DOI: 10.1128/AAC.01776-17
Article Figures & Data
Tables
- TABLE 1
In vitro susceptibilities of the Corynebacterium isolates received at the PHOL from 2011 to 2016
Antimicrobial agent by organism No. of isolates MIC range MIC50 MIC90 % Sa All Corynebacterium spp. 1,970 Penicillin 1,970 ≤0.06 to >8 4 >8 14.5 Ampicillin 1,969 ≤0.12 to >8 2 >8 ND Oxacillin 1,969 ≤0.25 to >4 >4 >4 ND Erythromycin 1,970 ≤0.25 to >4 >4 >4 15.1 Clindamycin 1,958 ≤0.5 to >2 >2 >2 8.7 Ciprofloxacin 1,959 ≤1 to >2 >2 >2 26.9 Levofloxacin 1,968 ≤0.25 to >4 >4 >4 ND Moxifloxacinb 1,968 ≤0.25 to >4 >4 >4 27.7 Tetracycline 1,969 ≤2 to >16 ≤2 >16 64.2 Vancomycin 1,970 ≤0.25 to 2 0.5 0.5 100 Trimethoprim-sulfamethoxazole 1,967 ≤0.5 to >4 4 >4 38.1 Tigecycline 1,967 ≤0.03 to >0.5 0.12 0.25 ND Rifampin 1,968 ≤0.5 to>4 ≤0.5 ≤0.5 91.4 Quinupristin-dalfopristin 1,969 ≤0.5 to >4 ≤0.5 1 93.3 Linezolid 1,969 ≤1 to 2 ≤1 ≤1 100 Gentamicin 1,970 ≤2 to >16 ≤2 4 93.3 Daptomycin 1,959 ≤0.5 to >4 ≤0.5 ≤0.5 97.7 Chloramphenicol 1,960 ≤2 to >16 4 >16 ND Nitrofurantoin 1,969 ≤32 to >64 >64 >64 ND C. striatum 931 Penicillin 931 ≤0.06 to >8 8 >8 0.1 Ampicillin 930 ≤0.12 to >8 4 >8 ND Oxacillin 930 ≤0.25 to >4 >4 >4 ND Erythromycin 931 ≤0.25to >4 >4 >4 14.6 Clindamycin 922 ≤0.5 to >2 >2 >2 5.4 Ciprofloxacin 926 ≤1 to >2 >2 >2 4.6 Levofloxacin 930 ≤0.25 to >4 >4 >4 ND Moxifloxacinb 929 ≤0.25 to >4 >4 >4 5.2 Tetracycline 930 ≤2 to >16 >16 >16 34.7 Vancomycin 931 ≤0.25 to 1 0.5 0.5 100 Trimethoprim-sulfamethoxazole 928 ≤0.5 to >4 >4 >4 11.5 Tigecycline 929 ≤0.03 to >0.5 0.12 0.25 ND Rifampin 930 ≤0.5 to >4 ≤0.5 >4 85.6 Quinupristin-dalfopristin 930 ≤0.5 to 2 ≤0.5 ≤0.5 99.4 Linezolid 930 ≤1 ≤1 ≤1 100 Gentamicin 931 ≤2 to >16 ≤2 4 92.8 Daptomycin 924 ≤0.5 to>4 ≤0.5 ≤0.5 98 Chloramphenicol 924 ≤2 to >16 ≤2 16 ND Nitrofurantoin 930 ≤32 to >64 >64 >64 ND C. amycolatum 190 Penicillin 190 ≤0.06 to >8 1 >8 10.5 Ampicillin 190 ≤0.12 to >8 1 >8 ND Oxacillin 190 ≤0.25 to >4 >4 >4 ND Erythromycin 190 ≤0.25 to >4 >4 >4 15.8 Clindamycin 189 ≤0.5 to>2 >2 >2 20.5 Ciprofloxacin 189 ≤1 to >2 >2 >2 26.8 Levofloxacin 190 ≤0.25 to >4 >4 >4 ND Moxifloxacinb 190 ≤0.25 to >4 4 >4 27.4 Tetracycline 190 ≤2 to >16 ≤2 16 85.8 Vancomycin 190 ≤0.25 to 1 0.5 0.5 100 Trimethoprim-sulfamethoxazole 190 ≤0.5 to >4 1 >4 66.8 Tigecycline 189 ≤0.03 to >0.5 0.12 0.25 ND Rifampin 190 ≤0.5 to >4 ≤0.5 ≤0.5 98.4 Quinupristin-dalfopristin 190 ≤0.5 to 2 ≤0.5 ≤0.5 99.5 Linezolid 190 ≤1 ≤1 ≤1 100 Gentamicin 190 ≤2 to >16 ≤2 4 93.2 Daptomycin 190 ≤0.5 to 2 ≤0.5 ≤0.5 99.5 Chloramphenicol 189 ≤2 to >16 ≤2 16 ND Nitrofurantoin 190 ≤32 to >64 >64 >64 ND C. pseudodiphtheriticum/C. propinquum 216 Penicillin 216 ≤0.06 to 4 ≤0.06 ≤0.06 95.8 Ampicillin 216 ≤0.12 to 4 ≤0.12 ≤0.12 ND Oxacillin 216 ≤0.25 to >4 0.5 1 ND Erythromycin 216 ≤0.25 to >4 >4 >4 21.3 Clindamycin 216 ≤0.5 to >2 >2 >2 20.8 Ciprofloxacin 216 ≤1 to >2 ≤1 >2 78.7 Levofloxacin 216 ≤0.25 to >4 1 >4 ND Moxifloxacinb 216 ≤0.25 to >4 ≤0.25 >4 79.2 Tetracycline 216 ≤2 to >16 ≤2 ≤2 98.6 Vancomycin 216 ≤0.25 to 2 0.5 0.5 100 Trimethoprim-sulfamethoxazole 216 ≤0.5 to >4 ≤0.5 4 87.5 Tigecycline 216 ≤0.03 to >0.5 0.06 0.25 ND Rifampin 216 ≤0.5 to 1 ≤0.5 ≤0.5 100 Quinupristin-dalfopristin 216 ≤0.5 to 1 ≤0.5 ≤0.5 100 Linezolid 216 ≤1 to 2 ≤1 ≤1 100 Gentamicin 216 ≤2 ≤2 ≤2 100 Daptomycin 216 ≤0.5 to >4 ≤0.5 ≤0.5 99.5 Chloramphenicol 216 ≤2 to >16 4 >16 ND Nitrofurantoin 216 ≤32 to >64 >64 >64 ND C. afermentans subsp. afermentans 89 Penicillin 89 ≤0.06 to >8 4 >8 1.12 Ampicillin 89 ≤0.12 to >8 4 8 ND Oxacillin 89 ≤0.25 to >4 >4 >4 ND Erythromycin 89 2 to >4 >4 >4 0 Clindamycin 89 1 to >2 >2 >2 0 Ciprofloxacin 89 ≤1 to >2 >2 >2 30.3 Levofloxacin 89 ≤0.25 to >4 >4 >4 ND Moxifloxacinb 89 ≤0.25 to >4 >4 >4 31.5 Tetracycline 89 ≤2 to >16 ≤2 8 87.6 Vancomycin 89 ≤0.25 to 1 ≤0.25 0.50 100 Trimethoprim-sulfamethoxazole 89 ≤0.5 to>4 2 >4 55.1 Tigecycline 89 ≤0.03 to >0.5 0.12 0.25 ND Rifampin 89 ≤0.5 to >4 ≤0.5 ≤0.5 94.4 Quinupristin-dalfopristin 89 ≤0.5 to >4 1 4 51.7 Linezolid 89 ≤1 to 2 ≤1 ≤1 100 Gentamicin 89 ≤2 to >16 ≤2 ≤2 98.9 Daptomycin 89 ≤0.5 to 4 ≤0.5 ≤0.5 97.8 Chloramphenicol 89 ≤2 to >16 8 >16 ND Nitrofurantoin 89 ≤32 to >64 >64 >64 ND C. jeikeium 76 Penicillin 76 0.5 to >8 >8 >8 0 Ampicillin 76 ≤0.12 to >8 >8 >8 ND Oxacillin 76 0.5 to >4 >4 >4 ND Erythromycin 76 ≤0.25 to >4 >4 >4 11.8 Clindamycin 76 ≤0.5 to >2 >2 >2 2.6 Ciprofloxacin 75 ≤1 to >2 >2 >2 35.5 Levofloxacin 75 ≤0.25 to >4 >4 >4 ND Moxifloxacinb 76 ≤0.25 to >4 4 >4 35.5 Tetracycline 76 ≤2 to >16 ≤2 ≤2 92.1 Vancomycin 76 ≤0.25 to 2 0.50 1 100 Trimethoprim-sulfamethoxazole 76 ≤0.5 to >4 >4 >4 18.4 Tigecycline 76 ≤0.03 to >0.5 0.12 0.25 ND Rifampin 76 ≤0.5 to >4 ≤0.5 ≤0.5 97.4 Quinupristin-dalfopristin 76 ≤0.5 to 4 ≤0.5 2 89.5 Linezolid 76 ≤1 ≤1 ≤1 100 Gentamicin 76 ≤2 to >16 ≤2 >16 81.6 Daptomycin 75 ≤0.5 to >4 ≤0.5 1 89.5 Chloramphenicol 75 ≤2 to >16 4 16 ND Nitrofurantoin 76 ≤32 to >64 >64 >64 ND C. minutissimum 76 Penicillin 76 ≤0.06 to >8 1 8 3.9 Ampicillin 76 ≤0.12 to >8 1 4 ND Oxacillin 76 2 to >4 >4 >4 ND Erythromycin 76 ≤0.25 to >4 >4 >4 19.7 Clindamycin 76 ≤0.5 to >2 >2 >2 1.3 Ciprofloxacin 74 ≤1 to >2 ≤1 >2 55.3 Levofloxacin 76 ≤0.25 to >4 ≤0.25 >4 ND Moxifloxacinb 76 ≤0.25 to >4 ≤0.25 >4 61.8 Tetracycline 76 ≤2 to >16 ≤2 4 92.1 Vancomycin 76 ≤0.25 to 1 0.50 0.50 100 Trimethoprim-sulfamethoxazole 76 ≤0.5 to >4 2 >4 61.8 Tigecycline 76 ≤0.03 to >0.5 0.06 0.25 ND Rifampin 75 ≤0.5 to >4 ≤0.5 ≤0.5 96.1 Quinupristin-dalfopristin 76 ≤0.5 to 4 ≤0.5 1 93.4 Linezolid 76 ≤1 to >8 ≤1 ≤1 98.7 Gentamicin 76 ≤2 to >16 ≤2 ≤2 96.1 Daptomycin 75 ≤0.5 to >4 ≤0.5 1 92.1 Chloramphenicol 75 ≤2 to >16 4 8 ND Nitrofurantoin 76 ≤32 to >64 64 >64 ND C. coyleae 58 Penicillin 58 ≤0.06 to >8 4 >8 1.7 Ampicillin 58 ≤0.12 to >8 4 8 ND Oxacillin 58 2 to >4 >4 >4 ND Erythromycin 58 ≤0.25 to >4 >4 >4 3.5 Clindamycin 58 ≤0.5 to >2 >2 >2 3.5 Ciprofloxacin 57 ≤1 to >2 >2 >2 27.6 Levofloxacin 58 ≤0.25 to >4 >4 >4 ND Moxifloxacinb 58 ≤0.25 to >4 4 >4 29.3 Tetracycline 58 ≤2 to >16 ≤2 ≤2 93.1 Vancomycin 58 ≤0.25 to 2 0.5 0.50 100 Trimethoprim-sulfamethoxazole 58 ≤0.5 to >4 4 >4 48.3 Tigecycline 58 ≤0.03 to >0.5 0.06 0.25 ND Rifampin 58 ≤0.5 to >4 ≤0.5 ≤0.5 91.4 Quinupristin-dalfopristin 58 ≤0.5 to 4 2 4 43.1 Linezolid 58 ≤1 to 2 ≤1 ≤1 100 Gentamicin 58 ≤2 ≤2 ≤2 100 Daptomycin 57 ≤0.5 to >4 ≤0.5 ≤0.5 93 Chloramphenicol 58 ≤2 to >16 4 >16 ND Nitrofurantoin 58 ≤32 to >64 >64 >64 ND C. urealyticum 52 Penicillin 52 0.12 to >8 >8 >8 3.8 Ampicillin 52 ≤0.12 to >8 >8 >8 ND Oxacillin 52 1 to >4 >4 >4 ND Erythromycin 52 ≤0.25 to >4 >4 >4 1.9 Clindamycin 51 ≤0.5 to >2 >2 >2 3.8 Ciprofloxacin 51 ≤1 to >2 >2 >2 3.8 Levofloxacin 52 ≤0.25 to >4 >4 >4 ND Moxifloxacinb 52 ≤0.25 to >4 >4 >4 3.8 Tetracycline 52 ≤2 to >16 ≤2 ≤2 92.3 Vancomycin 52 ≤0.25 to 2 0.50 1 100 Trimethoprim-sulfamethoxazole 52 ≤0.5 to >4 >4 >4 1.9 Tigecycline 52 ≤0.03 to >0.5 0.06 0.12 ND Rifampin 52 ≤0.5 to >4 ≤0.5 ≤0.5 92.3 Quinupristin-dalfopristin 52 ≤0.5 to 1 ≤0.5 ≤0.5 100 Linezolid 52 ≤1 ≤1 ≤1 100 Gentamicin 52 ≤2 to >16 ≤2 >16 55.7 Daptomycin 51 ≤0.5 ≤0.5 ≤0.5 100 Chloramphenicol 52 ≤2 to >16 8 >16 ND Nitrofurantoin 52 >64 >64 >64 ND C. aurimucosum 51 Penicillin 51 0.12 to >8 1 >8 5.8 Ampicillin 51 0.25 to >8 1 8 ND Oxacillin 51 2 to >4 >4 >4 ND Erythromycin 51 ≤0.25 to >4 >4 >4 11.7 Clindamycin 51 1 to >2 >2 >2 0 Ciprofloxacin 51 ≤1 to >2 >2 >2 43.1 Levofloxacin 51 ≤0.25 to >4 4 >4 ND Moxifloxacinb 51 ≤0.25 to >4 2 >4 43.1 Tetracycline 51 ≤2 to >16 ≤2 4 90.2 Vancomycin 51 ≤0.25 to 1 0.50 0.50 100 Trimethoprim-sulfamethoxazole 51 ≤0.5 to >4 2 >4 62.7 Tigecycline 51 ≤0.03 to 0.25 0.06 0.12 ND Rifampin 51 ≤0.5 ≤0.5 ≤0.5 100 Quinupristin-dalfopristin 51 ≤0.5 to 4 ≤0.5 1 92.2 Linezolid 51 ≤1 ≤1 ≤1 100 Gentamicin 51 ≤2 to 4 ≤2 ≤2 100 Daptomycin 51 ≤0.5 to 3 ≤0.5 ≤0.5 98 Chloramphenicol 51 ≤2 to >16 4 8 ND Nitrofurantoin 51 ≤32 to >64 64 >64 ND
Additional Files
Supplemental material
- Supplemental file 1 -
Tables S1 and S2
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- Supplemental file 2 -
Data Set S1
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- Supplemental file 1 -
