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Experimental Therapeutics

Nitroxide Functionalized Antibiotics Are Promising Eradication Agents against Staphylococcus aureus Biofilms

Anthony D. Verderosa, Rabeb Dhouib, Kathryn E. Fairfull-Smith, Makrina Totsika
Anthony D. Verderosa
aSchool of Chemistry, Physics, and Mechanical Engineering, Queensland University of Technology, Brisbane, Queensland, Australia
bInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
cSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
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Rabeb Dhouib
bInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
cSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
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Kathryn E. Fairfull-Smith
aSchool of Chemistry, Physics, and Mechanical Engineering, Queensland University of Technology, Brisbane, Queensland, Australia
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Makrina Totsika
bInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
cSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
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  • ORCID record for Makrina Totsika
DOI: 10.1128/AAC.01685-19
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Article Information

DOI 
https://doi.org/10.1128/AAC.01685-19
PubMed 
31636066

Published By 
American Society for Microbiology Journals
History 
  • Received August 19, 2019
  • Returned for modification September 3, 2019
  • Accepted October 9, 2019
  • Published online December 20, 2019.

Copyright & Usage 
Copyright © 2019 Verderosa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Article Versions

  • Accepted Manuscript version (October 21, 2019).
  • You are viewing the most recent version of this article.

Author Information

  1. Anthony D. Verderosaa,b,c,
  2. Rabeb Dhouibb,c,
  3. Kathryn E. Fairfull-Smitha and
  4. Makrina Totsikab,c
  1. aSchool of Chemistry, Physics, and Mechanical Engineering, Queensland University of Technology, Brisbane, Queensland, Australia
  2. bInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
  3. cSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
  • Address correspondence to Kathryn E. Fairfull-Smith, k.fairfull-smith{at}qut.edu.au, or Makrina Totsika, makrina.totsika{at}qut.edu.au.
  • Citation Verderosa AD, Dhouib R, Fairfull-Smith KE, Totsika M. 2020. Nitroxide functionalized antibiotics are promising eradication agents against Staphylococcus aureus biofilms. Antimicrob Agents Chemother 64:e01685-19. https://doi.org/10.1128/AAC.01685-19.

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Nitroxide Functionalized Antibiotics Are Promising Eradication Agents against Staphylococcus aureus Biofilms
Anthony D. Verderosa, Rabeb Dhouib, Kathryn E. Fairfull-Smith, Makrina Totsika
Antimicrobial Agents and Chemotherapy Dec 2019, 64 (1) e01685-19; DOI: 10.1128/AAC.01685-19

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Nitroxide Functionalized Antibiotics Are Promising Eradication Agents against Staphylococcus aureus Biofilms
Anthony D. Verderosa, Rabeb Dhouib, Kathryn E. Fairfull-Smith, Makrina Totsika
Antimicrobial Agents and Chemotherapy Dec 2019, 64 (1) e01685-19; DOI: 10.1128/AAC.01685-19
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KEYWORDS

Staphylococcus aureus
Calgary Biofilm Device
fluorescent probes
Gram-positive bacteria
antibiofilm
antibiotics
biofilm dispersal
biofilm eradication
fluoroquinolones
infection
nitroxide

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