DOI: 10.1128/AAC.00992-19
ABSTRACT
A pan-susceptible Salmonella enterica serovar Worthington isolate was detected in the stool of a man returning from Sri Lanka. Under ceftriaxone treatment, a third-generation cephalosporin (3GC)-resistant Salmonella Worthington was isolated after 8 days. Molecular analyses indicated that the two isolates were identical. However, the latter strain acquired a blaDHA-1-carrying IncFII plasmid probably from a Citrobacter amalonaticus isolate colonizing the gut. This is the first report of in vivo acquisition of plasmid-mediated resistance to 3GCs in S. enterica.
FOOTNOTES
- Received 15 May 2019.
- Returned for modification 7 June 2019.
- Accepted 24 July 2019.
- Accepted manuscript posted online 29 July 2019.
Supplemental material for this article may be found at https://doi.org/10.1128/AAC.00992-19.
- Copyright © 2019 American Society for Microbiology.
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