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Antiviral Agents

Repurposing Quinacrine against Ebola Virus Infection In Vivo

Thomas R. Lane, Jason E. Comer, Alexander N. Freiberg, Peter B. Madrid, Sean Ekins
Thomas R. Lane
aCollaborations Pharmaceuticals, Inc., Raleigh, North Carolina, USA
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Jason E. Comer
bDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA
cInstitutional Office of Regulated Nonclinical Studies, University of Texas Medical Branch, Galveston, Texas, USA
dDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
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Alexander N. Freiberg
dDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
eSealy Institute for Vaccine Sciences, University of Texas Medical Branch, Galveston, Texas, USA
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Peter B. Madrid
fBioscience Division, SRI International, Menlo Park, California, USA
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Sean Ekins
aCollaborations Pharmaceuticals, Inc., Raleigh, North Carolina, USA
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DOI: 10.1128/AAC.01142-19
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Article Information

DOI 
https://doi.org/10.1128/AAC.01142-19
PubMed 
31307979

Published By 
American Society for Microbiology Journals
History 
  • Received June 3, 2019
  • Returned for modification June 26, 2019
  • Accepted July 2, 2019
  • Published online August 23, 2019.

Copyright & Usage 
Copyright © 2019 American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (July 15, 2019).
  • You are viewing the most recent version of this article.

Author Information

  1. Thomas R. Lanea,
  2. Jason E. Comerb,c,d,
  3. Alexander N. Freibergd,e,
  4. Peter B. Madridf and
  5. Sean Ekinsa
  1. aCollaborations Pharmaceuticals, Inc., Raleigh, North Carolina, USA
  2. bDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA
  3. cInstitutional Office of Regulated Nonclinical Studies, University of Texas Medical Branch, Galveston, Texas, USA
  4. dDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
  5. eSealy Institute for Vaccine Sciences, University of Texas Medical Branch, Galveston, Texas, USA
  6. fBioscience Division, SRI International, Menlo Park, California, USA
  • Address correspondence to Peter B. Madrid, peter.madrid{at}sri.com, or Sean Ekins, sean{at}collaborationspharma.com.
  • Citation Lane TR, Comer JE, Freiberg AN, Madrid PB, Ekins S. 2019. Repurposing quinacrine against Ebola virus infection in vivo. Antimicrob Agents Chemother 63:e01142-19. https://doi.org/10.1128/AAC.01142-19.

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Repurposing Quinacrine against Ebola Virus Infection In Vivo
Thomas R. Lane, Jason E. Comer, Alexander N. Freiberg, Peter B. Madrid, Sean Ekins
Antimicrobial Agents and Chemotherapy Aug 2019, 63 (9) e01142-19; DOI: 10.1128/AAC.01142-19

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Repurposing Quinacrine against Ebola Virus Infection In Vivo
Thomas R. Lane, Jason E. Comer, Alexander N. Freiberg, Peter B. Madrid, Sean Ekins
Antimicrobial Agents and Chemotherapy Aug 2019, 63 (9) e01142-19; DOI: 10.1128/AAC.01142-19
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KEYWORDS

Ebola virus
Ebola virus disease
antiviral
quinacrine

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