. Determined by CLSI and EUCAST Broth Microdilution Methods
    Michael A. Pfaller, Frederick Duncanson, Shawn A. Messer, Gary J. Moet, Ronald N. Jones, Mariana Castanheira
  • Susceptibility
    Comparative Susceptibilities to Fidaxomicin (OPT-80) of Isolates Collected at Baseline, Recurrence, and Failure from Patients in Two Phase III Trials of Fidaxomicin against Clostridium difficile Infection
    Ellie J. C. Goldstein, Diane M. Citron, Pamela Sears, Farah Babakhani, Susan P. Sambol, Dale N. Gerding
  • Susceptibility
    Intrinsic Epidemicity of Streptococcus pneumoniae Depends on Strain Serotype and Antibiotic Susceptibility Pattern
    Matthieu Domenech de Cellès, Lulla Opatowski, Jérôme Salomon, Emmanuelle Varon, Claude Carbon, Pierre-Yves Boëlle, Didier Guillemot
  • Susceptibility
    Helicobacter pylori Resistance to Rifabutin in the Last 7 Years
    Toshihiro Nishizawa, Hidekazu Suzuki, Juntaro Matsuzaki, Hiroe Muraoka, Hitoshi Tsugawa, Kenro Hirata, Toshifumi Hibi
  • Susceptibility
    Functional Synergy between Antimicrobial Peptoids and Peptides against Gram-Negative Bacteria
    Nathaniel P. Chongsiriwatana, Modi Wetzler, Annelise E. Barron

Epidemiology and Surveillance

  • Epidemiology and Surveillance
    Wild-Type MIC Distributions and Epidemiological Cutoff Values for Amphotericin B and Aspergillus spp. for the CLSI Broth Microdilution Method (M38-A2 Document)
    A. Espinel-Ingroff, M. Cuenca-Estrella, A. Fothergill, J. Fuller, M. Ghannoum, E. Johnson, T. Pelaez, M. A. Pfaller, J. Turnidge
  • Epidemiology and Surveillance
    ArmA Methyltransferase in a Monophasic Salmonella enterica Isolate from Food
    Sophie A. Granier, Laura Hidalgo, Alvaro San Millan, Jose Antonio Escudero, Belen Gutierrez, Anne Brisabois, Bruno Gonzalez-Zorn
  • Epidemiology and Surveillance
    Wide Dissemination of Pseudomonas aeruginosa Producing β-Lactamase blaKPC-2 Gene in Colombia
    Gaelle Cuzon, Thierry Naas, Maria-Virginia Villegas, Adriana Correa, John P. Quinn, Patrice Nordmann
  • Epidemiology and Surveillance
    Environmental Microbiota Represents a Natural Reservoir for Dissemination of Clinically Relevant Metallo-β-Lactamases
    Claudia Scotta, Carlos Juan, Gabriel Cabot, Antonio Oliver, Jorge Lalucat, Antonio Bennasar, Sebastián Albertí
  • Epidemiology and Surveillance
    Transmission of Dapsone-Resistant Leprosy Detected by Molecular Epidemiological Approaches
    Wei Li, Rama M. Sakamuri, Danielle E. Lyons, Florenda M. Orcullo, Vidyagouri Shinde, Edred Lao Dela Pena, Armi A. Maghanoy, Irene B. Mallari, Esterlina V. Tan, Indira Nath, Patrick J. Brennan, Marivic Balagon, Varalakshmi Vissa
  • Open Access
    Epidemiology and Surveillance
    Survey of Antimicrobial Resistance in Clinical Burkholderia pseudomallei Isolates over Two Decades in Northeast Thailand
    Vanaporn Wuthiekanun, Premjit Amornchai, Natnaree Saiprom, Narisara Chantratita, Wirongrong Chierakul, Gavin C. K. W. Koh, Wipada Chaowagul, Nicholas P. J. Day, Direk Limmathurotsakul, Sharon J. Peacock
  • Epidemiology and Surveillance
    Dissemination of an NDM-2-Producing Acinetobacter baumannii Clone in an Israeli Rehabilitation Center
    P. Espinal, G. Fugazza, Y. López, M. Kasma, Y. Lerman, S. Malhotra-Kumar, H. Goossens, Y. Carmeli, J. Vila
  • Epidemiology and Surveillance
    Genetic Features of blaNDM-1-Positive Enterobacteriaceae
    Laurent Poirel, Laurent Dortet, Sandrine Bernabeu, Patrice Nordmann

Analytical Procedures

  • Analytical Procedures
    Application of Bacterial Bioluminescence To Assess the Efficacy of Fast-Acting Biocides
    Gareth M. Robinson, Katherine M. Tonks, Robin M. S. Thorn, Darren M. Reynolds

Recent U.S. Food and Drug Administration Approvals

  • Free
    Recent U.S. Food and Drug Administration Approvals
    New Antimicrobial Agents Approved by the U.S. Food and Drug Administration in 2010 and 2011 and New Indications for Previously Approved Agentsa

Letter to the Editor

  • Letter to the Editor
    Occurrence of the Carbapenem-Hydrolyzing β-Lactamase Gene blaOXA-48 in the Environment in Morocco
    Anaïs Potron, Laurent Poirel, Florence Bussy, Patrice Nordmann

Erratum

  • Erratum
    Observational Study of the Clinical Efficacy of Voriconazole and Its Relationship to Plasma Concentrations in Patients
    Peter F. Troke, Hans P. Hockey, William W. Hope
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Antimicrobial Agents and Chemotherapy: 55 (11)

In This Issue

volume 55, issue 11
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  • Minireview
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  • Recent U.S. Food and Drug Administration Approvals
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  • Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity Against SARS-CoV-2
  • Mechanism-of-Action Classification of Antibiotics by Global Transcriptome Profiling
  • Fact versus Fiction: a Review of the Evidence behind Alcohol and Antibiotic Interactions
  • Povidone Iodine: Properties, Mechanisms of Action, and Role in Infection Control and Staphylococcus aureus Decolonization
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