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OXA-48 Carbapenemase Producing Salmonella enterica Kentucky of ST198 in a Patient Transferred from Libya to Switzerland

Salome N. Seiffert, Vincent Perreten, Sönke Johannes, Sara Droz, Thomas Bodmer, Andrea Endimiani
Salome N. Seiffert
1Institute for Infectious Diseases, University of Bern, Bern, Switzerland
2Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
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Vincent Perreten
2Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
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Sönke Johannes
4Rehaklinik Bellikon, Bellikon, Switzerland
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Sara Droz
1Institute for Infectious Diseases, University of Bern, Bern, Switzerland
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Thomas Bodmer
5 labormedizinisches zentrum Dr Risch, Department of Medical Microbiology, Bern-Liebefeld, Switzerland
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Andrea Endimiani
1Institute for Infectious Diseases, University of Bern, Bern, Switzerland
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  • For correspondence: aendimiani@gmail.com andrea.endimiani@ifik.unibe.ch
DOI: 10.1128/AAC.02417-13
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ABSTRACT

We report a case of OXA-48-producing Salmonella enterica Kentucky of ST198 from perianal screening cultures of a patient transferred from Libya to Switzerland. The blaOXA-48 was carried by Tn1999.2 and located on a ∼60Kb IncL/M plasmid. Salmonella also possessed blaVEB-8, aac (6)-Ib, tet(A), sul1 and mphA resistance genes and substitutions in GyrA (Ser83Phe and Asp87Asn) and ParC (Ser80I1e). This finding emphasizes that prompt screening strategies are essential to prevent the dissemination of carbapenemase producers imported from endemic countries.

FOOTNOTES

  • ↵*Corresponding author: Andrea Endimiani, MD, PhD - Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, Postfach 61, CH-3010, Switzerland - Phone: +41-31-632-8632; Fax +41-31-632-8766. E-mails:aendimiani{at}gmail.com;andrea.endimiani{at}ifik.unibe.ch
  • Copyright © 2014, American Society for Microbiology. All Rights Reserved.
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OXA-48 Carbapenemase Producing Salmonella enterica Kentucky of ST198 in a Patient Transferred from Libya to Switzerland
Salome N. Seiffert, Vincent Perreten, Sönke Johannes, Sara Droz, Thomas Bodmer, Andrea Endimiani
Antimicrobial Agents and Chemotherapy Jan 2014, AAC.02417-13; DOI: 10.1128/AAC.02417-13

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OXA-48 Carbapenemase Producing Salmonella enterica Kentucky of ST198 in a Patient Transferred from Libya to Switzerland
Salome N. Seiffert, Vincent Perreten, Sönke Johannes, Sara Droz, Thomas Bodmer, Andrea Endimiani
Antimicrobial Agents and Chemotherapy Jan 2014, AAC.02417-13; DOI: 10.1128/AAC.02417-13
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