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Pharmacology

Coordinated Roles of Pregnane X Receptor and Constitutive Androstane Receptor in Autoinduction of Voriconazole Metabolism in Mice

Masato Ohbuchi, Kouichi Yoshinari, Hayato Kaneko, Satoru Matsumoto, Akiko Inoue, Akio Kawamura, Takashi Usui, Yasushi Yamazoe
Masato Ohbuchi
aDivision of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Science, Tohoku University, Miyagi, Japan
bDrug Metabolism Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Osaka, Japan
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Kouichi Yoshinari
aDivision of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Science, Tohoku University, Miyagi, Japan
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Hayato Kaneko
bDrug Metabolism Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Osaka, Japan
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Satoru Matsumoto
cApplied Pharmacology Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan
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Akiko Inoue
bDrug Metabolism Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Osaka, Japan
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Akio Kawamura
bDrug Metabolism Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Osaka, Japan
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Takashi Usui
bDrug Metabolism Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Osaka, Japan
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Yasushi Yamazoe
aDivision of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Science, Tohoku University, Miyagi, Japan
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DOI: 10.1128/AAC.01900-12
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Article Information

DOI 
https://doi.org/10.1128/AAC.01900-12
PubMed 
23274663

Published By 
American Society for Microbiology Journals
History 
  • Received September 24, 2012
  • Accepted December 21, 2012
  • Published online February 14, 2013.

Copyright & Usage 
Copyright © 2013, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (December 28, 2012).
  • You are viewing the most recent version of this article.

Author Information

  1. Masato Ohbuchia,b,
  2. Kouichi Yoshinaria,
  3. Hayato Kanekob,
  4. Satoru Matsumotoc,
  5. Akiko Inoueb,
  6. Akio Kawamurab,
  7. Takashi Usuib and
  8. Yasushi Yamazoea
  1. aDivision of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Science, Tohoku University, Miyagi, Japan
  2. bDrug Metabolism Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Osaka, Japan
  3. cApplied Pharmacology Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan
  • Address correspondence to Masato Ohbuchi, masato.ohbuchi{at}astellas.com.
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Coordinated Roles of Pregnane X Receptor and Constitutive Androstane Receptor in Autoinduction of Voriconazole Metabolism in Mice
Masato Ohbuchi, Kouichi Yoshinari, Hayato Kaneko, Satoru Matsumoto, Akiko Inoue, Akio Kawamura, Takashi Usui, Yasushi Yamazoe
Antimicrobial Agents and Chemotherapy Feb 2013, 57 (3) 1332-1338; DOI: 10.1128/AAC.01900-12

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Coordinated Roles of Pregnane X Receptor and Constitutive Androstane Receptor in Autoinduction of Voriconazole Metabolism in Mice
Masato Ohbuchi, Kouichi Yoshinari, Hayato Kaneko, Satoru Matsumoto, Akiko Inoue, Akio Kawamura, Takashi Usui, Yasushi Yamazoe
Antimicrobial Agents and Chemotherapy Feb 2013, 57 (3) 1332-1338; DOI: 10.1128/AAC.01900-12
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