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Pharmacology

Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections

Sheryl A. Zelenitsky, Divna Calic, Rakesh C. Arora, Hilary P. Grocott, Ted M. Lakowski, Ryan Lillico, Robert E. Ariano
Sheryl A. Zelenitsky
College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Pharmacy, St. Boniface Hospital, Winnipeg, Manitoba, Canada
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  • ORCID record for Sheryl A. Zelenitsky
Divna Calic
College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
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Rakesh C. Arora
Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, CanadaCardiac Sciences Program, St. Boniface Hospital, Winnipeg, Manitoba, Canada
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Hilary P. Grocott
Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, CanadaCardiac Sciences Program, St. Boniface Hospital, Winnipeg, Manitoba, Canada
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Ted M. Lakowski
College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, CanadaPharmaceutical Analysis Laboratory, College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
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Ryan Lillico
College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
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Robert E. Ariano
College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Pharmacy, St. Boniface Hospital, Winnipeg, Manitoba, Canada
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DOI: 10.1128/AAC.01360-18
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Article Information

DOI 
https://doi.org/10.1128/AAC.01360-18
PubMed 
30150469

Published By 
American Society for Microbiology Journals
History 
  • Received June 26, 2018
  • Returned for modification July 16, 2018
  • Accepted August 20, 2018
  • Published online October 24, 2018.

Copyright & Usage 
Copyright © 2018 American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (August 27, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Sheryl A. Zelenitskya,b,
  2. Divna Calica,
  3. Rakesh C. Arorac,d,
  4. Hilary P. Grocottc,d,
  5. Ted M. Lakowskia,e,
  6. Ryan Lillicoa and
  7. Robert E. Arianoa,b
  1. aCollege of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
  2. bDepartment of Pharmacy, St. Boniface Hospital, Winnipeg, Manitoba, Canada
  3. cMax Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
  4. dCardiac Sciences Program, St. Boniface Hospital, Winnipeg, Manitoba, Canada
  5. ePharmaceutical Analysis Laboratory, College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
  • Address correspondence to Sheryl A. Zelenitsky, zelenits{at}umanitoba.ca.
  • Citation Zelenitsky SA, Calic D, Arora RC, Grocott HP, Lakowski TM, Lillico R, Ariano RE. 2018. Antimicrobial prophylaxis for patients undergoing cardiac surgery: intraoperative cefazolin concentrations and sternal wound infections. Antimicrob Agents Chemother 62:e01360-18. https://doi.org/10.1128/AAC.01360-18.

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Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections
Sheryl A. Zelenitsky, Divna Calic, Rakesh C. Arora, Hilary P. Grocott, Ted M. Lakowski, Ryan Lillico, Robert E. Ariano
Antimicrobial Agents and Chemotherapy Oct 2018, 62 (11) e01360-18; DOI: 10.1128/AAC.01360-18

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Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections
Sheryl A. Zelenitsky, Divna Calic, Rakesh C. Arora, Hilary P. Grocott, Ted M. Lakowski, Ryan Lillico, Robert E. Ariano
Antimicrobial Agents and Chemotherapy Oct 2018, 62 (11) e01360-18; DOI: 10.1128/AAC.01360-18
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KEYWORDS

surgical prophylaxis
cefazolin
pharmacodynamics
cardiac surgery
surgical site infection
wound infection

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