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Epidemiology and Surveillance

In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile

Khurshida Begum, Eugénie Bassères, Julie Miranda, Chris Lancaster, Anne J. Gonzales-Luna, Travis J. Carlson, Tasnuva Rashid, David W. Eyre, Mark H. Wilcox, M. Jahangir Alam, Kevin W. Garey
Khurshida Begum
aUniversity of Houston College of Pharmacy, Houston, Texas, USA
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Eugénie Bassères
aUniversity of Houston College of Pharmacy, Houston, Texas, USA
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Julie Miranda
aUniversity of Houston College of Pharmacy, Houston, Texas, USA
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Chris Lancaster
aUniversity of Houston College of Pharmacy, Houston, Texas, USA
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Anne J. Gonzales-Luna
aUniversity of Houston College of Pharmacy, Houston, Texas, USA
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Travis J. Carlson
bFred Wilson School of Pharmacy, High Point University, High Point, North Carolina, USA
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Tasnuva Rashid
aUniversity of Houston College of Pharmacy, Houston, Texas, USA
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David W. Eyre
cBig Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
dNational Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom
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Mark H. Wilcox
eHealthcare Associated Infections Research Group, Leeds Institute for Medical Research, University of Leeds, Old Medical School, Leeds General Infirmary, Leeds, United Kingdom
fMicrobiology, Leeds Teaching Hospitals NHS Trust, Old Medical School, Leeds General Infirmary, Leeds, United Kingdom
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M. Jahangir Alam
aUniversity of Houston College of Pharmacy, Houston, Texas, USA
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Kevin W. Garey
aUniversity of Houston College of Pharmacy, Houston, Texas, USA
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  • ORCID record for Kevin W. Garey
DOI: 10.1128/AAC.00522-20
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Article Information

DOI 
https://doi.org/10.1128/AAC.00522-20
PubMed 
32513796

Published By 
American Society for Microbiology Journals
History 
  • Received March 23, 2020
  • Returned for modification May 24, 2020
  • Accepted May 31, 2020
  • Published online July 22, 2020.

Copyright & Usage 
Copyright © 2020 Begum et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Article Versions

  • Accepted Manuscript version (June 08, 2020).
  • You are viewing the most recent version of this article.

Author Information

  1. Khurshida Beguma,
  2. Eugénie Bassèresa,
  3. Julie Mirandaa,
  4. Chris Lancastera,
  5. Anne J. Gonzales-Lunaa,
  6. Travis J. Carlsonb,
  7. Tasnuva Rashida,
  8. David W. Eyrec,d,
  9. Mark H. Wilcoxe,f,
  10. M. Jahangir Alama and
  11. Kevin W. Gareya
  1. aUniversity of Houston College of Pharmacy, Houston, Texas, USA
  2. bFred Wilson School of Pharmacy, High Point University, High Point, North Carolina, USA
  3. cBig Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
  4. dNational Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom
  5. eHealthcare Associated Infections Research Group, Leeds Institute for Medical Research, University of Leeds, Old Medical School, Leeds General Infirmary, Leeds, United Kingdom
  6. fMicrobiology, Leeds Teaching Hospitals NHS Trust, Old Medical School, Leeds General Infirmary, Leeds, United Kingdom
  • Address correspondence to Kevin W. Garey, kgarey{at}uh.edu.
  • Citation Begum K, Bassères E, Miranda J, Lancaster C, Gonzales-Luna AJ, Carlson TJ, Rashid T, Eyre DW, Wilcox MH, Alam MJ, Garey KW. 2020. In vitro activity of omadacycline, a new tetracycline analog, and comparators against Clostridioides difficile. Antimicrob Agents Chemother 64:e00522-20. https://doi.org/10.1128/AAC.00522-20.

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In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile
Khurshida Begum, Eugénie Bassères, Julie Miranda, Chris Lancaster, Anne J. Gonzales-Luna, Travis J. Carlson, Tasnuva Rashid, David W. Eyre, Mark H. Wilcox, M. Jahangir Alam, Kevin W. Garey
Antimicrobial Agents and Chemotherapy Jul 2020, 64 (8) e00522-20; DOI: 10.1128/AAC.00522-20

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In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile
Khurshida Begum, Eugénie Bassères, Julie Miranda, Chris Lancaster, Anne J. Gonzales-Luna, Travis J. Carlson, Tasnuva Rashid, David W. Eyre, Mark H. Wilcox, M. Jahangir Alam, Kevin W. Garey
Antimicrobial Agents and Chemotherapy Jul 2020, 64 (8) e00522-20; DOI: 10.1128/AAC.00522-20
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KEYWORDS

anaerobe
pharmacology
susceptibility
time-kill studies

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