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Mechanisms of Resistance

High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure

Magnus Unemo, Daniel Golparian, Robert Nicholas, Makoto Ohnishi, Anne Gallay, Patrice Sednaoui
Magnus Unemo
WHO Collaborating Centre for Gonorrhoea and Other STIs, Department of Laboratory Medicine, Microbiology, Örebro University Hospital, Örebro, Sweden
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Daniel Golparian
WHO Collaborating Centre for Gonorrhoea and Other STIs, Department of Laboratory Medicine, Microbiology, Örebro University Hospital, Örebro, Sweden
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Robert Nicholas
Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina, USA
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Makoto Ohnishi
National Institute of Infectious Diseases, Tokyo, Japan
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Anne Gallay
Institut de Veille Sanitaire, Saint-Maurice, France
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Patrice Sednaoui
Institut Alfred Fournier, Centre National de Référence des Gonocoques, Paris, France
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DOI: 10.1128/AAC.05760-11
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Article Information

DOI 
https://doi.org/10.1128/AAC.05760-11
PubMed 
22155830

Published By 
American Society for Microbiology Journals
History 
  • Received September 20, 2011
  • Returned for modification November 7, 2011
  • Accepted December 6, 2011
  • Published online February 14, 2012.

Copyright & Usage 
Copyright © 2012, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (December 12, 2011).
  • You are viewing the most recent version of this article.

Author Information

  1. Magnus Unemoa,
  2. Daniel Golpariana,
  3. Robert Nicholasb,
  4. Makoto Ohnishic,
  5. Anne Gallayd and
  6. Patrice Sednaouie
  1. aWHO Collaborating Centre for Gonorrhoea and Other STIs, Department of Laboratory Medicine, Microbiology, Örebro University Hospital, Örebro, Sweden
  2. bDepartment of Pharmacology, University of North Carolina, Chapel Hill, North Carolina, USA
  3. cNational Institute of Infectious Diseases, Tokyo, Japan
  4. dInstitut de Veille Sanitaire, Saint-Maurice, France
  5. eInstitut Alfred Fournier, Centre National de Référence des Gonocoques, Paris, France
  • Address correspondence to Magnus Unemo, magnus.unemo{at}orebroll.se.
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High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure
Magnus Unemo, Daniel Golparian, Robert Nicholas, Makoto Ohnishi, Anne Gallay, Patrice Sednaoui
Antimicrobial Agents and Chemotherapy Feb 2012, 56 (3) 1273-1280; DOI: 10.1128/AAC.05760-11

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High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure
Magnus Unemo, Daniel Golparian, Robert Nicholas, Makoto Ohnishi, Anne Gallay, Patrice Sednaoui
Antimicrobial Agents and Chemotherapy Feb 2012, 56 (3) 1273-1280; DOI: 10.1128/AAC.05760-11
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