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Mechanisms of Resistance

Role of Viscoelasticity in Bacterial Killing by Antimicrobials in Differently Grown Pseudomonas aeruginosa Biofilms

René T. Rozenbaum, Henny C. van der Mei, Willem Woudstra, Ed D. de Jong, Henk J. Busscher, Prashant K. Sharma
René T. Rozenbaum
aDepartment of Biomedical Engineering, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
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Henny C. van der Mei
aDepartment of Biomedical Engineering, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
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Willem Woudstra
aDepartment of Biomedical Engineering, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
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Ed D. de Jong
aDepartment of Biomedical Engineering, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
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Henk J. Busscher
aDepartment of Biomedical Engineering, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
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Prashant K. Sharma
aDepartment of Biomedical Engineering, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
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DOI: 10.1128/AAC.01972-18
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Article Information

DOI 
https://doi.org/10.1128/AAC.01972-18
PubMed 
30745390

Published By 
American Society for Microbiology Journals
History 
  • Received September 18, 2018
  • Returned for modification November 28, 2018
  • Accepted December 28, 2018
  • Published online March 27, 2019.

Copyright & Usage 
Copyright © 2019 American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (February 11, 2019).
  • You are viewing the most recent version of this article.

Author Information

  1. René T. Rozenbauma,
  2. Henny C. van der Meia,
  3. Willem Woudstraa,
  4. Ed D. de Jonga,
  5. Henk J. Busschera and
  6. Prashant K. Sharmaa
  1. aDepartment of Biomedical Engineering, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands
  • Address correspondence to Prashant K. Sharma, p.k.sharma{at}umcg.nl.
  • Citation Rozenbaum RT, van der Mei HC, Woudstra W, de Jong ED, Busscher HJ, Sharma PK. 2019. Role of viscoelasticity in bacterial killing by antimicrobials in differently grown Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother 63:e01972-18. https://doi.org/10.1128/AAC.01972-18.

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Role of Viscoelasticity in Bacterial Killing by Antimicrobials in Differently Grown Pseudomonas aeruginosa Biofilms
René T. Rozenbaum, Henny C. van der Mei, Willem Woudstra, Ed D. de Jong, Henk J. Busscher, Prashant K. Sharma
Antimicrobial Agents and Chemotherapy Mar 2019, 63 (4) e01972-18; DOI: 10.1128/AAC.01972-18

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Role of Viscoelasticity in Bacterial Killing by Antimicrobials in Differently Grown Pseudomonas aeruginosa Biofilms
René T. Rozenbaum, Henny C. van der Mei, Willem Woudstra, Ed D. de Jong, Henk J. Busscher, Prashant K. Sharma
Antimicrobial Agents and Chemotherapy Mar 2019, 63 (4) e01972-18; DOI: 10.1128/AAC.01972-18
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KEYWORDS

Pseudomonas aeruginosa
biofilm
recalcitrance
viscoelasticity

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