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Experimental Therapeutics

Low or High Doses of Cefquinome Targeting Low or High Bacterial Inocula Cure Klebsiella pneumoniae Lung Infections but Differentially Impact the Levels of Antibiotic Resistance in Fecal Flora

Maleck V. Vasseur, Michel Laurentie, Jean-Guy Rolland, Agnès Perrin-Guyomard, Jérôme Henri, Aude A. Ferran, Pierre-Louis Toutain, Alain Bousquet-Mélou
Maleck V. Vasseur
aINRA, UMR1331 TOXALIM, Toulouse, France
bUniversité de Toulouse, INPT, ENVT, EIP, UPS, Toulouse, France
cAnses, Laboratoire de Fougères, Fougères, France
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Michel Laurentie
cAnses, Laboratoire de Fougères, Fougères, France
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Jean-Guy Rolland
cAnses, Laboratoire de Fougères, Fougères, France
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Agnès Perrin-Guyomard
cAnses, Laboratoire de Fougères, Fougères, France
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Jérôme Henri
cAnses, Laboratoire de Fougères, Fougères, France
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Aude A. Ferran
aINRA, UMR1331 TOXALIM, Toulouse, France
bUniversité de Toulouse, INPT, ENVT, EIP, UPS, Toulouse, France
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Pierre-Louis Toutain
aINRA, UMR1331 TOXALIM, Toulouse, France
bUniversité de Toulouse, INPT, ENVT, EIP, UPS, Toulouse, France
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Alain Bousquet-Mélou
aINRA, UMR1331 TOXALIM, Toulouse, France
bUniversité de Toulouse, INPT, ENVT, EIP, UPS, Toulouse, France
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DOI: 10.1128/AAC.02135-13
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Article Information

DOI 
https://doi.org/10.1128/AAC.02135-13
PubMed 
24395228

Published By 
American Society for Microbiology Journals
History 
  • Received October 8, 2013
  • Returned for modification November 17, 2013
  • Accepted December 29, 2013
  • Published online February 19, 2014.

Copyright & Usage 
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (January 06, 2014).
  • You are viewing the most recent version of this article.

Author Information

  1. Maleck V. Vasseura,b,c,
  2. Michel Laurentiec,
  3. Jean-Guy Rollandc,
  4. Agnès Perrin-Guyomardc,
  5. Jérôme Henric,
  6. Aude A. Ferrana,b,
  7. Pierre-Louis Toutaina,b and
  8. Alain Bousquet-Méloua,b
  1. aINRA, UMR1331 TOXALIM, Toulouse, France
  2. bUniversité de Toulouse, INPT, ENVT, EIP, UPS, Toulouse, France
  3. cAnses, Laboratoire de Fougères, Fougères, France
  • Address correspondence to Alain Bousquet-Mélou, a.bousquet-melou{at}envt.fr.
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Low or High Doses of Cefquinome Targeting Low or High Bacterial Inocula Cure Klebsiella pneumoniae Lung Infections but Differentially Impact the Levels of Antibiotic Resistance in Fecal Flora
Maleck V. Vasseur, Michel Laurentie, Jean-Guy Rolland, Agnès Perrin-Guyomard, Jérôme Henri, Aude A. Ferran, Pierre-Louis Toutain, Alain Bousquet-Mélou
Antimicrobial Agents and Chemotherapy Feb 2014, 58 (3) 1744-1748; DOI: 10.1128/AAC.02135-13

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Low or High Doses of Cefquinome Targeting Low or High Bacterial Inocula Cure Klebsiella pneumoniae Lung Infections but Differentially Impact the Levels of Antibiotic Resistance in Fecal Flora
Maleck V. Vasseur, Michel Laurentie, Jean-Guy Rolland, Agnès Perrin-Guyomard, Jérôme Henri, Aude A. Ferran, Pierre-Louis Toutain, Alain Bousquet-Mélou
Antimicrobial Agents and Chemotherapy Feb 2014, 58 (3) 1744-1748; DOI: 10.1128/AAC.02135-13
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