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Susceptibility

Synergistic Activity of Colistin-Containing Combinations against Colistin-Resistant Enterobacteriaceae

Thea Brennan-Krohn, Alejandro Pironti, James E. Kirby
Thea Brennan-Krohn
aDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
bDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA
dHarvard Medical School, Boston, Massachusetts, USA
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Alejandro Pironti
cBroad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
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James E. Kirby
aDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
dHarvard Medical School, Boston, Massachusetts, USA
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DOI: 10.1128/AAC.00873-18
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Article Information

DOI 
https://doi.org/10.1128/AAC.00873-18
PubMed 
30061285

Published By 
American Society for Microbiology Journals
History 
  • Received April 28, 2018
  • Returned for modification May 18, 2018
  • Accepted July 24, 2018
  • Published online September 24, 2018.

Copyright & Usage 
Copyright © 2018 American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (July 30, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Thea Brennan-Krohna,b,d,
  2. Alejandro Pirontic and
  3. James E. Kirbya,d
  1. aDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
  2. bDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA
  3. cBroad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
  4. dHarvard Medical School, Boston, Massachusetts, USA
  • Address correspondence to James E. Kirby, jekirby{at}bidmc.harvard.edu.
  • Citation Brennan-Krohn T, Pironti A, Kirby JE. 2018. Synergistic activity of colistin-containing combinations against colistin-resistant Enterobacteriaceae. Antimicrob Agents Chemother 62:e00873-18. https://doi.org/10.1128/AAC.00873-18.

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Synergistic Activity of Colistin-Containing Combinations against Colistin-Resistant Enterobacteriaceae
Thea Brennan-Krohn, Alejandro Pironti, James E. Kirby
Antimicrobial Agents and Chemotherapy Sep 2018, 62 (10) e00873-18; DOI: 10.1128/AAC.00873-18

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Synergistic Activity of Colistin-Containing Combinations against Colistin-Resistant Enterobacteriaceae
Thea Brennan-Krohn, Alejandro Pironti, James E. Kirby
Antimicrobial Agents and Chemotherapy Sep 2018, 62 (10) e00873-18; DOI: 10.1128/AAC.00873-18
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KEYWORDS

CRE
Enterobacteriaceae
mcr-1
NDM-1
carbapenem-resistant Enterobacteriaceae
checkerboard
colistin
synergy
time-kill curves

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