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Clinical Therapeutics

Pharmacokinetic Properties of Micafungin in Critically Ill Patients Diagnosed with Invasive Candidiasis

J. M. Boonstra, K. C. van der Elst, A. Veringa, E. M. Jongedijk, R. J. Brüggemann, R. A. Koster, G. A. Kampinga, J. G. Kosterink, T. S. van der Werf, J. G. Zijlstra, D. J. Touw, J. W. C. Alffenaar
J. M. Boonstra
aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
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K. C. van der Elst
aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
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A. Veringa
aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
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E. M. Jongedijk
aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
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R. J. Brüggemann
bUniversity of Nijmegen, Radboud University Medical Center, Department of Pharmacy, and Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, the Netherlands
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  • ORCID record for R. J. Brüggemann
R. A. Koster
aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
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G. A. Kampinga
cUniversity of Groningen, University Medical Center Groningen, Department of Medical Microbiology and Infection Prevention, Groningen, the Netherlands
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J. G. Kosterink
aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
dUniversity of Groningen, Groningen Research Institute of Pharmacy, Pharmaco-Therapy, Epidemiology, and Economics, Groningen, the Netherlands
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T. S. van der Werf
eUniversity of Groningen, University Medical Center Groningen, Department of Internal Medicine, Groningen, the Netherlands
fUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases and Tuberculosis, Groningen, the Netherlands
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J. G. Zijlstra
gUniversity of Groningen, University Medical Center Groningen, Department of Critical Care, Groningen, the Netherlands
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D. J. Touw
aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
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J. W. C. Alffenaar
aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
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DOI: 10.1128/AAC.01398-17
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Article Information

DOI 
https://doi.org/10.1128/AAC.01398-17
PubMed 
28971861

Published By 
American Society for Microbiology Journals
History 
  • Received July 10, 2017
  • Returned for modification August 5, 2017
  • Accepted September 21, 2017
  • Published online November 22, 2017.

Copyright & Usage 
Copyright © 2017 American Society for Microbiology. All Rights Reserved .

Article Versions

  • Accepted Manuscript version (October 02, 2017).
  • You are viewing the most recent version of this article.

Author Information

  1. J. M. Boonstraa,
  2. K. C. van der Elsta,
  3. A. Veringaa,
  4. E. M. Jongedijka,
  5. R. J. Brüggemannb,
  6. R. A. Kostera,
  7. G. A. Kampingac,
  8. J. G. Kosterinka,d,
  9. T. S. van der Werfe,f,
  10. J. G. Zijlstrag,
  11. D. J. Touwa and
  12. J. W. C. Alffenaara
  1. aUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands
  2. bUniversity of Nijmegen, Radboud University Medical Center, Department of Pharmacy, and Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, the Netherlands
  3. cUniversity of Groningen, University Medical Center Groningen, Department of Medical Microbiology and Infection Prevention, Groningen, the Netherlands
  4. dUniversity of Groningen, Groningen Research Institute of Pharmacy, Pharmaco-Therapy, Epidemiology, and Economics, Groningen, the Netherlands
  5. eUniversity of Groningen, University Medical Center Groningen, Department of Internal Medicine, Groningen, the Netherlands
  6. fUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases and Tuberculosis, Groningen, the Netherlands
  7. gUniversity of Groningen, University Medical Center Groningen, Department of Critical Care, Groningen, the Netherlands
  • Address correspondence to J. W. C. Alffenaar, j.w.c.alffenaar{at}umcg.nl.
  • Citation Boonstra JM, van der Elst KC, Veringa A, Jongedijk EM, Brüggemann RJ, Koster RA, Kampinga GA, Kosterink JG, van der Werf TS, Zijlstra JG, Touw DJ, Alffenaar JWC. 2017. Pharmacokinetic properties of micafungin in critically ill patients diagnosed with invasive candidiasis. Antimicrob Agents Chemother 61:e01398-17. https://doi.org/10.1128/AAC.01398-17 .

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Pharmacokinetic Properties of Micafungin in Critically Ill Patients Diagnosed with Invasive Candidiasis
J. M. Boonstra, K. C. van der Elst, A. Veringa, E. M. Jongedijk, R. J. Brüggemann, R. A. Koster, G. A. Kampinga, J. G. Kosterink, T. S. van der Werf, J. G. Zijlstra, D. J. Touw, J. W. C. Alffenaar
Antimicrobial Agents and Chemotherapy Nov 2017, 61 (12) e01398-17; DOI: 10.1128/AAC.01398-17

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Pharmacokinetic Properties of Micafungin in Critically Ill Patients Diagnosed with Invasive Candidiasis
J. M. Boonstra, K. C. van der Elst, A. Veringa, E. M. Jongedijk, R. J. Brüggemann, R. A. Koster, G. A. Kampinga, J. G. Kosterink, T. S. van der Werf, J. G. Zijlstra, D. J. Touw, J. W. C. Alffenaar
Antimicrobial Agents and Chemotherapy Nov 2017, 61 (12) e01398-17; DOI: 10.1128/AAC.01398-17
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KEYWORDS

antifungal agents
Candida albicans
Candida glabrata
Candidiasis, Invasive
echinocandins
lipopeptides
micafungin
pharmacokinetics
invasive candidiasis
critically ill

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