Table of Contents
Pharmacology
- PharmacologyOptimization of Aminoglycoside Therapy
Mechanisms of Resistance
- Mechanisms of ResistanceMutations in gidB Confer Low-Level Streptomycin Resistance in Mycobacterium tuberculosis
- Mechanisms of ResistancePME-1, an Extended-Spectrum β-Lactamase Identified in Pseudomonas aeruginosa
- Mechanisms of ResistanceFirst Report of Klebsiella oxytoca Strain Coproducing KPC-2 and IMP-8 Carbapenemases
- Mechanisms of ResistanceEmergence of Escherichia coli Sequence Type ST131 Carrying both the blaGES-5 and blaCTX-M-15 Genes
- Mechanisms of ResistanceA Novel Gene Cassette, aacA43, in a Plasmid-Borne Class 1 Integron
- Mechanisms of ResistanceEmergence of NDM-1-Producing Enterobacteriaceae in Belgium
Experimental Therapeutics
- Experimental TherapeuticsActivity of Carbapenems Combined with Clavulanate against Murine Tuberculosis
- Experimental TherapeuticsAminoindoles, a Novel Scaffold with Potent Activity against Plasmodium falciparum
- Experimental TherapeuticsChemical Characterization and Biological Properties of NVC-422, a Novel, Stable N-Chlorotaurine Analog
- Experimental TherapeuticsSaturability of Granulocyte Kill of Pseudomonas aeruginosa in a Murine Model of Pneumonia
- Experimental TherapeuticsDouble-Carbapenem Therapy for Carbapenemase-Producing Klebsiella pneumoniae
- Experimental TherapeuticsAntimalarial Effects of Human Immunodeficiency Virus Protease Inhibitors in Rhesus Macaques
- Experimental TherapeuticsAntimicrobial Peptoids Are Effective against Pseudomonas aeruginosa Biofilms
Mechanisms of Action: Physiological Effects
- Mechanisms of Action: Physiological EffectsProteomic Signature of Fatty Acid Biosynthesis Inhibition Available for In Vivo Mechanism-of-Action Studies
- Mechanisms of Action: Physiological EffectsDynamics of the Action of Biocides in Pseudomonas aeruginosa Biofilms
- Mechanisms of Action: Physiological EffectsQuorum Sensing Inhibitors Increase the Susceptibility of Bacterial Biofilms to Antibiotics In Vitro and In Vivo
- Mechanisms of Action: Physiological EffectsNovel Inhibitors of the Pseudomonas aeruginosa Virulence Factor LasB: a Potential Therapeutic Approach for the Attenuation of Virulence Mechanisms in Pseudomonal Infection
- Mechanisms of Action: Physiological EffectsA New Small Molecule Specifically Inhibits the Cariogenic Bacterium Streptococcus mutans in Multispecies Biofilms
- Mechanisms of Action: Physiological EffectsDecrease in Penicillin Susceptibility Due to Heat Shock Protein ClpL in Streptococcus pneumoniae
- Mechanisms of Action: Physiological EffectsMechanism of Action and Limited Cross-Resistance of New Lipopeptide MX-2401
- Mechanisms of Action: Physiological EffectsUse of a Selective Inhibitor To Define the Chemotherapeutic Potential of the Plasmodial Hexose Transporter in Different Stages of the Parasite's Life Cycle
- Mechanisms of Action: Physiological EffectsIn Vitro and In Vivo Profiles of ACH-702, an Isothiazoloquinolone, against Bacterial Pathogens
- Mechanisms of Action: Physiological EffectsStructure-Activity Studies and Therapeutic Potential of Host Defense Peptides of Human Thrombin
- Mechanisms of Action: Physiological EffectsCholesterol Enhances Helicobacter pylori Resistance to Antibiotics and LL-37
Epidemiology and Surveillance
- Epidemiology and SurveillanceConsumption Patterns and In Vitro Resistance of Streptococcus pneumoniae to Fluoroquinolones
Clinical Therapeutics
- Clinical TherapeuticsEnhancement of Amoxicillin Resistance after Unsuccessful Helicobacter pylori Eradication