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Experimental Therapeutics

In Vitro and In Vivo Efficacies of the EGFR/MEK/ERK Signaling Inhibitors in the Treatment of Alveolar Echinococcosis

Zhe Cheng, Zhijian Xu, Huimin Tian, Fan Liu, Xiu Li, Damin Luo, Yanhai Wang
Zhe Cheng
aState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
bParasitology Research Laboratory, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
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Zhijian Xu
aState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
bParasitology Research Laboratory, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
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Huimin Tian
cMedical College, Xiamen University, Xiamen, Fujian, China
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Fan Liu
cMedical College, Xiamen University, Xiamen, Fujian, China
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Xiu Li
aState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
bParasitology Research Laboratory, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
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Damin Luo
aState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
bParasitology Research Laboratory, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
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Yanhai Wang
aState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
bParasitology Research Laboratory, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
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  • ORCID record for Yanhai Wang
DOI: 10.1128/AAC.00341-20
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Article Information

DOI 
https://doi.org/10.1128/AAC.00341-20
PubMed 
32482675

Published By 
American Society for Microbiology Journals
History 
  • Received February 21, 2020
  • Returned for modification April 30, 2020
  • Accepted May 25, 2020
  • Published online July 22, 2020.

Copyright & Usage 
Copyright © 2020 Cheng et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Article Versions

  • Accepted Manuscript version (June 01, 2020).
  • You are viewing the most recent version of this article.

Author Information

  1. Zhe Chenga,b,
  2. Zhijian Xua,b,
  3. Huimin Tianc,
  4. Fan Liuc,
  5. Xiu Lia,b,
  6. Damin Luoa,b and
  7. Yanhai Wanga,b
  1. aState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
  2. bParasitology Research Laboratory, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
  3. cMedical College, Xiamen University, Xiamen, Fujian, China
  • Address correspondence to Yanhai Wang, wangyh{at}xmu.edu.cn.
  • Citation Cheng Z, Xu Z, Tian H, Liu F, Li X, Luo D, Wang Y. 2020. In vitro and in vivo efficacies of the EGFR/MEK/ERK signaling inhibitors in the treatment of alveolar echinococcosis. Antimicrob Agents Chemother 64:e00341-20. https://doi.org/10.1128/AAC.00341-20.

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In Vitro and In Vivo Efficacies of the EGFR/MEK/ERK Signaling Inhibitors in the Treatment of Alveolar Echinococcosis
Zhe Cheng, Zhijian Xu, Huimin Tian, Fan Liu, Xiu Li, Damin Luo, Yanhai Wang
Antimicrobial Agents and Chemotherapy Jul 2020, 64 (8) e00341-20; DOI: 10.1128/AAC.00341-20

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In Vitro and In Vivo Efficacies of the EGFR/MEK/ERK Signaling Inhibitors in the Treatment of Alveolar Echinococcosis
Zhe Cheng, Zhijian Xu, Huimin Tian, Fan Liu, Xiu Li, Damin Luo, Yanhai Wang
Antimicrobial Agents and Chemotherapy Jul 2020, 64 (8) e00341-20; DOI: 10.1128/AAC.00341-20
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    • ABSTRACT
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KEYWORDS

EGFR signaling
apoptosis
Echinococcosis
germinative cells

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