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Antiviral Agents

Ruxolitinib and Tofacitinib Are Potent and Selective Inhibitors of HIV-1 Replication and Virus Reactivation In Vitro

Christina Gavegnano, Mervi Detorio, Catherine Montero, Alberto Bosque, Vicente Planelles, Raymond F. Schinazi
Christina Gavegnano
aCenter for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
bVeterans Affairs Medical Center, Decatur, Georgia, USA
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Mervi Detorio
aCenter for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
bVeterans Affairs Medical Center, Decatur, Georgia, USA
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Catherine Montero
aCenter for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
bVeterans Affairs Medical Center, Decatur, Georgia, USA
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Alberto Bosque
cDepartment of Pathology, University of Utah, Salt Lake City, Utah, USA
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Vicente Planelles
cDepartment of Pathology, University of Utah, Salt Lake City, Utah, USA
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Raymond F. Schinazi
aCenter for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
bVeterans Affairs Medical Center, Decatur, Georgia, USA
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DOI: 10.1128/AAC.02496-13
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Article Information

DOI 
https://doi.org/10.1128/AAC.02496-13
PubMed 
24419350

Published By 
American Society for Microbiology Journals
History 
  • Received November 14, 2013
  • Returned for modification December 3, 2013
  • Accepted January 8, 2014
  • Published online March 18, 2014.

Copyright & Usage 
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (January 13, 2014).
  • You are viewing the most recent version of this article.

Author Information

  1. Christina Gavegnanoa,b,
  2. Mervi Detorioa,b,
  3. Catherine Monteroa,b,
  4. Alberto Bosquec,
  5. Vicente Planellesc and
  6. Raymond F. Schinazia,b
  1. aCenter for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
  2. bVeterans Affairs Medical Center, Decatur, Georgia, USA
  3. cDepartment of Pathology, University of Utah, Salt Lake City, Utah, USA
  • Address correspondence to Raymond F. Schinazi, rschina{at}emory.edu.

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Ruxolitinib and Tofacitinib Are Potent and Selective Inhibitors of HIV-1 Replication and Virus Reactivation In Vitro
Christina Gavegnano, Mervi Detorio, Catherine Montero, Alberto Bosque, Vicente Planelles, Raymond F. Schinazi
Antimicrobial Agents and Chemotherapy Mar 2014, 58 (4) 1977-1986; DOI: 10.1128/AAC.02496-13

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Ruxolitinib and Tofacitinib Are Potent and Selective Inhibitors of HIV-1 Replication and Virus Reactivation In Vitro
Christina Gavegnano, Mervi Detorio, Catherine Montero, Alberto Bosque, Vicente Planelles, Raymond F. Schinazi
Antimicrobial Agents and Chemotherapy Mar 2014, 58 (4) 1977-1986; DOI: 10.1128/AAC.02496-13
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