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Clinical Therapeutics

Clinical Benefit of Appropriate Empirical Fluoroquinolone Therapy for Adults with Community-Onset Bacteremia in Comparison with Third-Generation-Cephalosporin Therapy

Ching-Chi Lee, Jiun-Ling Wang, Chung-Hsun Lee, Chih-Chia Hsieh, Yuan-Pin Hung, Ming-Yuan Hong, Hung-Jen Tang, Wen-Chien Ko
Ching-Chi Lee
aDivision of Critical Care Medicine, Department of Internal Medicine, Madou Sin-Lau Hospital, Tainan, Taiwan
bGraduate Institute of Medical Sciences, College of Health Sciences, Chang Jung Christian University, Tainan, Taiwan
cDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
dDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Jiun-Ling Wang
cDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
dDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Chung-Hsun Lee
dDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Chih-Chia Hsieh
eDepartment of Emergency Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Yuan-Pin Hung
cDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
dDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
fDepartment of Internal Medicine, Tainan Hospital, Ministry of Health and Welfare, Tainan, Taiwan
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Ming-Yuan Hong
dDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
eDepartment of Emergency Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Hung-Jen Tang
gDepartment of Medicine, Chi-Mei Medical Center, Tainan, Taiwan
hDepartment of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan
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Wen-Chien Ko
cDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
dDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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DOI: 10.1128/AAC.02174-16
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Article Information

DOI 
https://doi.org/10.1128/AAC.02174-16
PubMed 
27855072

Published By 
American Society for Microbiology Journals
History 
  • Received October 10, 2016
  • Returned for modification October 22, 2016
  • Accepted October 31, 2016
  • Published online January 24, 2017.

Copyright & Usage 
Copyright © 2017 American Society for Microbiology. All Rights Reserved .

Article Versions

  • Accepted Manuscript version (November 14, 2016).
  • You are viewing the most recent version of this article.

Author Information

  1. Ching-Chi Leea,b,c,d,
  2. Jiun-Ling Wangc,d,
  3. Chung-Hsun Leed,
  4. Chih-Chia Hsiehe,
  5. Yuan-Pin Hungc,d,f,
  6. Ming-Yuan Hongd,e,
  7. Hung-Jen Tangg,h and
  8. Wen-Chien Koc,d
  1. aDivision of Critical Care Medicine, Department of Internal Medicine, Madou Sin-Lau Hospital, Tainan, Taiwan
  2. bGraduate Institute of Medical Sciences, College of Health Sciences, Chang Jung Christian University, Tainan, Taiwan
  3. cDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  4. dDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  5. eDepartment of Emergency Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  6. fDepartment of Internal Medicine, Tainan Hospital, Ministry of Health and Welfare, Tainan, Taiwan
  7. gDepartment of Medicine, Chi-Mei Medical Center, Tainan, Taiwan
  8. hDepartment of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan
  • Address correspondence to Hung-Jen Tang, 8409d1{at}gmail.com, or Wen-Chien Ko, winston3415{at}gmail.com.
  • Citation Lee C-C, Wang J-L, Lee C-H, Hsieh C-C, Hung Y-P, Hong M-Y, Tang H-J, Ko W-C. 2017. Clinical benefit of appropriate empirical fluoroquinolone therapy for adults with community-onset bacteremia in comparison with third-generation-cephalosporin therapy. Antimicrob Agents Chemother 61:e02174-16. https://doi.org/10.1128/AAC.02174-16 .

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Clinical Benefit of Appropriate Empirical Fluoroquinolone Therapy for Adults with Community-Onset Bacteremia in Comparison with Third-Generation-Cephalosporin Therapy
Ching-Chi Lee, Jiun-Ling Wang, Chung-Hsun Lee, Chih-Chia Hsieh, Yuan-Pin Hung, Ming-Yuan Hong, Hung-Jen Tang, Wen-Chien Ko
Antimicrobial Agents and Chemotherapy Jan 2017, 61 (2) e02174-16; DOI: 10.1128/AAC.02174-16

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Clinical Benefit of Appropriate Empirical Fluoroquinolone Therapy for Adults with Community-Onset Bacteremia in Comparison with Third-Generation-Cephalosporin Therapy
Ching-Chi Lee, Jiun-Ling Wang, Chung-Hsun Lee, Chih-Chia Hsieh, Yuan-Pin Hung, Ming-Yuan Hong, Hung-Jen Tang, Wen-Chien Ko
Antimicrobial Agents and Chemotherapy Jan 2017, 61 (2) e02174-16; DOI: 10.1128/AAC.02174-16
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    • ABSTRACT
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KEYWORDS

Anti-Bacterial Agents
bacteremia
cephalosporins
community-acquired infections
fluoroquinolones
fluoroquinolone
third-generation cephalosporin
empirical therapy
community onset
bacteremia
defervescence

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