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Accepted Manuscripts

January 19, 2021

  • Clinical Therapeutics
    Variability of Hydroxy-Itraconazole in Relation to Itraconazole Bloodstream Concentrations
    Nathan P. Wiederhold, Ilan S. Schwartz, Thomas F. Patterson, George R. Thompson
  • Experimental Therapeutics
    The benzimidazole SPR719 shows promising concentration-dependent activity and synergy against nontuberculous mycobacteria
    Lian J. Pennings, Mike Marvin Ruth, Heiman F.L. Wertheim, Jakko van Ingen
  • Letter to the Editor
    Characterization of an IncFIB/IncHI1B plasmid encoding efflux pump TMexCD1-TOprJ1 in a clinical tigecycline and carbapenem-resistant Klebsiella pneumoniae strain
    Xuemei Yang, Lianwei Ye, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen
  • Open Access
    Experimental Therapeutics
    In vivo targeting of E. coli with vancomycin-arginine
    Lewis F. Neville, Itamar Shalit, Peter A. Warn, Marc H. Scheetz, Jiuzhi Sun, Madeline B. Chosy, Paul A. Wender, Lynette Cegelski, Jacob T. Rendell
  • Open Access
    Susceptibility
    Synergistic rifabutin and colistin reduce emergence of resistance when treating Acinetobacter baumannii
    Jiaqi Cheng, Jun Yan, Zeferino Reyna, Matt Slarve, Peggy Lu, Brad Spellberg, Brian Luna
  • Mechanisms of Resistance
    Tetracycline resistance mediated by tet(M) has variable Integrative Conjugative Element composition in Mycoplasma hominis isolated in the United Kingdom from 2005-2015.
    Victoria J Chalker, Martin G. Sharratt, Christopher Rees, Oliver H. Bell, Edward Portal, Kirsty Sands, Matthew S. Payne, Owen B. Spiller
  • Susceptibility
    Assessment of piperacillin-tazobactam-meropenem synergy against serine carbapenemase producing Enterobacterales using time kill assays
    Alexander Lawandi, Gleice C. Leite, Matthew P. Cheng, Brigitte Lefebvre, Jean Longtin, Todd C. Lee
  • Letter to the Editor
    Identification of Tn6835 and a Novel Genomic Island MMGI-1 in a Pan-Resistant Morganella morganii Strain
    Rong Xiang, Meng Li
  • Experimental Therapeutics
    Deletion of PknG abates reactivation of latent Mycobacterium tuberculosis in mice
    Mehak Zahoor Khan, Vinay Kumar Nandicoori
  • Susceptibility
    In vitro resistance and evolution of resistance to tavaborole in Trichophyton rubrum
    Diletta Mazzantini, Francesco Celandroni, Marco Calvigioni, Antonella Lupetti, Emilia Ghelardi
  • Experimental Therapeutics
    Dose-fractionation of moxifloxacin for the treatment of tuberculosis: impact of dosing interval and elimination half-life on microbial kill and resistance suppression
    G.L. Drusano, Stephanie Rogers, David Brown, CA Peloquin, Michael Neely, Walter Yamada, Sarah Kim, Mohammed Almoslem, Stephan Schmidt, Arnold Louie
  • Mechanisms of Resistance
    Daptomycin resistance in Enterococcus faecium can be delayed by disruption of the LiaFSR stress response pathway
    Amy G. Prater, Heer H. Mehta, Kathryn Beabout, Adeline Supandy, William R. Miller, Truc T. Tran, Cesar A. Arias, Yousif Shamoo
  • Open Access
    Experimental Therapeutics
    The antibiotic negamycin crosses the bacterial cytoplasmic membrane by multiple routes
    Daniel Hörömpöli, Catherine Ciglia, Karl-Heinz Glüsenkamp, Lars Ole Haustedt, Hildegard Falkenstein-Paul, Gerd Bendas, Anne Berscheid, Heike Brötz-Oesterhelt
  • Open Access
    Pharmacology
    Semi-mechanistic pharmacokinetic and pharmacodynamic modelling of piperaquine in a volunteer infection study with Plasmodium falciparum blood-stage malaria
    Thanaporn Wattanakul, Mark Baker, Joerg Mohrle, Brett McWhinney, Richard M. Hoglund, James S. McCarthy, Joel Tarning
  • Experimental Therapeutics
    Boromycin has potent anti-Toxoplasma and anti-Cryptosporidium activity
    Jaypee Abenoja, Alexis Cotto-Rosario, Roberta O’Connor
  • Open Access
    Antiviral Agents
    Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs
    Shawn Herring, Jessica M. Oda, Jessica Wagoner, Delaney Kirchmeier, Aidan O’Connor, Elizabeth A. Nelson, Qinfeng Huang, Yuying Liang, Lisa Evans DeWald, Lisa M. Johansen, Pamela J. Glass, Gene G. Olinger, Aleksandr Ianevski, Tero Aittokallio, Mary F. Paine, Susan L. Fink, Judith M. White, Stephen J. Polyak
  • Pharmacology
    Therapeutic potential of Fosmanogepix (APX001) for intra-abdominal candidiasis: from lesion penetration to efficacy in a mouse model
    Annie Lee, Ning Wang, Claire L. Carter, Matthew Zimmerman, Véronique Dartois, Karen Joy Shaw, David S. Perlin, Yanan Zhao
  • Mechanisms of Resistance
    Carbapenem use is driving the evolution of IMiPenemase (IMP)-1 variants
    Zishuo Cheng, Christopher R. Bethel, Pei W. Thomas, Ben A. Shurina, John-Paul Alao, Caitlyn A. Thomas, Kundi Yang, Huan Zhang, Aidan M. Sturgill, Andrea N. Kravats, Richard C. Page, Walter Fast, Robert A. Bonomo, Michael W. Crowder
  • Experimental Therapeutics
    Development and Characterization of Monoolein-Based Liposomes of Carvacrol, Cinnamaldehyde, Citral or Thymol with anti-Candida Activities
    Katherine Miranda-Cadena, Marisol Dias, Augusto Costa-Barbosa, Tony Collins, Cristina Marcos-Arias, Elena Eraso, Célia Pais, Guillermo Quindós, Paula Sampaio
  • Mechanisms of Resistance
    Modulation of Human Beta-Defensin 2 Expression by Pathogenic Neisseria meningitidis and Commensal Lactobacilli
    Gabriela M. Wassing, Nathalie Ilehag, Jonas Frey, Ann-Beth Jonsson

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DISCLAIMER: These manuscripts are provided "as is" without warranty of any kind, either expressly for a particular purpose, or non-infringement. Changes will be made to these manuscripts before publication. Review and/or use or reliance on these materials is at the discretion and risk of the reader/user. In no event shall the American Society for Microbiology be liable for damages of any kind arising from these materials; references to products or publications do not imply endorsement of those products or publications.

Accepted Manuscripts are PDF versions of manuscripts that have been peer reviewed and accepted but not yet copyedited. The manuscripts are published online as soon as possible after acceptance, on a weekly basis, before the copyedited, typeset articles are published. They are posted "as is" (i.e., as submitted by the authors at the modification stage) and do not reflect ASM editorial changes. No corrections/changes to the PDF manuscripts are accepted. Accordingly, there likely will be differences between the accepted manuscripts and the final, typeset articles. The manuscripts remain listed on the Accepted Manuscripts page until the final, typeset articles are posted. Supplemental material intended, and accepted, for publication is not posted until publication of the final, typeset articles.

Antimicrobial Agents and Chemotherapy: 65 (2)

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volume 65, issue 2
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  • Mechanism-of-Action Classification of Antibiotics by Global Transcriptome Profiling
  • Fact versus Fiction: a Review of the Evidence behind Alcohol and Antibiotic Interactions
  • New Perspectives on Antimicrobial Agents: Remdesivir Treatment for COVID-19
  • Updated Approaches against SARS-CoV-2
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