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Antiviral Agents

A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading

Vanessa Gaillard, Marie Galloux, Dominique Garcin, Jean-François Eléouët, Ronan Le Goffic, Thibaut Larcher, Marie-Anne Rameix-Welti, Abdelhak Boukadiri, Julien Héritier, Jean-Manuel Segura, Elodie Baechler, Miriam Arrell, Geneviève Mottet-Osman, Origène Nyanguile
Vanessa Gaillard
aHES-SO Valais, Sion, Switzerland
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Marie Galloux
bVIM, INRA, Université Paris-Saclay, Jouy-en-Josas, France
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Dominique Garcin
cDepartment of Microbiology and Molecular Medicine, University of Geneva School of Medicine, CMU, Geneva, Switzerland
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Jean-François Eléouët
bVIM, INRA, Université Paris-Saclay, Jouy-en-Josas, France
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Ronan Le Goffic
bVIM, INRA, Université Paris-Saclay, Jouy-en-Josas, France
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  • ORCID record for Ronan Le Goffic
Thibaut Larcher
dINRA, UMR 703 APEX, Oniris, Nantes, France
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Marie-Anne Rameix-Welti
eUMR INSERM U1173 I2, UFR des Sciences de la Santé Simone Veil—UVSQ, Montigny-Le-Bretonneux, France
fAP-HP, Laboratoire de Microbiologie, Hôpital Ambroise Paré, Boulogne-Billancourt, France
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Abdelhak Boukadiri
gUMR INRA, Génétique Animale et Biologie Intégrative, Equipe plateforme @BRIDGE, plateau d'histologie, Jouy-en-Josas, France
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Julien Héritier
aHES-SO Valais, Sion, Switzerland
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Jean-Manuel Segura
aHES-SO Valais, Sion, Switzerland
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Elodie Baechler
aHES-SO Valais, Sion, Switzerland
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Miriam Arrell
aHES-SO Valais, Sion, Switzerland
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Geneviève Mottet-Osman
cDepartment of Microbiology and Molecular Medicine, University of Geneva School of Medicine, CMU, Geneva, Switzerland
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Origène Nyanguile
aHES-SO Valais, Sion, Switzerland
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DOI: 10.1128/AAC.02241-16
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Article Information

DOI 
https://doi.org/10.1128/AAC.02241-16
PubMed 
28137809

Published By 
American Society for Microbiology Journals
History 
  • Received October 20, 2016
  • Returned for modification November 15, 2016
  • Accepted January 22, 2017
  • Published online March 24, 2017.

Copyright & Usage 
Copyright © 2017 Gaillard et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license .

Article Versions

  • Accepted Manuscript version (January 30, 2017).
  • You are viewing the most recent version of this article.

Author Information

  1. Vanessa Gaillarda,
  2. Marie Gallouxb,
  3. Dominique Garcinc,
  4. Jean-François Eléouëtb,
  5. Ronan Le Gofficb,
  6. Thibaut Larcherd,
  7. Marie-Anne Rameix-Weltie,f,
  8. Abdelhak Boukadirig,
  9. Julien Héritiera*,
  10. Jean-Manuel Seguraa,
  11. Elodie Baechlera*,
  12. Miriam Arrella*,
  13. Geneviève Mottet-Osmanc and
  14. Origène Nyanguilea
  1. aHES-SO Valais, Sion, Switzerland
  2. bVIM, INRA, Université Paris-Saclay, Jouy-en-Josas, France
  3. cDepartment of Microbiology and Molecular Medicine, University of Geneva School of Medicine, CMU, Geneva, Switzerland
  4. dINRA, UMR 703 APEX, Oniris, Nantes, France
  5. eUMR INSERM U1173 I2, UFR des Sciences de la Santé Simone Veil—UVSQ, Montigny-Le-Bretonneux, France
  6. fAP-HP, Laboratoire de Microbiologie, Hôpital Ambroise Paré, Boulogne-Billancourt, France
  7. gUMR INRA, Génétique Animale et Biologie Intégrative, Equipe plateforme @BRIDGE, plateau d'histologie, Jouy-en-Josas, France
  • Address correspondence to Origène Nyanguile, origene.nyanguile{at}hevs.ch.
  • ↵* Present address: Julien Héritier, Mediplant, Swiss Research Centre on Medicinal and Aromatic Plants, Conthey, Switzerland; Elodie Baechler, Bio-Rad Laboratories, Diamed GmbH, Cressier FR, Switzerland; Miriam Arrell, Atheris, Laboratories, Plan-les-Ouates, Switzerland.

  • Citation Gaillard V, Galloux M, Garcin D, Eléouët J-F, Le Goffic R, Larcher T, Rameix-Welti M-A, Boukadiri A, Héritier J, Segura J-M, Baechler E, Arrell M, Mottet-Osman G, Nyanguile O. 2017. A short double-stapled peptide inhibits respiratory syncytial virus entry and spreading. Antimicrob Agents Chemother 61:e02241-16. https://doi.org/10.1128/AAC.02241-16 .

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A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading
Vanessa Gaillard, Marie Galloux, Dominique Garcin, Jean-François Eléouët, Ronan Le Goffic, Thibaut Larcher, Marie-Anne Rameix-Welti, Abdelhak Boukadiri, Julien Héritier, Jean-Manuel Segura, Elodie Baechler, Miriam Arrell, Geneviève Mottet-Osman, Origène Nyanguile
Antimicrobial Agents and Chemotherapy Mar 2017, 61 (4) e02241-16; DOI: 10.1128/AAC.02241-16

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A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading
Vanessa Gaillard, Marie Galloux, Dominique Garcin, Jean-François Eléouët, Ronan Le Goffic, Thibaut Larcher, Marie-Anne Rameix-Welti, Abdelhak Boukadiri, Julien Héritier, Jean-Manuel Segura, Elodie Baechler, Miriam Arrell, Geneviève Mottet-Osman, Origène Nyanguile
Antimicrobial Agents and Chemotherapy Mar 2017, 61 (4) e02241-16; DOI: 10.1128/AAC.02241-16
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KEYWORDS

antiviral agents
peptides
Respiratory Syncytial Virus Infections
Respiratory Syncytial Virus, Human
Viral Fusion Proteins
Virus Internalization
respiratory syncytial virus
stapled peptides

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