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Experimental Therapeutics

A Novel Anti-PcrV Antibody Providing Enhanced Protection against Pseudomonas aeruginosa in Multiple Animal Infection Models

Paul Warrener, Reena Varkey, Jessica C. Bonnell, Antonio DiGiandomenico, Maria Camara, Kimberly Cook, Li Peng, Jingying Zha, Partha Chowdury, Bret Sellman, C. Kendall Stover
Paul Warrener
aDepartment of Infectious Diseases, MedImmune, LLC, Gaithersburg, Maryland, USA
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Reena Varkey
bAntibody Discovery and Protein Engineering, MedImmune, LLC, Gaithersburg, Maryland, USA
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Jessica C. Bonnell
aDepartment of Infectious Diseases, MedImmune, LLC, Gaithersburg, Maryland, USA
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Antonio DiGiandomenico
aDepartment of Infectious Diseases, MedImmune, LLC, Gaithersburg, Maryland, USA
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Maria Camara
aDepartment of Infectious Diseases, MedImmune, LLC, Gaithersburg, Maryland, USA
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Kimberly Cook
bAntibody Discovery and Protein Engineering, MedImmune, LLC, Gaithersburg, Maryland, USA
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Li Peng
bAntibody Discovery and Protein Engineering, MedImmune, LLC, Gaithersburg, Maryland, USA
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Jingying Zha
aDepartment of Infectious Diseases, MedImmune, LLC, Gaithersburg, Maryland, USA
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Partha Chowdury
bAntibody Discovery and Protein Engineering, MedImmune, LLC, Gaithersburg, Maryland, USA
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Bret Sellman
aDepartment of Infectious Diseases, MedImmune, LLC, Gaithersburg, Maryland, USA
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C. Kendall Stover
aDepartment of Infectious Diseases, MedImmune, LLC, Gaithersburg, Maryland, USA
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DOI: 10.1128/AAC.02643-14
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Article Information

DOI 
https://doi.org/10.1128/AAC.02643-14
PubMed 
24841258

Published By 
American Society for Microbiology Journals
History 
  • Received February 24, 2014
  • Returned for modification April 8, 2014
  • Accepted May 12, 2014
  • Published online July 15, 2014.

Copyright & Usage 
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (May 19, 2014).
  • You are viewing the most recent version of this article.

Author Information

  1. Paul Warrenera,
  2. Reena Varkeyb,
  3. Jessica C. Bonnella,
  4. Antonio DiGiandomenicoa,
  5. Maria Camaraa,
  6. Kimberly Cookb,
  7. Li Pengb,
  8. Jingying Zhaa,
  9. Partha Chowduryb,
  10. Bret Sellmana and
  11. C. Kendall Stovera
  1. aDepartment of Infectious Diseases, MedImmune, LLC, Gaithersburg, Maryland, USA
  2. bAntibody Discovery and Protein Engineering, MedImmune, LLC, Gaithersburg, Maryland, USA
  • Address correspondence to C. Kendall Stover, stoverk{at}medimmune.com.
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A Novel Anti-PcrV Antibody Providing Enhanced Protection against Pseudomonas aeruginosa in Multiple Animal Infection Models
Paul Warrener, Reena Varkey, Jessica C. Bonnell, Antonio DiGiandomenico, Maria Camara, Kimberly Cook, Li Peng, Jingying Zha, Partha Chowdury, Bret Sellman, C. Kendall Stover
Antimicrobial Agents and Chemotherapy Jul 2014, 58 (8) 4384-4391; DOI: 10.1128/AAC.02643-14

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A Novel Anti-PcrV Antibody Providing Enhanced Protection against Pseudomonas aeruginosa in Multiple Animal Infection Models
Paul Warrener, Reena Varkey, Jessica C. Bonnell, Antonio DiGiandomenico, Maria Camara, Kimberly Cook, Li Peng, Jingying Zha, Partha Chowdury, Bret Sellman, C. Kendall Stover
Antimicrobial Agents and Chemotherapy Jul 2014, 58 (8) 4384-4391; DOI: 10.1128/AAC.02643-14
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