Skip to main content
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems
  • Log in
  • My alerts
  • My Cart

Main menu

  • Home
  • Articles
    • Current Issue
    • Accepted Manuscripts
    • COVID-19 Special Collection
    • Archive
    • Minireviews
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About AAC
    • Editor in Chief
    • Editorial Board
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • AAC Podcast
    • RSS
    • FAQ
  • Subscribe
    • Members
    • Institutions
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems

User menu

  • Log in
  • My alerts
  • My Cart

Search

  • Advanced search
Antimicrobial Agents and Chemotherapy
publisher-logosite-logo

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Accepted Manuscripts
    • COVID-19 Special Collection
    • Archive
    • Minireviews
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About AAC
    • Editor in Chief
    • Editorial Board
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • AAC Podcast
    • RSS
    • FAQ
  • Subscribe
    • Members
    • Institutions
Clinical Therapeutics

A First-in-Human Safety, Tolerability, and Pharmacokinetics Study of Benapenem in Healthy Chinese Volunteers

Cai-Yun Zhao, Yuan Lv, Yan Zhu, Min-Ji Wei, Meng-Ying Liu, Xi-Wei Ji, Zi-Sheng Kang, Ya-Hong Xia, Ji-Hong Tian, Yan Ma, Yan Liu
Cai-Yun Zhao
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yuan Lv
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yan Zhu
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Min-Ji Wei
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Meng-Ying Liu
bBeijing Sihuan Pharmaceuticals Co., Ltd., Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xi-Wei Ji
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Zi-Sheng Kang
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ya-Hong Xia
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ji-Hong Tian
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yan Ma
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yan Liu
aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
DOI: 10.1128/AAC.02188-18
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1128/AAC.02188-18
PubMed 
30617093

Published By 
American Society for Microbiology Journals
History 
  • Received October 17, 2018
  • Returned for modification November 19, 2018
  • Accepted January 4, 2019
  • Published online February 26, 2019.

Copyright & Usage 
Copyright © 2019 American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (January 07, 2019).
  • You are viewing the most recent version of this article.

Author Information

  1. Cai-Yun Zhaoa,
  2. Yuan Lva,
  3. Yan Zhua,
  4. Min-Ji Weia,
  5. Meng-Ying Liub,
  6. Xi-Wei Jia,
  7. Zi-Sheng Kanga,
  8. Ya-Hong Xiaa,
  9. Ji-Hong Tiana,
  10. Yan Maa and
  11. Yan Liua
  1. aInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China
  2. bBeijing Sihuan Pharmaceuticals Co., Ltd., Beijing, China
  • Address correspondence to Yuan Lv, lyzx5857{at}163.com.
  • Citation Zhao C-Y, Lv Y, Zhu Y, Wei M-J, Liu M-Y, Ji X-W, Kang Z-S, Xia Y-H, Tian J-H, Ma Y, Liu Y. 2019. A first-in-human safety, tolerability, and pharmacokinetics study of benapenem in healthy Chinese volunteers. Antimicrob Agents Chemother 63:e02188-18. https://doi.org/10.1128/AAC.02188-18.

Article usage

Article usage: January 2019 to February 2021

Rendering graph...
AbstractFullPdf
Jan 2019419021
Feb 20195743713
Mar 201939627819
Apr 201953914
May 20195458
Jun 201931157
Jul 20191645
Aug 2019856
Sep 201921710
Oct 2019588
Nov 20190168
Dec 2019152
Jan 202051011
Feb 202001610
Mar 202002114
Apr 202003011
May 20201166
Jun 20200115
Jul 202002716
Aug 2020184
Sep 202011211
Oct 202051627
Nov 202083421
Dec 202032615
Jan 202121113
Feb 20210108
PreviousNext
Back to top
Download PDF
Citation Tools
A First-in-Human Safety, Tolerability, and Pharmacokinetics Study of Benapenem in Healthy Chinese Volunteers
Cai-Yun Zhao, Yuan Lv, Yan Zhu, Min-Ji Wei, Meng-Ying Liu, Xi-Wei Ji, Zi-Sheng Kang, Ya-Hong Xia, Ji-Hong Tian, Yan Ma, Yan Liu
Antimicrobial Agents and Chemotherapy Feb 2019, 63 (3) e02188-18; DOI: 10.1128/AAC.02188-18

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Print

Alerts
Sign In to Email Alerts with your Email Address
Email

Thank you for sharing this Antimicrobial Agents and Chemotherapy article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
A First-in-Human Safety, Tolerability, and Pharmacokinetics Study of Benapenem in Healthy Chinese Volunteers
(Your Name) has forwarded a page to you from Antimicrobial Agents and Chemotherapy
(Your Name) thought you would be interested in this article in Antimicrobial Agents and Chemotherapy.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
A First-in-Human Safety, Tolerability, and Pharmacokinetics Study of Benapenem in Healthy Chinese Volunteers
Cai-Yun Zhao, Yuan Lv, Yan Zhu, Min-Ji Wei, Meng-Ying Liu, Xi-Wei Ji, Zi-Sheng Kang, Ya-Hong Xia, Ji-Hong Tian, Yan Ma, Yan Liu
Antimicrobial Agents and Chemotherapy Feb 2019, 63 (3) e02188-18; DOI: 10.1128/AAC.02188-18
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Top
  • Article
    • ABSTRACT
    • INTRODUCTION
    • RESULTS
    • DISCUSSION
    • MATERIALS AND METHODS
    • ACKNOWLEDGMENTS
    • FOOTNOTES
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • PDF

KEYWORDS

benapenem
healthy Chinese volunteers
multiple dose
pharmacokinetics
safety
single dose
tolerance

Related Articles

Cited By...

About

  • About AAC
  • Editor in Chief
  • Editorial Board
  • Policies
  • For Reviewers
  • For the Media
  • For Librarians
  • For Advertisers
  • Alerts
  • AAC Podcast
  • RSS
  • FAQ
  • Permissions
  • Journal Announcements

Authors

  • ASM Author Center
  • Submit a Manuscript
  • Article Types
  • Ethics
  • Contact Us

Follow #AACJournal

@ASMicrobiology

       

ASM Journals

ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology.

About ASM | Contact Us | Press Room

 

ASM is a member of

Scientific Society Publisher Alliance

 

American Society for Microbiology
1752 N St. NW
Washington, DC 20036
Phone: (202) 737-3600

Copyright © 2021 American Society for Microbiology | Privacy Policy | Website feedback

Print ISSN: 0066-4804; Online ISSN: 1098-6596