DOI: 10.1128/AAC.01394-15
ABSTRACT
A novel nonconjugative plasmid of 28,489 bp from a porcine linezolid-resistant Enterococcus faecium isolate was completely sequenced. This plasmid harbored a novel type of multiresistance gene cluster that comprised the resistance genes lnu(B), lsa(E), spw, aadE, aphA3, and two copies of erm(B), which account for resistance to macrolides, lincosamides, streptogramins, pleuromutilins, streptomycin, spectinomycin, and kanamycin/neomycin. Structural comparisons suggested that this plasmid might have developed from other enterococcal plasmids by insertion element (IS)-mediated interplasmid recombination processes.
FOOTNOTES
- Received 13 June 2015.
- Returned for modification 17 July 2015.
- Accepted 20 August 2015.
- Accepted manuscript posted online 31 August 2015.
Supplemental material for this article may be found at http://dx.doi.org/10.1128/AAC.01394-15.
- Copyright © 2015, American Society for Microbiology. All Rights Reserved.
