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Clinical Therapeutics

Pharmacokinetic and Pharmacodynamic Evaluation of a Weight-Based Dosing Regimen of Cefoxitin for Perioperative Surgical Prophylaxis in Obese and Morbidly Obese Patients

Pierre Moine, Scott W. Mueller, Jonathan A. Schoen, Kevin B. Rothchild, Douglas N. Fish
Pierre Moine
aUniversity of Colorado Denver, School of Medicine, Department of Anesthesiology, Aurora, Colorado, USA
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Scott W. Mueller
bDepartment of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA
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Jonathan A. Schoen
cUniversity of Colorado Denver, School of Medicine, Department of Surgery, Surgical Weight Loss Center, Aurora, Colorado, USA
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Kevin B. Rothchild
cUniversity of Colorado Denver, School of Medicine, Department of Surgery, Surgical Weight Loss Center, Aurora, Colorado, USA
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Douglas N. Fish
bDepartment of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA
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DOI: 10.1128/AAC.00585-16
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Article Information

DOI 
https://doi.org/10.1128/AAC.00585-16
PubMed 
27458209

Published By 
American Society for Microbiology Journals
History 
  • Received March 14, 2016
  • Returned for modification April 24, 2016
  • Accepted June 22, 2016
  • Published online September 23, 2016.

Copyright & Usage 
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (July 25, 2016).
  • You are viewing the most recent version of this article.

Author Information

  1. Pierre Moinea,
  2. Scott W. Muellerb,
  3. Jonathan A. Schoenc,
  4. Kevin B. Rothchildc and
  5. Douglas N. Fishb
  1. aUniversity of Colorado Denver, School of Medicine, Department of Anesthesiology, Aurora, Colorado, USA
  2. bDepartment of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA
  3. cUniversity of Colorado Denver, School of Medicine, Department of Surgery, Surgical Weight Loss Center, Aurora, Colorado, USA
  • Address correspondence to Pierre Moine, pierre.moine{at}ucdenver.edu.
  • P.M., S.W.M., and D.N.F. contributed equally to this article.

  • Citation Moine P, Mueller SW, Schoen JA, Rothchild KB, Fish DN. 2016. Pharmacokinetic and pharmacodynamic evaluation of a weight-based dosing regimen of cefoxitin for perioperative surgical prophylaxis in obese and morbidly obese patients. Antimicrob Agents Chemother 60:5885–5893. doi:10.1128/AAC.00585-16.

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Pharmacokinetic and Pharmacodynamic Evaluation of a Weight-Based Dosing Regimen of Cefoxitin for Perioperative Surgical Prophylaxis in Obese and Morbidly Obese Patients
Pierre Moine, Scott W. Mueller, Jonathan A. Schoen, Kevin B. Rothchild, Douglas N. Fish
Antimicrobial Agents and Chemotherapy Sep 2016, 60 (10) 5885-5893; DOI: 10.1128/AAC.00585-16

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Pharmacokinetic and Pharmacodynamic Evaluation of a Weight-Based Dosing Regimen of Cefoxitin for Perioperative Surgical Prophylaxis in Obese and Morbidly Obese Patients
Pierre Moine, Scott W. Mueller, Jonathan A. Schoen, Kevin B. Rothchild, Douglas N. Fish
Antimicrobial Agents and Chemotherapy Sep 2016, 60 (10) 5885-5893; DOI: 10.1128/AAC.00585-16
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