DOI: 10.1128/AAC.01663-19
ABSTRACT
Ceftriaxone (CRO) is widely used as the first-line treatment for gonococcal infections. However, CRO-resistant Neisseria gonorrhoeae strains carrying mosaic penA-60.001 have emerged recently and disseminated worldwide. To meet the urgent need to detect these strains, we report here a loop-mediated isothermal amplification (LAMP) assay system that targets N. gonorrhoeae penA-60.001. This assay system can differentiate N. gonorrhoeae strains carrying mosaic penA-60.001 from strains carrying other penA alleles.
FOOTNOTES
- Received 16 August 2019.
- Returned for modification 9 September 2019.
- Accepted 19 October 2019.
- Accepted manuscript posted online 28 October 2019.
Supplemental material is available online only.
- Copyright © 2019 American Society for Microbiology.
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