PT  - JOURNAL ARTICLE
AU  - Doern, Gary V.
AU  - Jones, Ronald N.
AU  - Pfaller, Michael A.
AU  - Kugler, Kari
AU  - , 
TI  - <em>Haemophilus influenzae</em> and <em>Moraxella catarrhalis</em> from Patients with Community-Acquired Respiratory Tract Infections: Antimicrobial Susceptibility Patterns from the SENTRY Antimicrobial  Surveillance Program (United States  and Canada, 1997)
AID  - 10.1128/AAC.43.2.385
DP  - 1999 Feb 01
TA  - Antimicrobial Agents and Chemotherapy
PG  - 385--389
VI  - 43
IP  - 2
4099  - http://aac.asm.org/content/43/2/385.short
4100  - http://aac.asm.org/content/43/2/385.full
SO  - Antimicrob. Agents Chemother.1999 Feb 01; 43
AB  - Between February and June of 1997, a large number of community-acquired respiratory tract isolates of Haemophilus influenzae (n = 1,077) and Moraxella catarrhalis (n = 503) from 27 U.S. and 7 Canadian medical centers were characterized as part of the SENTRY Antimicrobial Surveillance Program. Overall prevalences of β-lactamase production were 33.5% in H. influenzae and 92.2% in M. catarrhalis with no differences noted between isolates recovered in the United States and those from Canada. Among a total of 21 different antimicrobial agents tested, including six cephalosporins, a β-lactamase inhibitor combination, three macrolides, tetracycline, trimethoprim-sulfamethoxazole (TMP-SMX), rifampin, chloramphenicol, five fluoroquinolones, and quinupristin-dalfopristin, resistance rates of >5% with H. influenzae were observed only with cefaclor (12.8%) and TMP-SMX (16.2%).