DOI: 10.1128/AAC.00865-20
ABSTRACT
Here, we characterize the fosA genes from three Escherichia coli clinical isolates recovered from Canadian patients. Each fosA sequence was individually overexpressed in E. coli BW25113, and antimicrobial susceptibility testing was performed to assess their role in fosfomycin resistance. The findings from this study identify and functionally characterize FosA3, FosA8, and novel FosA7 members and highlight the importance of phenotypic characterization of fosA genes.
FOOTNOTES
- Received 1 May 2020.
- Returned for modification 22 May 2020.
- Accepted 16 October 2020.
- Accepted manuscript posted online 19 October 2020.
Supplemental material is available online only.
- Copyright © 2020 American Society for Microbiology.
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