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Clinical Therapeutics

Impact of Efavirenz-, Ritonavir-Boosted Lopinavir-, and Nevirapine-Based Antiretroviral Regimens on the Pharmacokinetics of Lumefantrine and Safety of Artemether-Lumefantrine in Plasmodium falciparum-Negative HIV-Infected Malawian Adults Stabilized on Antiretroviral Therapy

Clifford G. Banda, Fraction Dzinjalamala, Mavuto Mukaka, Jane Mallewa, Victor Maiden, Dianne J. Terlouw, David G. Lalloo, Saye H. Khoo, Victor Mwapasa
Clifford G. Banda
University of Malawi, College of Medicine, Blantyre, MalawiMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
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  • ORCID record for Clifford G. Banda
Fraction Dzinjalamala
University of Malawi, College of Medicine, Blantyre, MalawiMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
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Mavuto Mukaka
University of Malawi, College of Medicine, Blantyre, MalawiOxford Centre for Tropical Medicine and Global Health, Oxford, United KingdomMahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand
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Jane Mallewa
University of Malawi, College of Medicine, Blantyre, MalawiMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
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Victor Maiden
Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
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Dianne J. Terlouw
Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, MalawiLiverpool School of Tropical Medicine, Liverpool, United Kingdom
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David G. Lalloo
Liverpool School of Tropical Medicine, Liverpool, United Kingdom
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Saye H. Khoo
University of Liverpool, Liverpool, United Kingdom
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Victor Mwapasa
University of Malawi, College of Medicine, Blantyre, MalawiMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
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DOI: 10.1128/AAC.01162-18
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Article Information

DOI 
https://doi.org/10.1128/AAC.01162-18
PubMed 
30150465

Published By 
American Society for Microbiology Journals
History 
  • Received June 1, 2018
  • Returned for modification July 13, 2018
  • Accepted August 11, 2018
  • Published online October 24, 2018.

Copyright & Usage 
Copyright © 2018 Banda et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Article Versions

  • Accepted Manuscript version (August 27, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Clifford G. Bandaa,b,
  2. Fraction Dzinjalamalaa,b,
  3. Mavuto Mukakaa,c,f,
  4. Jane Mallewaa,b,
  5. Victor Maidenb,
  6. Dianne J. Terlouwb,d,
  7. David G. Lallood,
  8. Saye H. Khooe and
  9. Victor Mwapasaa,b
  1. aUniversity of Malawi, College of Medicine, Blantyre, Malawi
  2. bMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
  3. cOxford Centre for Tropical Medicine and Global Health, Oxford, United Kingdom
  4. dLiverpool School of Tropical Medicine, Liverpool, United Kingdom
  5. eUniversity of Liverpool, Liverpool, United Kingdom
  6. fMahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand
  • Address correspondence to Clifford G. Banda, cgbanda{at}mlw.mw, or Victor Mwapasa, vmwapasa{at}medcol.mw.
  • Citation Banda CG, Dzinjalamala F, Mukaka M, Mallewa J, Maiden V, Terlouw DJ, Lalloo DG, Khoo SH, Mwapasa V. 2018. Impact of efavirenz-, ritonavir-boosted lopinavir-, and nevirapine-based antiretroviral regimens on the pharmacokinetics of lumefantrine and safety of artemether-lumefantrine in Plasmodium falciparum-negative HIV-infected Malawian adults stabilized on antiretroviral therapy. Antimicrob Agents Chemother 62:e01162-18. https://doi.org/10.1128/AAC.01162-18.

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Impact of Efavirenz-, Ritonavir-Boosted Lopinavir-, and Nevirapine-Based Antiretroviral Regimens on the Pharmacokinetics of Lumefantrine and Safety of Artemether-Lumefantrine in Plasmodium falciparum-Negative HIV-Infected Malawian Adults Stabilized on Antiretroviral Therapy
Clifford G. Banda, Fraction Dzinjalamala, Mavuto Mukaka, Jane Mallewa, Victor Maiden, Dianne J. Terlouw, David G. Lalloo, Saye H. Khoo, Victor Mwapasa
Antimicrobial Agents and Chemotherapy Oct 2018, 62 (11) e01162-18; DOI: 10.1128/AAC.01162-18

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Impact of Efavirenz-, Ritonavir-Boosted Lopinavir-, and Nevirapine-Based Antiretroviral Regimens on the Pharmacokinetics of Lumefantrine and Safety of Artemether-Lumefantrine in Plasmodium falciparum-Negative HIV-Infected Malawian Adults Stabilized on An…
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Impact of Efavirenz-, Ritonavir-Boosted Lopinavir-, and Nevirapine-Based Antiretroviral Regimens on the Pharmacokinetics of Lumefantrine and Safety of Artemether-Lumefantrine in Plasmodium falciparum-Negative HIV-Infected Malawian Adults Stabilized on Antiretroviral Therapy
Clifford G. Banda, Fraction Dzinjalamala, Mavuto Mukaka, Jane Mallewa, Victor Maiden, Dianne J. Terlouw, David G. Lalloo, Saye H. Khoo, Victor Mwapasa
Antimicrobial Agents and Chemotherapy Oct 2018, 62 (11) e01162-18; DOI: 10.1128/AAC.01162-18
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KEYWORDS

artemether-lumefantrine
antiretroviral therapy
malaria
antimalarial agents

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