PT  - JOURNAL ARTICLE
AU  - Tanaka, Kaori
AU  - Mikamo, Hiroshige
AU  - Nakao, Ken'ichi
AU  - Watanabe, Kunitomo
TI  - In Vitro Antianaerobic Activity of DX-619, a New Des-Fluoro(6) Quinolone
AID  - 10.1128/AAC.00639-06
DP  - 2006 Nov 01
TA  - Antimicrobial Agents and Chemotherapy
PG  - 3908--3913
VI  - 50
IP  - 11
4099  - http://aac.asm.org/content/50/11/3908.short
4100  - http://aac.asm.org/content/50/11/3908.full
SO  - Antimicrob. Agents Chemother.2006 Nov 01; 50
AB  - The in vitro activity of DX-619, a new des-F(6) quinolone, against anaerobic bacteria was evaluated. DX-619 showed potent activity against Bacteroides, Prevotella, Fusobacterium, Micromonas, Actinomyces, and Clostridium spp., with MIC50s/MIC90s of ≤0.03 to 0.25/≤0.03 to 1 μg/ml, respectively. DX-619 was also active against imipenem-resistant Bacteroides spp., with MIC50s/MIC90s of 0.25/1 μg/ml, respectively.