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Mechanisms of Action: Physiological Effects

Leishmania donovani Parasites Are Inhibited by the Benzoxaborole AN2690 Targeting Leucyl-tRNA Synthetase

Reetika Manhas, Smriti Tandon, Shib Sankar Sen, Neha Tiwari, Manoj Munde, Rentala Madhubala
Reetika Manhas
aSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India
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Smriti Tandon
aSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India
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Shib Sankar Sen
aSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India
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Neha Tiwari
bSchool of Physical Sciences, Jawaharlal Nehru University, New Delhi, India
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Manoj Munde
bSchool of Physical Sciences, Jawaharlal Nehru University, New Delhi, India
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Rentala Madhubala
aSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India
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DOI: 10.1128/AAC.00079-18
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Article Information

DOI 
https://doi.org/10.1128/AAC.00079-18
PubMed 
29941647

Published By 
American Society for Microbiology Journals
History 
  • Received January 15, 2018
  • Returned for modification March 12, 2018
  • Accepted June 15, 2018
  • Published online August 27, 2018.

Copyright & Usage 
Copyright © 2018 American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (June 25, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Reetika Manhasa,
  2. Smriti Tandona,
  3. Shib Sankar Sena,
  4. Neha Tiwarib,
  5. Manoj Mundeb and
  6. Rentala Madhubalaa
  • Address correspondence to Rentala Madhubala, rentala{at}outlook.com.
  • R.M. and S.T. contributed equally to this article.

  • Citation Manhas R, Tandon S, Sen SS, Tiwari N, Munde M, Madhubala R. 2018. Leishmania donovani parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase. Antimicrob Agents Chemother 62:e00079-18. https://doi.org/10.1128/AAC.00079-18.

  1. aSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India
  2. bSchool of Physical Sciences, Jawaharlal Nehru University, New Delhi, India

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Leishmania donovani Parasites Are Inhibited by the Benzoxaborole AN2690 Targeting Leucyl-tRNA Synthetase
Reetika Manhas, Smriti Tandon, Shib Sankar Sen, Neha Tiwari, Manoj Munde, Rentala Madhubala
Antimicrobial Agents and Chemotherapy Aug 2018, 62 (9) e00079-18; DOI: 10.1128/AAC.00079-18

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Leishmania donovani Parasites Are Inhibited by the Benzoxaborole AN2690 Targeting Leucyl-tRNA Synthetase
Reetika Manhas, Smriti Tandon, Shib Sankar Sen, Neha Tiwari, Manoj Munde, Rentala Madhubala
Antimicrobial Agents and Chemotherapy Aug 2018, 62 (9) e00079-18; DOI: 10.1128/AAC.00079-18
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KEYWORDS

leucyl-tRNA synthetase
Leishmania donovani
null mutant
AN2690
antileishmanial

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