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Clinical Therapeutics

Open-Label, Single-Dose, Parallel-Group Study in Healthy Volunteers To Determine the Drug-Drug Interaction Potential between KAE609 (Cipargamin) and Piperaquine

Daniel S. Stein, Jay Prakash Jain, Michael Kangas, Gilbert Lefèvre, Surendra Machineni, Paul Griffin, Jason Lickliter
Daniel S. Stein
aNovartis Institute for BioMedical Research, East Hanover, New Jersey, USA
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Jay Prakash Jain
bNovartis Institute for BioMedical Research, Hyberabad, India
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Michael Kangas
cNovartis Institute for BioMedical Research, Basel, Switzerland
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Gilbert Lefèvre
cNovartis Institute for BioMedical Research, Basel, Switzerland
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Surendra Machineni
dIntegrated Quantitative Sciences, Hyderabad, India
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Paul Griffin
eQ-Pharm Pty. Ltd., QIMR Berghofer Medical Research Institute, Mater Health Services and Mater Research, and the University of Queensland, Brisbane, Queensland, Australia
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Jason Lickliter
fNucleus Network Ltd., Melbourne, Victoria, Australia
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DOI: 10.1128/AAC.00340-15
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Article Information

DOI 
https://doi.org/10.1128/AAC.00340-15
PubMed 
25845867

Published By 
American Society for Microbiology Journals
History 
  • Received February 10, 2015
  • Returned for modification March 20, 2015
  • Accepted March 29, 2015
  • Published online May 14, 2015.

Copyright & Usage 
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (April 06, 2015).
  • You are viewing the most recent version of this article.

Author Information

  1. Daniel S. Steina,
  2. Jay Prakash Jainb,
  3. Michael Kangasc,
  4. Gilbert Lefèvrec,
  5. Surendra Machinenid,
  6. Paul Griffine and
  7. Jason Lickliterf
  1. aNovartis Institute for BioMedical Research, East Hanover, New Jersey, USA
  2. bNovartis Institute for BioMedical Research, Hyberabad, India
  3. cNovartis Institute for BioMedical Research, Basel, Switzerland
  4. dIntegrated Quantitative Sciences, Hyderabad, India
  5. eQ-Pharm Pty. Ltd., QIMR Berghofer Medical Research Institute, Mater Health Services and Mater Research, and the University of Queensland, Brisbane, Queensland, Australia
  6. fNucleus Network Ltd., Melbourne, Victoria, Australia
  • Address correspondence to Daniel S. Stein, daniel.stein{at}novartis.com.
  • Citation Stein DS, Jain JP, Kangas M, Lefèvre G, Machineni S, Griffin P, Lickliter J. 2015. Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609 (cipargamin) and piperaquine. Antimicrob Agents Chemother 59:3493–3500. doi:10.1128/AAC.00340-15.

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Open-Label, Single-Dose, Parallel-Group Study in Healthy Volunteers To Determine the Drug-Drug Interaction Potential between KAE609 (Cipargamin) and Piperaquine
Daniel S. Stein, Jay Prakash Jain, Michael Kangas, Gilbert Lefèvre, Surendra Machineni, Paul Griffin, Jason Lickliter
Antimicrobial Agents and Chemotherapy May 2015, 59 (6) 3493-3500; DOI: 10.1128/AAC.00340-15

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Open-Label, Single-Dose, Parallel-Group Study in Healthy Volunteers To Determine the Drug-Drug Interaction Potential between KAE609 (Cipargamin) and Piperaquine
Daniel S. Stein, Jay Prakash Jain, Michael Kangas, Gilbert Lefèvre, Surendra Machineni, Paul Griffin, Jason Lickliter
Antimicrobial Agents and Chemotherapy May 2015, 59 (6) 3493-3500; DOI: 10.1128/AAC.00340-15
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